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Questions and Answers
What stimulates the rapid movement of preformed adhesion modules to the surface of endothelial cells?
Inflammation, infection, or trauma.
What happens when endothelial P selectin recognizes its counter receptors on neutrophils?
The neutrophils slow down, roll, or stop.
What is the process called when white blood cells gather along the endothelium?
Pavementing.
If the inflammatory stimulus is weak, what happens to the neutrophils after a few seconds or minutes?
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What other adhesion molecules come into play if the inflammatory stimulus is stronger?
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What is the process called when white blood cells move to the endothelium (vessel wall) during inflammation?
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What molecules on the endothelium attach to the adhesion molecules on the white blood cells during inflammation?
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What is the term used to describe when a layer of white blood cells stick to the endothelium during inflammation?
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How does the slowing of blood flow contribute to the increased contact between red blood cells and the endothelium during inflammation?
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What is the term used to describe the phenomenon where white blood cells roll slowly along the walls of the capillaries and venules, and may momentarily stop, during inflammation?
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What is the main reason for the margination of white blood cells during inflammation, aside from the slowing of blood flow?
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