10 Questions
What is the purpose of the MarginProbe® Radiofrequency Spectroscopy System?
Identifies positive margins by detecting microscopic residual cancer and DCIS.
Which methods of current margin assessment are mentioned in the content?
All of the above
What are the drawbacks of Full Cavity Shave as mentioned in the content?
Can compromise cosmetic outcomes due to volume of healthy tissue removed. Thinner shaves can result in reduced success clearing final margins.
What are some impacts of re-excision surgery as mentioned in the content?
Increased financial burden, complications, delays in adjuvant treatment, and compromises in IORT.
True or False: As tissue becomes malignant, its cellular morphology and electrical behavior remain the same.
False
What is the Margin Probe® Radiofrequency Spectroscopy System used for?
Identifying positive margins in breast cancer surgery
Why can't Gross Assessment and Specimen X-Ray fully address the need for margin assessment?
They cannot visualize microscopic invasive cancer nor DCIS
MarginProbe® reduces the need for re-excision surgery by identifying ______ margins.
positive
Frozen Section technique can add significant time to the breast cancer surgery procedure.
True
Match the following breast cancer margin assessment methods with their limitations:
Gross Assessment, Specimen X-Ray = Low sensitivity for ILC Frozen Section = Difficult due to fatty nature of breast tissue Full Cavity Shave = Can compromise cosmetic outcomes due to volume of healthy tissue removed
Study Notes
Margin Probe
- A radiofrequency spectroscopy system that identifies positive margins in real-time by detecting microscopic residual cancer and DCIS at the surface of excised breast tissue.
- Enables immediate action by the surgeon, reducing the need for re-excision surgery.
Limitations of Current Margin Assessment Methods
- Gross assessment and specimen X-ray cannot palpate/visualize microscopic invasive cancer nor DCIS and have low sensitivity for ILC.
- Frozen section assessment is difficult due to the fatty nature of breast tissue and may add significant time to the procedure.
- Full cavity shave can compromise cosmetic outcomes due to the volume of healthy tissue removed, and thinner shaves to manage tissue volume can result in reduced success in clearing final margins.
Impact of Re-Excision
- Increased financial burden to the healthcare system, with an average cost of $16,000 per procedure.
- Impacts patient satisfaction, leading to decreased satisfaction and potential delays in adjuvant treatment.
- Compromises IORT and oncoplastic procedures.
- Not aligned with the shift from volume to value-based care.
How MarginProbe Works
- Tissue becomes malignant, its cellular morphology and electrical behavior change.
- The system uses radiofrequency spectroscopy to detect these changes, enabling real-time identification of positive margins.
Margin Probe
- A radiofrequency spectroscopy system that identifies positive margins in real-time by detecting microscopic residual cancer and DCIS at the surface of excised breast tissue.
- Enables immediate action by the surgeon, reducing the need for re-excision surgery.
Limitations of Current Margin Assessment Methods
- Gross assessment and specimen X-ray cannot palpate/visualize microscopic invasive cancer nor DCIS and have low sensitivity for ILC.
- Frozen section assessment is difficult due to the fatty nature of breast tissue and may add significant time to the procedure.
- Full cavity shave can compromise cosmetic outcomes due to the volume of healthy tissue removed, and thinner shaves to manage tissue volume can result in reduced success in clearing final margins.
Impact of Re-Excision
- Increased financial burden to the healthcare system, with an average cost of $16,000 per procedure.
- Impacts patient satisfaction, leading to decreased satisfaction and potential delays in adjuvant treatment.
- Compromises IORT and oncoplastic procedures.
- Not aligned with the shift from volume to value-based care.
How MarginProbe Works
- Tissue becomes malignant, its cellular morphology and electrical behavior change.
- The system uses radiofrequency spectroscopy to detect these changes, enabling real-time identification of positive margins.
This quiz is about the Margin Probe, a radiofrequency spectroscopy system that helps reduce re-excision in breast cancer surgery by detecting microscopic residual cancer.
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