Podcast
Questions and Answers
What does the retrospective evaluation of children with Marfan syndrome suggest about beta-blocker treatment?
What does the retrospective evaluation of children with Marfan syndrome suggest about beta-blocker treatment?
- It accelerated aortic growth rate
- It had no impact on aortic growth rate
- It prevented aneurysm formation
- It was associated with a reduced aortic growth rate (correct)
What did randomized trials comparing an ARB to a beta blocker in patients with Marfan syndrome find?
What did randomized trials comparing an ARB to a beta blocker in patients with Marfan syndrome find?
- Significant reduction in aortic root growth rate with ARB compared to beta blocker
- Significant reduction in clinical events with ARB compared to beta blocker
- No significant difference in aortic root growth rate or clinical events between the 2 treatment groups (correct)
- Higher clinical events with ARB compared to beta blocker
What did multiple trials comparing the addition of an ARB to beta-blocker therapy in patients with Marfan syndrome show?
What did multiple trials comparing the addition of an ARB to beta-blocker therapy in patients with Marfan syndrome show?
- Prevention of aneurysm formation
- Acceleration of aortic root growth rates over a 3- to 5-year follow-up
- Reduction of aortic root growth rates over a 3- to 5-year follow-up (correct)
- No impact on aortic root growth rates over a 3- to 5-year follow-up
What was the outcome of losartan treatment in a small, nonrandomized open-label study of children with Marfan syndrome who had previously had rapid aortic root growth?
What was the outcome of losartan treatment in a small, nonrandomized open-label study of children with Marfan syndrome who had previously had rapid aortic root growth?
What did a meta-analysis confirm about combination therapy of ARB and beta-blocker in patients with Marfan syndrome?
What did a meta-analysis confirm about combination therapy of ARB and beta-blocker in patients with Marfan syndrome?
What is the approximate reoperation rate over 20 years for adult patients with certain cardiac conditions?
What is the approximate reoperation rate over 20 years for adult patients with certain cardiac conditions?
What should symptoms like dyspnea, fatigue, edema, or ascites in adult patients indicate?
What should symptoms like dyspnea, fatigue, edema, or ascites in adult patients indicate?
What is the likely consequence of recurrent stenosis in adult patients?
What is the likely consequence of recurrent stenosis in adult patients?
What is the potential implication of ventricular dysfunction precluding further surgery in adult patients?
What is the potential implication of ventricular dysfunction precluding further surgery in adult patients?
What may preclude heart transplantation in adult patients?
What may preclude heart transplantation in adult patients?
