Management of Reproductive Disorders test
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Questions and Answers

What is the rationale for treating post-menopausal women with hormone replacement therapy (HRT)?

  • To worsen menopausal symptoms
  • To increase the risk of endometrial cancer
  • To induce hypertension
  • To prevent osteoporotic fractures (correct)
  • Why is it recommended to treat women with a uterus with combined oestrogen/progestogen therapy?

  • To prevent weight gain
  • To treat hypertension
  • To decrease the risk of thrombosis
  • To reduce the risk of endometrial cancer (correct)
  • What is a potential concern when administering higher-dose HRT?

  • Weight loss
  • Fluid retention (correct)
  • Reduced risk of osteoporosis
  • Decreased risk of thrombosis
  • In post-menopausal women, what are the associated risks of undergoing long-term HRT?

    <p>Adverse effects related to the duration of therapy and age</p> Signup and view all the answers

    When is it generally recommended to discontinue oestrogen replacement therapy?

    <p>After 5 years of therapy</p> Signup and view all the answers

    Why might lower-dose oral or transdermal HRT be more appropriate for some patients?

    <p>To reduce oestrogenic side-effects</p> Signup and view all the answers

    What is the most reliable 'test' of ovarian function in pre-menopausal women?

    <p>Careful menstrual history</p> Signup and view all the answers

    What can confirm ovulation in women during the menstrual cycle?

    <p>Plasma progesterone measurement during luteal phase</p> Signup and view all the answers

    At what age does the cessation of menstruation (menopause) typically occur in high-income countries?

    <p>50 years</p> Signup and view all the answers

    What happens in the 5 years before menopause that is referred to as the climacteric?

    <p>Gradual increase in anovulatory cycles</p> Signup and view all the answers

    What hormonal changes occur leading to menopause?

    <p>Increased pituitary secretion of LH and FSH</p> Signup and view all the answers

    What is the recommended age limit for continuing hormone replacement therapy (HRT) in patients with premature menopause?

    <p>Around 50 years</p> Signup and view all the answers

    When should HRT be continued beyond the age of around 50 years in patients with premature menopause?

    <p>If there are persistent symptoms of estrogen deficiency</p> Signup and view all the answers

    What are some clinical features of male hypogonadism?

    <p>Gynecomastia and infertility</p> Signup and view all the answers

    What is one of the postulated mechanisms contributing to mild hypogonadism in older men?

    <p>Reduction in testosterone levels with age</p> Signup and view all the answers

    Which hormone is commonly measured in older men as part of an assessment for erectile dysfunction and lack of libido?

    <p>Testosterone</p> Signup and view all the answers

    How is male hypogonadism confirmed?

    <p>Low fasting serum testosterone level at 0900-hr</p> Signup and view all the answers

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