Mammogram and Breast Cancer Detection

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Questions and Answers

What is the primary mechanism of action of LHRH agonists?

They stimulate the pituitary gland to produce more LH, leading to an initial increase in estrogen production (correct)
They have no direct effect on the endocrine system, and only act on peripheral tissues
They directly bind to and inhibit the ovaries, reducing estrogen production
They directly inhibit the pituitary gland to reduce LH production

What is the purpose of using LHRH agonists in the treatment of certain conditions?

To stimulate the pituitary gland to produce more FSH, which then increases testosterone levels
To cause an initial increase in estrogen production, followed by a sustained reduction in estrogen levels (correct)
To directly inhibit estrogen production and lower estrogen levels
LHRH agonists have no clinical applications and are not used to treat any conditions

What is the term used to describe the initial increase in estrogen production that occurs with LHRH agonist treatment?

Estrogen flare (correct)
Estrogen elevation
Estrogen spike
Estrogen surge

How do LHRH agonists differ in their mechanism of action compared to LHRH antagonists?

LHRH agonists initially stimulate the pituitary to increase LH and estrogen, while LHRH antagonists directly block the pituitary-gonadal axis (A) Signup and view all the answers

Which of the following is a potential clinical application of using LHRH agonists?

Treatment of prostate cancer by reducing testosterone levels (B) Signup and view all the answers

What is the rationale for the initial increase in estrogen production observed with LHRH agonist treatment?

The initial increase in estrogen production is necessary to stimulate the pituitary gland and induce a sustained reduction in estrogen levels (B) Signup and view all the answers

How do LHRH agonists ultimately lead to a reduction in estrogen production?

LHRH agonists cause desensitization of the pituitary gland to LHRH, leading to decreased LH and estrogen production (A) Signup and view all the answers