Malignant Fibrous Histiocytoma Overview

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Questions and Answers

Malignant fibrous histiocytoma is also known as Undifferentiated Pleomorphic Sarcoma.

True (A)

Soft-tissue MFH is most common in individuals aged 30 to 40 years.

False (B)

On x-ray, a soft-tissue MFH appears as a homogeneous, well-defined mass.

False (B)

Cortical erosion of the underlying bone is considered a significant diagnostic feature of MFH.

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MRI of soft-tissue MFH shows low signal intensity on T1 weighted sequences.

<p>False (B)</p> Signup and view all the answers

Flashcards

Malignant fibrous histiocytoma (MFH)

A type of soft tissue cancer that is often painless and grows slowly but can get very large.

Undifferentiated Pleomorphic Sarcoma (UPS)

A newer name for MFH. It's important to recognize that both terms refer to the same type of cancer.

Soft-tissue MFH

The most common type of MFH, often affecting people over 50.

Cortical erosion of the underlying bone

A significant sign of MFH, as the tumor eats away at the bone.

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High signal on both T1 and T2 weighted sequences (MRI)

A characteristic way MFH appears on an MRI scan, indicating a high water content.

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Study Notes

Malignant Fibrous Histiocytoma (MFH)

  • Also known as Undifferentiated Pleomorphic Sarcoma (UPS)
  • The most common subtype of MFH is a soft-tissue MFH
  • Most common malignant primary soft tissue tumour in those aged over 50
  • Typically presents as a painless enlarging soft tissue mass over months
  • Can be large at diagnosis, measuring tens of centimetres
  • X-ray appearance: partly calcified soft tissue mass
  • Important diagnostic feature: cortical erosion of underlying bone
  • MRI appearance: high signal on both T1 and T2 weighted sequences

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