Malaria: Overview and Fundamentals

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Questions and Answers

What is the origin of the term 'malaria'?

  • Greek
  • Medieval Italian (correct)
  • French
  • Latin

What is the type of malaria that is most likely to result in severe infections?

  • P.vivax
  • P. falciparum (correct)
  • P.malariae
  • P.ovale

What is the estimated number of malaria cases worldwide in 2020?

  • 200 million
  • 100 million
  • 241 million (correct)
  • 300 million

What is the incidence of malaria per 1000 population at risk in Pakistan in 2020?

<p>8.4 (B)</p> Signup and view all the answers

What is the primary mode of transmission of malaria?

<p>Mosquito bites (A)</p> Signup and view all the answers

What is the estimated number of malaria deaths worldwide in 2020?

<p>627 000 (C)</p> Signup and view all the answers

What is the type of malaria that is transmitted from animal to human?

<p>P.knowlesi (C)</p> Signup and view all the answers

What is the purpose of the expression of certain surface sticky proteins on infected RBCs?

<p>To facilitate the attachment of infected RBCs to the walls of vessels (B)</p> Signup and view all the answers

What is the result of the activation of endothelial cells by cytokines?

<p>The attachment of infected RBCs to the walls of vessels (C)</p> Signup and view all the answers

What is the outcome of the mechanisms employed by infected RBCs to avoid the immune response?

<p>Vascular clotting problems and occlusion (A)</p> Signup and view all the answers

What is the result of the occlusion of blood vessels in malaria?

<p>Ischemia of multiple vital organs (D)</p> Signup and view all the answers

What is the role of macrophages in the pathophysiology of malaria?

<p>To secrete cytokines, especially INF-a and INF-y (D)</p> Signup and view all the answers

What is the specificity of the Rapid Diagnostic Test (RDT) for diagnosing malaria?

<p>96.7% (B)</p> Signup and view all the answers

What is the primary goal of administering primaquine in the treatment of malaria?

<p>To prevent relapses (C)</p> Signup and view all the answers

Which of the following diagnostic tests is quantitative?

<p>Thick blood smear (D)</p> Signup and view all the answers

What is the primary indication for performing a lumbar puncture in a malaria patient?

<p>To diagnose cerebral malaria (C)</p> Signup and view all the answers

Which of the following laboratory tests is not typically used to monitor treatment response in malaria?

<p>G6PD levels (B)</p> Signup and view all the answers

What is the primary reason for administering blood transfusion in a malaria patient?

<p>To correct anemia (D)</p> Signup and view all the answers

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