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Malaria: Overview and Fundamentals

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Questions and Answers

What is the origin of the term 'malaria'?

Greek

Medieval Italian (correct)

French

Latin

What is the type of malaria that is most likely to result in severe infections?

P.vivax

P. falciparum (correct)

P.malariae

P.ovale

What is the estimated number of malaria cases worldwide in 2020?

200 million

100 million

241 million (correct)

300 million

What is the incidence of malaria per 1000 population at risk in Pakistan in 2020?

8.4 Signup and view all the answers

What is the primary mode of transmission of malaria?

Mosquito bites Signup and view all the answers

What is the estimated number of malaria deaths worldwide in 2020?

627 000 Signup and view all the answers

What is the type of malaria that is transmitted from animal to human?

P.knowlesi Signup and view all the answers

What is the purpose of the expression of certain surface sticky proteins on infected RBCs?

To facilitate the attachment of infected RBCs to the walls of vessels Signup and view all the answers

What is the result of the activation of endothelial cells by cytokines?

The attachment of infected RBCs to the walls of vessels Signup and view all the answers

What is the outcome of the mechanisms employed by infected RBCs to avoid the immune response?

Vascular clotting problems and occlusion Signup and view all the answers

What is the result of the occlusion of blood vessels in malaria?

Ischemia of multiple vital organs Signup and view all the answers

What is the role of macrophages in the pathophysiology of malaria?

To secrete cytokines, especially INF-a and INF-y Signup and view all the answers

What is the specificity of the Rapid Diagnostic Test (RDT) for diagnosing malaria?

96.7% Signup and view all the answers

What is the primary goal of administering primaquine in the treatment of malaria?

To prevent relapses Signup and view all the answers

Which of the following diagnostic tests is quantitative?

Thick blood smear Signup and view all the answers

What is the primary indication for performing a lumbar puncture in a malaria patient?

To diagnose cerebral malaria Signup and view all the answers

Which of the following laboratory tests is not typically used to monitor treatment response in malaria?

G6PD levels Signup and view all the answers

What is the primary reason for administering blood transfusion in a malaria patient?

To correct anemia Signup and view all the answers