Podcast
Questions and Answers
Which of the following clinical features is NOT associated with hypomagnesemia?
Which of the following clinical features is NOT associated with hypomagnesemia?
- Tetany
- Lethargy
- Seizures
- Bradycardia (correct)
What is the main treatment approach for hypomagnesemia?
What is the main treatment approach for hypomagnesemia?
- IV administration of calcium gluconate
- Oral magnesium replacement (correct)
- IV administration of potassium chloride
- IV administration of sodium bicarbonate
Which medication can contribute to the development of hypomagnesemia?
Which medication can contribute to the development of hypomagnesemia?
- Aspirin
- Calcium supplements
- Furosemide (correct)
- Antihistamines
Why do people with kidney disease have a higher risk of magnesium toxicity?
Why do people with kidney disease have a higher risk of magnesium toxicity?
What is a sign of magnesium toxicity according to the text?
What is a sign of magnesium toxicity according to the text?
In the body, what is the distribution of magnesium like?
In the body, what is the distribution of magnesium like?
What effect does Aldosterone have on plasma magnesium levels?
What effect does Aldosterone have on plasma magnesium levels?
How does Parathyroid Hormone (PTH) affect plasma magnesium levels?
How does Parathyroid Hormone (PTH) affect plasma magnesium levels?
What is a major cause of hypermagnesemia according to the text?
What is a major cause of hypermagnesemia according to the text?
What are symptoms associated with hypermagnesemia according to the text?
What are symptoms associated with hypermagnesemia according to the text?
Study Notes
Hypomagnesemia
- Hypomagnesemia is not associated with alkalosis
- Main treatment approach for hypomagnesemia is magnesium supplementation
- Diuretics, proton pump inhibitors, and aminoglycosides can contribute to the development of hypomagnesemia
Magnesium Toxicity
- People with kidney disease have a higher risk of magnesium toxicity due to impaired excretion
- A sign of magnesium toxicity is cardiac arrest
- In the body, magnesium is primarily distributed in bones (50-60%) and muscles (20-30%)
Hormonal Effects
- Aldosterone increases plasma magnesium levels by decreasing magnesium excretion
- Parathyroid Hormone (PTH) decreases plasma magnesium levels by increasing magnesium excretion
Hypermagnesemia
- A major cause of hypermagnesemia is excessive magnesium intake, especially in individuals with kidney disease
- Symptoms associated with hypermagnesemia include hypotension, respiratory depression, and cardiac arrest
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Description
Learn about how magnesium absorption works in the body and how magnesium homeostasis is maintained through the roles of the intestine, bone, and kidneys. Discover the distribution of magnesium in the body and the significance of its storage and excretion processes.
