Macrophage Activation and Tissue Response
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Questions and Answers

What is the primary effect of macrophages activated by the classical pathway on the inflammatory response?

  • Regenerative effect
  • Immune suppressive effect
  • Pro-inflammatory effect (correct)
  • Anti-inflammatory effect
  • What type of tissue is formed that includes fibroblasts, a loose extracellular matrix, new capillaries, and inflammatory cells?

  • Granulation tissue (correct)
  • Fibrous connective tissue
  • Adipose tissue
  • Scar tissue
  • What occurs when there is a mild, superficial injury to tissue?

  • Apoptosis
  • Healing with fibrous tissue
  • Regeneration (correct)
  • Necrosis
  • What is the effect of macrophages activated by the alternative pathway on the inflammatory response?

    <p>Anti-inflammatory effect</p> Signup and view all the answers

    What type of tissue repair is characterized by scar formation following an injury?

    <p>Fibrosis</p> Signup and view all the answers

    Study Notes

    Macrophage Activation & Inflammatory Response

    • Classically activated macrophages promote inflammation.

    • Alternatively activated macrophages suppress inflammation.

    Tissue Repair

    • Granulation tissue is composed of fibroblasts, loose extracellular matrix, new capillaries, and inflammatory cells.

    • Superficial injuries often heal through regeneration, where damaged tissue is replaced with identical tissue.

    • Severe injuries typically heal via scar formation, resulting in the formation of fibrous connective tissue.

    Granulomatous Inflammation

    • Granulomatous inflammation is characterized by the formation of granulomas, which are clusters of epithelioid cells, giant cells, and T lymphocytes.

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    Description

    This quiz covers the roles of macrophages in inflammation and tissue repair. You'll explore classically and alternatively activated macrophages, the process of granulation tissue formation, and the characteristics of granulomatous inflammation. Test your knowledge on how different injuries heal and the significance of macrophages in these processes.

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