Cell metabolism

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69 Questions

Which process breaks down large sugar molecules into smaller sugar molecules?

Hydrolysis

What are the smaller molecules produced by hydrolysis absorbed through?

Both A and C

Which stage of catabolism occurs intracellularly and does not use oxygen?

Anaerobic respiration

What molecule is produced in the last step of catabolism and is used in aerobic respiration?

Acetyl-CoA

What is the opposite of hydrolysis?

Dehydration synthesis

What are enzymes?

Catalysts

Which enzyme breaks down proteins?

Proteinase

Lipid metabolism

Lipolysis and betaoxidation

What are the three stages of catabolic metabolism?

Hydrolysis, anaerobic respiration, aerobic respiration

Where does hydrolysis occur in the cell?

Lumen of GI tract

Which process of cellular respiration occurs in the cytoplasm of cells?

Anaerobic respiration

What is the role of enzymes in cell metabolism?

To facilitate metabolic reactions

Which type of metabolism involves assembling new molecules and building large molecules using stored energy?

Anabolism

Protein catabolism

Deamination and transamination

Which molecule is made up of chains of nucleotides?

Nucleic acids

During which phase of mitosis does DNA replication occur?

Interphase

What is the role of DNA polymerase in DNA replication?

It forms new DNA molecules

What is the genetic code made up of in DNA?

Sequence of Nitrogenous bases

What are the subunits of DNA molecules called?

Genes

Where can protein catabolism occur?

Mitochondria

What is the process that breaks down large molecules by adding water?

Hydrolysis

Where does protein anabolism/synthesis begin?

Nucleus

Protein synthesis

Transcription and translation

Which metabolic pathway involves the breakdown of glycogen, glycerol, or propionate?

Carbohydrate metabolism

Primary controller of lipid metabolism

Liver

Which stage of cellular respiration produces the majority of ATP for the cell?

The Electron Transport System

What is the primary responsibility of the liver in lipid metabolism?

Lipolysis and beta-oxidation

Why do lipids contain more cellular energy than carbs or protein

Higher # of C-H bonds, and energy is stored in bonds between the atoms

What is the process by which proteins are broken down into amino acids?

Deamination and transamination

Catabolism

Breakdown of nutrients and produce energy

Anabolism

Assemble new molecules and use stored energy

Molecular reactions are initiated and controlled by formation and use of specialized proteins called

Enzymes

The process by which glucose is initially converted to G6P via phosphorylation then broken down further into pyruvate occurs in

The cytosol

1st stage of catabolism

Hydrolysis

Breakdown of larger molecules into smaller ones (produces energy) from carbohydrates (CHO), fats, and proteins

Catabolic metabolism

[HYDROLYSIS] _______ -> __________ + ______ = +

Polysaccharide -> Disaccharide + Water = 1 Monosaccharide + 1 Monosaccharide

[Hydrolysis] Protein -> ____

Amino acids

Nucleic acids -> _________

Nucleotides

[Hydrolysis] Fat -> _____

Both B and C

One water molecule is used each time a nutrient molecule is broken down

Hydrolysis

Large sugar molecule can be broken down (______) into smaller sugar molecules

Hydrolysis

The smaller molecules produced by hydrolysis are absorbed through special absorptive cells called enterocytes that line the _________ and transported to other parts of the body via ________

Small intestines, circulatory and lymphatic systems

Amino acids, glucose, glycerol and fatty acids enter the cell and are further ___________ in the __________

Catabolized, cytoplasm

[Anaerobic respiration] Produces _________ -> converted to _______ -> transported to the ________ where it is used in the last step of catabolism

Pyruvate -> acetyl-CoA-> mitochondria

________ enters the __________ to be used in aerobic respiration

Acetyl-CoA, Kreb's cycle

Cell uses energy in the form of ATP to manufacture substances and perform many vital functions

Anabolic metabolism

Simple sugars assembled to form chains of polysaccharides

Dehydration synthesis

Glycerol and fat are connected to form fat molecules

Dehydration synthesis

Chains of amino acids are assembled to form proteins

Dehydration synthesis

Compartments created within or on the surface of organelles (mitochondria, ER, ribosomes) ___________________

Isolate and allow chemical reactions between molecules to take place

Energy is needed to initiate chemical reactions

Energy of activation

Substances that speed up reactions by lowering the energy of activation

Both A and C

Needed to complete the shape of a binding site or to stabilize the enzyme-substrate complex

Cofactors

Non-protein organic substances can act as ______ but are called _________

Cofactors, coenzymes

Complex series of biochemical steps that must occur in a particular sequence, each step involves an enzyme specific for that particular step

Metabolic pathways

Anaerobic respiration

Glycolysis

Requires use of 2 ATP molecules and 2 NAD molecules for every molecule of glucose that is metabolized

Both B and C

Used to provide the energy to fuel metabolic functions such as absorption, secretion, excretion, mechanical work, growth and repair

Carbohydrate metabolism

Occurs in the inner mitochondrial membrane

Electron transport chain

Can remove lipids from the blood and alter their structures

Liver

Microtubules, hair, collagen

Structural proteins

Insulin, other hormones

Regulatory proteins

Actin and myosin

Contractile proteins

Chains of amino acids linked by peptide bonds

Proteins

Essential amino acid for the feline

Taurine

Occurs in most tissues but is especially important in intestine, kidney liver, brain and skeletal muscle

Protein catabolism

Protein synthesis begins in the nucleus, intructions within the DNA are transferred to mRNA () using RNA polymerase and carried to cytoplasm where aa are assembled into proteins () on ribosomes (which are composed of protein and ribosomal RNA (rRNA) with help of transfer RNA (tRNA))

Transcription, translation

Amine group removed and becomes ammonia in liver -> converted to urea -> excreted in urine

Deamination

Proteins from food are hydrolized into aa by enzymes, proteases and peptidases, in the GI tract ->liver via hepatic portal system; liver controls subsequent release and use of aa in nonhepatic tissues

Protein anabolism

Study Notes

Metabolism of Carbohydrates, Lipids, and Proteins

  • Cofactors, such as iron, zinc, copper, magnesium, calcium, and potassium, are needed to complete the shape of a binding site in enzymes.
  • Nonprotein organic substances called coenzymes, often derived from vitamins, can also act as cofactors.
  • Metabolic pathways are complex series of biochemical steps that must occur in a particular sequence, with each step involving a specific enzyme.
  • Carbohydrate metabolism is used to provide energy for various metabolic functions and can be obtained from the diet or through the breakdown of glycogen, glycerol, or propionate.
  • Anaerobic respiration, also known as glycolysis, is the process by which glucose is converted to pyruvate in the cytosol without requiring oxygen.
  • Pyruvate is further degraded in the mitochondria as part of aerobic respiration, also known as cellular respiration, which produces ATP for the cell.
  • Cellular respiration occurs in two stages: the Kreb's Cycle (Citric Acid Cycle) and the Electron Transport System.
  • The Kreb's Cycle generates energy in the form of ATP, FADH2, and NADH molecules, while CO2 is produced as a byproduct.
  • The Electron Transport System produces the majority of ATP for the cell by utilizing FADH2 and NADH.
  • Lipids are molecules composed of carbon, hydrogen, and oxygen, and are insoluble in water but dissolve easily in other lipids or organic solvents.
  • The liver is primarily responsible for lipid metabolism, including lipolysis and beta-oxidation, which converts fatty acids into acetyl-CoA or ketone bodies.
  • Proteins have various functions and structures, including structural, regulatory, contractile, transport, and storage proteins.
  • Protein metabolism involves the hydrolysis of proteins into amino acids, which are then used for protein synthesis or energy production through deamination and transamination processes.

Test your knowledge of carbohydrate, lipid, and protein metabolism with this quiz! Learn about the essential cofactors and coenzymes involved, the complex pathways, and the breakdown processes of each macronutrient. Challenge yourself with questions on glycolysis, the Kreb's Cycle, and the Electron Transport System. Explore the liver's role in lipid metabolism and understand protein hydrolysis and synthesis.

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