Macrocytic Anemias Overview
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Questions and Answers

What primary factors cause macrocytosis in megaloblastic anemias?

  • Vitamin B12 or folate deficiency (correct)
  • Iron deficiency and dehydration
  • Electrolyte imbalance and liver disease
  • Chronic inflammation and infection
  • Which of the following is not considered a drug that can cause macrocytosis?

  • Zidovudine
  • Hydroxyurea
  • Methotrexate
  • Acetaminophen (correct)
  • What type of anemia is characterized by macrocytosis due to abnormal DNA metabolism?

  • Megaloblastic anemia (correct)
  • Aplastic anemia
  • Hemolytic anemia
  • Sideroblastic anemia
  • Which vitamin deficiency is primarily associated with megaloblastic anemias?

    <p>Vitamin B12</p> Signup and view all the answers

    What is the main classification of macrocytic anemias?

    <p>Megaloblastic and nonmegaloblastic</p> Signup and view all the answers

    Study Notes

    Macrocytic Anemias

    • Macrocytic anemias are categorized into megaloblastic and nonmegaloblastic types.
    • Megaloblastic anemias result in macrocytosis.
    • Macrocytosis in megaloblastic anemias stems from abnormal DNA metabolism due to vitamin B12 or folate deficiency.
    • Various drugs can also cause macrocytosis, including hydroxyurea, zidovudine, cytosine arabinoside, methotrexate, azathioprine, 6-mercaptopurine, and cladribine.

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    Description

    This quiz covers macrocytic anemias, focusing on their classification into megaloblastic and nonmegaloblastic types. Learn about the causes of macrocytosis, specifically the impact of vitamin B12 and folate deficiencies, as well as the influence of various medications. Test your knowledge on this key aspect of hematology.

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