Machine Learning in 3D Chromatin Conformation Analysis

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What method did Xu et al. develop for constructing patient-specific enhancer-gene edges?

DGTAC, a computational method

What type of data does DGTAC utilize as input for constructing enhancer-gene edges?

ATAC-seq and RNA-seq

What type of cancer-specific connections can DGTAC reveal?

Enhancer-gene connections for cancer genes

How can the enhancer-gene connections predicted by DGTAC be validated?

<p>Using CRISPRi</p> Signup and view all the answers

What is the primary advantage of DGTAC in terms of sample availability?

<p>Suitable for use with limited samples obtained from patient biopsies</p> Signup and view all the answers

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