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Lymphoma Classification and Grading

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Questions and Answers

Which infection is associated with the development of gastric lymphoma?

Human herpes virus 8 (HHV8)

Epstein-Barr virus (EBV)

Helicobacter pylori (correct)

HTLV infection

Which chromosome translocation is associated with dysregulated expression of the BCL-2 gene product in follicular lymphoma?

t(11:14)

t(14:18) (correct)

t(9:22)

t(8:14)

In which immunodeficiency state can lymphoma be a late manifestation?

HIV infection (correct)

Malaria infection

Influenza infection

Hepatitis B infection

What is the percentage of B-cell origin in Non-Hodgkin lymphoma (NHL)?

70% Signup and view all the answers

What is the median age for Non-Hodgkin lymphoma (NHL) incidence?

65-70 years Signup and view all the answers

Which of the following is NOT a feature of Non-Hodgkin lymphoma?

Associated with Helicobacter pylori infection Signup and view all the answers

What is the main causative abnormality described for lymphomas?

't(14:18)' translocation Signup and view all the answers

What does the t(14:18) translocation do in follicular lymphoma?

Inhibits apoptotic cell death Signup and view all the answers

What is NOT associated with specific chromosome lesions in some lymphomas?

t(9:22) translocation in t(14:18) translocation results in the dysregulated expression of the BCL-2 gene product which inhibits apoptotic cell death Signup and view all the answers

Lymphoma Classification and Grading

Choose a study mode

Podcast

Questions and Answers

Which infection is associated with the development of gastric lymphoma?

Which chromosome translocation is associated with dysregulated expression of the BCL-2 gene product in follicular lymphoma?

In which immunodeficiency state can lymphoma be a late manifestation?

What is the percentage of B-cell origin in Non-Hodgkin lymphoma (NHL)?

What is the median age for Non-Hodgkin lymphoma (NHL) incidence?

Which of the following is NOT a feature of Non-Hodgkin lymphoma?

What is the main causative abnormality described for lymphomas?

What does the t(14:18) translocation do in follicular lymphoma?

What is NOT associated with specific chromosome lesions in some lymphomas?

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