Hodgkin's and Non-Hodgkin's Lymphoma Quiz

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Questions and Answers

Which is the most common world cancer?

Oral squamous cell carcinoma (correct)

Prostate cancer

Leukemia

Breast cancer

What are considered high risk sites for oral squamous cell carcinoma?

Lateral surface of the tongue and soft palate (correct)

Ventral surface of the tongue and floor of the mouth

Buccal mucosa and labial mucosa

Gums and hard palate

What is the most common cause of oral squamous cell carcinoma in men?

Age

Genetic factors

Alcohol use

Tobacco use (correct)

Apart from the lateral surface of the tongue and soft palate, where else can squamous cell carcinoma arise?

All of the above Signup and view all the answers

Who is considered at increased risk for developing oral squamous cell carcinoma?

Women who use tobacco Signup and view all the answers

What type of epithelium does the surface mucosa arise from?

Stratified squamous epithelium Signup and view all the answers

What is a high-risk site for the appearance of gingival carcinomas?

Lateral tongue Signup and view all the answers

How can squamous cell carcinoma present intravenously?

White lesion Signup and view all the answers

What is the crucial step for the final diagnosis of squamous cell carcinoma?

Biopsy Signup and view all the answers

What is the classification of leukemia based on clinical course?

Acute and chronic Signup and view all the answers

What are the signs and symptoms of leukemia related to decreased blood cell counts?

Susceptibility to infection Signup and view all the answers

What oral manifestation can be associated with leukemia?

Diffuse gingival enlargement Signup and view all the answers

What can leukemia cause in the oral cavity?

Diffuse enlargement of the gingiva and hemorrhagic changes Signup and view all the answers

How can leukemia cells affect the jawbones?

Infiltrate jawbones, mimicking periodontal inflammatory lesions Signup and view all the answers

What infections are leukemia patients at an increased risk of developing?

Candidiasis and recurrent herpes infections Signup and view all the answers

How is leukemia diagnosed?

Peripheral blood analysis, bone marrow biopsy, histopathology examination, and immunohistochemical, cytogenetic, and molecular studies Signup and view all the answers

What is the classic presentation for leukemia in the oral cavity?

Diffuse gingival enlargement, which is soft on palpation Signup and view all the answers

Where does Hodgkin's lymphoma almost always begin?

In the lymph nodes, causing persistent non-tender enlargement Signup and view all the answers

What is the most common type of non-Hodgkin's lymphoma in the oral cavity?

Diffuse large B-cell lymphoma Signup and view all the answers

How are oral lymphoma and leukemia different in terms of presentation?

Oral lymphoma presents as a non-tender swelling, while leukemia presents with tender swelling Signup and view all the answers

How is the diagnosis of oral lymphoma confirmed?

Tissue biopsy and additional pathology work Signup and view all the answers

What can oral lymphoma in the bone cause if left untreated?

Cortical expansion, perforation, and tooth mobility Signup and view all the answers

What are the common locations for diffuse non-tender enlargement in oral lymphoma?

Palate, gingiva, and vestibule Signup and view all the answers

What does the microscopic examination of oral lymphoma reveal?

Atypical lymphocytic cells packed together with minimal cytoplasm and hyperchromatic nuclei Signup and view all the answers

What percentage of cells in the enlarged lymph node are made up of Reed-Sternberg cells in classic Hodgkin's lymphoma?

0.1 to 2% Signup and view all the answers

Which lymph node group is affected in 70-75% of classic Hodgkin's lymphoma cases?

Cervical and clavicle Signup and view all the answers

In which age groups does Hodgkin's lymphoma show a bimodal peak in diagnosis?

Teenagers and young adults (15-35) and older individuals (over 50) Signup and view all the answers

What are the common signs presented by patients with Hodgkin's lymphoma?

Painless enlargement of affected lymph nodes, weight loss, fever, night sweats, and generalized itching Signup and view all the answers

What is crucial for treatment planning and estimating prognosis in Hodgkin's lymphoma?

Staging Signup and view all the answers

Where can non-Hodgkin's lymphoma originate?

Lymph node or extranodal site Signup and view all the answers

Study Notes

Hodgkin's and Non-Hodgkin's Lymphoma: Key Points

In classic Hodgkin's lymphoma, atypical neoplastic cells called Reed-Sternberg cells make up only 0.1 to 2% of the cells in the enlarged lymph node.
Hodgkin's lymphoma can have a strong association with Epstein-Barr virus infection.
It can affect any lymph node group, with 70-75% of cases affecting the cervical and clavicle lymph nodes, 5-10% affecting the axillary and mediastinal lymph nodes, and less than 5% involving the inguinal or abdominal lymph nodes.
Hodgkin's lymphoma shows a bimodal peak in age at diagnosis, with one group being teenagers and young adults (15-35) and another being older individuals (over 50), with a male predominance.
Patients with Hodgkin's lymphoma present with signs such as persistent painless enlargement of affected lymph nodes, weight loss, fever, night sweats, and generalized itching.
Staging of Hodgkin's lymphoma is crucial for treatment planning and estimating prognosis, with category A having a better prognosis compared to category B where additional symptoms are present.
Diagnosis of Hodgkin's lymphoma involves history, physical examination, microscopic examination of affected lymph nodes, immunohistochemical studies, and additional imaging studies to determine the extent of spread.
Treatment for Hodgkin's lymphoma depends on the stage of involvement, with options including radiation therapy or a combination of radiation and chemotherapy.
Non-Hodgkin's lymphoma is a malignant lymphoma that can originate in a lymph node or, rarely, in an extranodal site such as the oral cavity.
In non-Hodgkin's lymphoma, affected lymph nodes show persistent non-tender enlargement, become fused to underlying tissues as the disease progresses, and spread to other lymph node groups and tissues.
The classification of non-Hodgkin's lymphoma has evolved, and the current US classification takes into consideration microscopic presentation, immunohistochemical analysis, and cytogenetic alterations.
Non-Hodgkin's lymphoma can affect any age group but is more common in adults, presenting as slowly enlarging, non-tender masses in affected lymph nodes, most commonly in the cervical, axillary, or inguinal lymph nodes.

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Test your knowledge about Hodgkin's and Non-Hodgkin's Lymphoma with this informative quiz. Covering key points such as histological characteristics, clinical manifestations, staging, and treatment options, this quiz will help reinforce your understanding of these two types of lymphomas.