Podcast
Questions and Answers
Which is the most common world cancer?
Which is the most common world cancer?
- Oral squamous cell carcinoma (correct)
- Prostate cancer
- Leukemia
- Breast cancer
What are considered high risk sites for oral squamous cell carcinoma?
What are considered high risk sites for oral squamous cell carcinoma?
- Lateral surface of the tongue and soft palate (correct)
- Ventral surface of the tongue and floor of the mouth
- Buccal mucosa and labial mucosa
- Gums and hard palate
What is the most common cause of oral squamous cell carcinoma in men?
What is the most common cause of oral squamous cell carcinoma in men?
- Age
- Genetic factors
- Alcohol use
- Tobacco use (correct)
Apart from the lateral surface of the tongue and soft palate, where else can squamous cell carcinoma arise?
Apart from the lateral surface of the tongue and soft palate, where else can squamous cell carcinoma arise?
Who is considered at increased risk for developing oral squamous cell carcinoma?
Who is considered at increased risk for developing oral squamous cell carcinoma?
What type of epithelium does the surface mucosa arise from?
What type of epithelium does the surface mucosa arise from?
What is a high-risk site for the appearance of gingival carcinomas?
What is a high-risk site for the appearance of gingival carcinomas?
How can squamous cell carcinoma present intravenously?
How can squamous cell carcinoma present intravenously?
What is the crucial step for the final diagnosis of squamous cell carcinoma?
What is the crucial step for the final diagnosis of squamous cell carcinoma?
What is the classification of leukemia based on clinical course?
What is the classification of leukemia based on clinical course?
What are the signs and symptoms of leukemia related to decreased blood cell counts?
What are the signs and symptoms of leukemia related to decreased blood cell counts?
What oral manifestation can be associated with leukemia?
What oral manifestation can be associated with leukemia?
What can leukemia cause in the oral cavity?
What can leukemia cause in the oral cavity?
How can leukemia cells affect the jawbones?
How can leukemia cells affect the jawbones?
What infections are leukemia patients at an increased risk of developing?
What infections are leukemia patients at an increased risk of developing?
How is leukemia diagnosed?
How is leukemia diagnosed?
What is the classic presentation for leukemia in the oral cavity?
What is the classic presentation for leukemia in the oral cavity?
Where does Hodgkin's lymphoma almost always begin?
Where does Hodgkin's lymphoma almost always begin?
What is the most common type of non-Hodgkin's lymphoma in the oral cavity?
What is the most common type of non-Hodgkin's lymphoma in the oral cavity?
How are oral lymphoma and leukemia different in terms of presentation?
How are oral lymphoma and leukemia different in terms of presentation?
How is the diagnosis of oral lymphoma confirmed?
How is the diagnosis of oral lymphoma confirmed?
What can oral lymphoma in the bone cause if left untreated?
What can oral lymphoma in the bone cause if left untreated?
What are the common locations for diffuse non-tender enlargement in oral lymphoma?
What are the common locations for diffuse non-tender enlargement in oral lymphoma?
What does the microscopic examination of oral lymphoma reveal?
What does the microscopic examination of oral lymphoma reveal?
What percentage of cells in the enlarged lymph node are made up of Reed-Sternberg cells in classic Hodgkin's lymphoma?
What percentage of cells in the enlarged lymph node are made up of Reed-Sternberg cells in classic Hodgkin's lymphoma?
Which lymph node group is affected in 70-75% of classic Hodgkin's lymphoma cases?
Which lymph node group is affected in 70-75% of classic Hodgkin's lymphoma cases?
In which age groups does Hodgkin's lymphoma show a bimodal peak in diagnosis?
In which age groups does Hodgkin's lymphoma show a bimodal peak in diagnosis?
What are the common signs presented by patients with Hodgkin's lymphoma?
What are the common signs presented by patients with Hodgkin's lymphoma?
What is crucial for treatment planning and estimating prognosis in Hodgkin's lymphoma?
What is crucial for treatment planning and estimating prognosis in Hodgkin's lymphoma?
Where can non-Hodgkin's lymphoma originate?
Where can non-Hodgkin's lymphoma originate?
Study Notes
Hodgkin's and Non-Hodgkin's Lymphoma: Key Points
- In classic Hodgkin's lymphoma, atypical neoplastic cells called Reed-Sternberg cells make up only 0.1 to 2% of the cells in the enlarged lymph node.
- Hodgkin's lymphoma can have a strong association with Epstein-Barr virus infection.
- It can affect any lymph node group, with 70-75% of cases affecting the cervical and clavicle lymph nodes, 5-10% affecting the axillary and mediastinal lymph nodes, and less than 5% involving the inguinal or abdominal lymph nodes.
- Hodgkin's lymphoma shows a bimodal peak in age at diagnosis, with one group being teenagers and young adults (15-35) and another being older individuals (over 50), with a male predominance.
- Patients with Hodgkin's lymphoma present with signs such as persistent painless enlargement of affected lymph nodes, weight loss, fever, night sweats, and generalized itching.
- Staging of Hodgkin's lymphoma is crucial for treatment planning and estimating prognosis, with category A having a better prognosis compared to category B where additional symptoms are present.
- Diagnosis of Hodgkin's lymphoma involves history, physical examination, microscopic examination of affected lymph nodes, immunohistochemical studies, and additional imaging studies to determine the extent of spread.
- Treatment for Hodgkin's lymphoma depends on the stage of involvement, with options including radiation therapy or a combination of radiation and chemotherapy.
- Non-Hodgkin's lymphoma is a malignant lymphoma that can originate in a lymph node or, rarely, in an extranodal site such as the oral cavity.
- In non-Hodgkin's lymphoma, affected lymph nodes show persistent non-tender enlargement, become fused to underlying tissues as the disease progresses, and spread to other lymph node groups and tissues.
- The classification of non-Hodgkin's lymphoma has evolved, and the current US classification takes into consideration microscopic presentation, immunohistochemical analysis, and cytogenetic alterations.
- Non-Hodgkin's lymphoma can affect any age group but is more common in adults, presenting as slowly enlarging, non-tender masses in affected lymph nodes, most commonly in the cervical, axillary, or inguinal lymph nodes.
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Description
Test your knowledge about Hodgkin's and Non-Hodgkin's Lymphoma with this informative quiz. Covering key points such as histological characteristics, clinical manifestations, staging, and treatment options, this quiz will help reinforce your understanding of these two types of lymphomas.
