16 Questions
Where does hematopoiesis occur initially during fetal development?
In the yolk sac
What is the primary function of red bone marrow?
Production of red blood cells
Which organ is responsible for storing fat and certain stem cells?
Bone marrow
Which organ is NOT classified as a primary lymphoid organ?
Spleen
What are the two types of bone marrow mentioned in the text?
Red and yellow bone marrow
Where does B cell maturation occur?
Bone marrow
Where does hematopoiesis take place mostly by puberty?
Sternum
What is the red marrow in bones composed of?
Blood-filled sinusoids and blood cell precursors
Where do blood cell precursors mature before entering the vascular circulation?
In the sinusoidal basement membrane
What happens when there is an exceptional demand for production of new blood cells?
The liver and spleen become sites of extramedullary hematopoiesis
What is the function of Hematopoietic Stem Cells (HSCs)?
They can differentiate into all types of blood cells
How are HSCs identified?
By the absence of lineage-specific markers expressed in mature cells
What roles do Innate Lymphoid Cells (ILCs) play?
Immune defense against microbes, regulation of adaptive immunity, tissue remodeling, and repair
What happens to the thymus after puberty?
It involutes so that it is not detectable in adults
What is the function of the thymus gland?
Maturation of T lymphocytes
What is the composition of red marrow in bones?
Spongelike reticular framework with a network of blood-filled sinusoids lined by endothelial cells and clusters of blood cell precursors
This quiz covers the primary and secondary lymphoid organs of the immune system, including the bone marrow and the thymus. It also discusses the functions of these organs in the immune response.
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