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Questions and Answers
Where does the greater part of lymphocyte development in mammals occur?
Where does the greater part of lymphocyte development in mammals occur?
- Liver
- Bone marrow (correct)
- Peripheral lymphoid tissues
- Thymus
How are T-cell numbers maintained in mature individuals?
How are T-cell numbers maintained in mature individuals?
- Through migration from the bone marrow
- By migration to peripheral lymphoid tissues
- Through division of mature T cells outside of the central lymphoid organs (correct)
- By continuous production in the thymus
What serves as a signal for a cell to progress to the next stage of development during lymphocyte development?
What serves as a signal for a cell to progress to the next stage of development during lymphocyte development?
- Appearance of functional features
- Successful gene rearrangement leading to protein chain production (correct)
- T-cell development
- Migration to peripheral lymphoid tissues
Which type of T cells have two distinct lineages with different types of T-cell receptor?
Which type of T cells have two distinct lineages with different types of T-cell receptor?
Where are new B cells continually produced, even in adults?
Where are new B cells continually produced, even in adults?
In lymphocyte development, what specialized environments play a crucial role in providing signals for successful execution of the intrinsic developmental program?
In lymphocyte development, what specialized environments play a crucial role in providing signals for successful execution of the intrinsic developmental program?
What is the significance of the assembly of V, D, and J gene segments in lymphocyte differentiation?
What is the significance of the assembly of V, D, and J gene segments in lymphocyte differentiation?
What defines the different stages of lymphocyte development?
What defines the different stages of lymphocyte development?
Why is not every gene rearrangement event successful in producing a complete in-frame DNA sequence?
Why is not every gene rearrangement event successful in producing a complete in-frame DNA sequence?
What is the role of productive rearrangements in lymphocyte development?
What is the role of productive rearrangements in lymphocyte development?
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