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Questions and Answers
What is the main cause of localized obstructive oedema in the area due to lymphatic permeation?
What is the main cause of localized obstructive oedema in the area due to lymphatic permeation?
How does spread from one nodal group to distant groups occur?
How does spread from one nodal group to distant groups occur?
How do some types of tumor cells grow within the lumen of the lymphatic vessels?
How do some types of tumor cells grow within the lumen of the lymphatic vessels?
What causes the node to become enlarged, firm, and fixed?
What causes the node to become enlarged, firm, and fixed?
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Which mechanism causes hematogenous spread as malignant cells reach the venous circulation?
Which mechanism causes hematogenous spread as malignant cells reach the venous circulation?
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Study Notes
Localized Obstructive Edema
- Localized obstructive edema commonly arises due to lymphatic permeation, where lymphatic vessels become obstructed or infiltrated by tumor cells, leading to fluid accumulation in tissues.
Spread from Nodal Groups
- Tumor cells can spread from one nodal group to distant lymph nodes through the lymphatic system, utilizing the interconnected network of lymphatic vessels which can transport cells across considerable distances.
Tumor Cells in Lymphatic Vessels
- Certain tumor cells have the ability to grow within the lumen of lymphatic vessels by exploiting the vessel structure, allowing them to bypass local immune responses and travel through the lymphatic system.
Enlarged Lymph Nodes
- Lymph nodes may become enlarged, firm, and fixed due to the infiltration of malignancies, resulting in increased lymphatic pressure, or by reactive hyperplasia due to immune response, causing the nodes to harden and become adherent to surrounding tissues.
Hematogenous Spread Mechanism
- Hematogenous spread, where malignant cells reach the bloodstream, occurs through invasion into venous circulation. Tumor cells can penetrate blood vessels directly or via pre-existing vascular networks, enabling them to travel throughout the body.
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Description
Test your knowledge of lymphatic embolism morphology with this quiz. Identify the gross and microscopic characteristics of nodal involvement in lymphatic embolism and understand the spread of metastatic deposits through the lymphatic system.
