Lung Volumes and Capacities Quiz
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Questions and Answers

What primarily causes the pressure volume hysteresis in the lungs during inhalation and exhalation?

  • Lung elasticity differential
  • Respiratory muscle contraction mechanics
  • Airway resistance variations
  • Surface tension of alveolar fluid (correct)

What happens to the intermolecular forces during the process of inhalation?

  • They become strong due to close molecular proximity. (correct)
  • They increase, making inhalation easier.
  • They decrease, allowing for significant volume change.
  • They remain constant throughout the breathing cycle.

How does the volumetric change during exhalation compare to that during inhalation?

  • There is a significant change in volume during inhalation.
  • Volumetric change is equal in both inhalation and exhalation.
  • There is a greater volumetric change during exhalation. (correct)
  • Volumetric change is negligible during both processes.

Which statement best describes the compliance of the lungs during the two phases of breathing?

<p>Exhalation has higher compliance compared to inhalation. (D)</p> Signup and view all the answers

What does the slope of the pressure volume curve represent in the context of lung physiology?

<p>The compliance of the lungs (D)</p> Signup and view all the answers

What is the pressure inside the alveoli when the pleural pressure is +20?

<p>+35 (D)</p> Signup and view all the answers

What occurs at the equal pressure point in a healthy respiratory system?

<p>Airway pressure equals pleural pressure (B)</p> Signup and view all the answers

In healthy lungs, where does the equal pressure point occur?

<p>In the bronchi (B)</p> Signup and view all the answers

What happens to the equal pressure point during forced exhalation in patients with diseased lungs?

<p>It moves toward the alveoli (C)</p> Signup and view all the answers

What is the primary effect of increased lung compliance on the functional residual capacity (FRC)?

<p>It increases the FRC. (B)</p> Signup and view all the answers

What condition may cause airway collapse during expiration due to high pleural pressure?

<p>Bronchitis (A), Emphysema (B)</p> Signup and view all the answers

Why do patients with COPD engage in slow exhalation?

<p>To prevent high pleural pressures (A)</p> Signup and view all the answers

Which condition is associated with decreased lung compliance?

<p>Pulmonary edema (B)</p> Signup and view all the answers

What is the effect of pursed lips on airway pressure during exhalation in patients with lung diseases?

<p>It creates an obstruction that increases pressure (A)</p> Signup and view all the answers

During a forced exhalation, what happens to the pleural pressure?

<p>It can become positive. (C)</p> Signup and view all the answers

How does non-compliance of the lungs affect the pressure-volume relationship compared to compliant lungs?

<p>It leads to lower volume changes for the same pressure. (A)</p> Signup and view all the answers

What is a common characteristic of emphysema as it relates to alveolar pressure?

<p>Loss of elastic recoil (D)</p> Signup and view all the answers

What physiological mechanism increases lung compliance in older patients?

<p>Structural changes in lung tissue (C)</p> Signup and view all the answers

What happens to airway pressure in patients with bronchitis during forced exhalation?

<p>It decreases more rapidly than normal (C)</p> Signup and view all the answers

What is one consequence of the pressure volume relationship changing in non-compliant lungs?

<p>Decreased inspiratory capacity (C)</p> Signup and view all the answers

What term describes the phenomenon where a substance’s properties depend on its history?

<p>Hysteresis (D)</p> Signup and view all the answers

What characterizes the pressure in the pleural space during quiet breathing?

<p>It is always negative. (C)</p> Signup and view all the answers

Which alveolar pressure is expected during a forced exhalation with a pleural pressure of +20 mmHg?

<p>+35 mmHg (D)</p> Signup and view all the answers

What happens to lung volume when no pressure is applied to the airways?

<p>The lungs collapse completely. (D)</p> Signup and view all the answers

In a healthy respiratory system, what significance does cartilage have in the airway?

<p>Prevents airway collapse (A)</p> Signup and view all the answers

How does loss of elastic recoil impact pleural and alveolar pressures in emphysema?

<p>It leads to alveolar pressure being lower than expected (A)</p> Signup and view all the answers

What prevents the lungs from collapsing completely when they're inside the body?

<p>The negative pressure created by the chest wall. (D)</p> Signup and view all the answers

Which of the following diseases is characterized by increased lung compliance?

<p>Emphysema (A)</p> Signup and view all the answers

What happens to the FRC in patients with diseases that cause the lungs to become stiff?

<p>It decreases. (B)</p> Signup and view all the answers

At the functional residual capacity (FRC), which forces are in equilibrium?

<p>Tendency of the lungs to collapse and tendency of the chest to expand. (D)</p> Signup and view all the answers

What distinguishes the equal pressure point in healthy lungs from that in diseased lungs?

<p>It is closer to the alveoli in diseased lungs (A)</p> Signup and view all the answers

In which scenario is the equal pressure point significant?

<p>During forced exhalation. (C)</p> Signup and view all the answers

How is lung compliance defined?

<p>As the change in volume per unit change in pressure. (D)</p> Signup and view all the answers

What physiological change occurs during forced exhalation that leads to positive pleural pressure?

<p>Contraction of abdominal muscles (D)</p> Signup and view all the answers

Which of the following statements about the relationship between pressure and volume in the lungs is true?

<p>The pressure-volume relationship differs when lungs are in and out of the body. (A)</p> Signup and view all the answers

What is a typical finding in patients with emphysema related to lung volumes?

<p>Increased total lung capacity (B)</p> Signup and view all the answers

What is the significance of the maximum lung volume reached when pressure is applied?

<p>It reflects the lung's elastic limit. (C)</p> Signup and view all the answers

How does the chest wall behave when no pressure is applied?

<p>It exerts a natural outward spring force. (C)</p> Signup and view all the answers

What effect does the presence of surfactant have on lung compliance?

<p>Increases lung compliance (A)</p> Signup and view all the answers

How does the pressure-volume curve of a compliant lung differ from that of a non-compliant lung?

<p>It is steeper and requires less pressure for the same volume change. (A)</p> Signup and view all the answers

What happens to lung volume if a negative pressure is applied?

<p>Lung volume decreases. (A)</p> Signup and view all the answers

What does the green curve represent in the lung-pressure relationship graph?

<p>The respiratory system's overall volume-pressure relationship. (D)</p> Signup and view all the answers

Which statement best describes intrapulmonary pressure when at FRC?

<p>It equals atmospheric pressure. (B)</p> Signup and view all the answers

What defines the concept of functional residual capacity (FRC)?

<p>The amount of air remaining after maximal exhalation. (C)</p> Signup and view all the answers

What role does the chest wall play in respiration?

<p>Its pressure directly determines lung volume. (D)</p> Signup and view all the answers

What happens to the alveolar pressure during exhalation?

<p>It becomes positive, causing air to flow out. (C)</p> Signup and view all the answers

How does the intrapleural pressure change during inhalation?

<p>It becomes more negative. (B)</p> Signup and view all the answers

What is the transpulmonary pressure at the end of inhalation?

<p>+0.8 (D)</p> Signup and view all the answers

What best describes the tidal volume in lung physiology?

<p>The amount of air exchanged during quiet breathing. (A)</p> Signup and view all the answers

What initiates airflow into the lungs during inhalation?

<p>Decrease in intrapleural pressure. (C)</p> Signup and view all the answers

At what intrapleural pressure do the lungs ideally start and end during quiet breathing?

<p>-5 at the start and -8 at the end. (A)</p> Signup and view all the answers

Which of the following correctly defines the expiratory reserve volume?

<p>The additional volume of air that can be forcibly exhaled after a normal exhale. (A)</p> Signup and view all the answers

What is the primary feature of inspiratory reserve volume?

<p>It represents the amount of air that can be inhaled forcefully beyond tidal volume. (D)</p> Signup and view all the answers

What physiological change occurs during exhalation regarding lung volume?

<p>The lung volume decreases as air is expelled. (D)</p> Signup and view all the answers

What is the effect of diaphragm contraction during inhalation?

<p>Air is drawn into the alveoli. (D)</p> Signup and view all the answers

Why can residual volume never be fully exhaled from the lungs?

<p>There is always a small amount of air that remains in the lungs to prevent collapse. (B)</p> Signup and view all the answers

Which pressure change indicates the onset of inhalation?

<p>Intrapleural pressure shifts to a lower negative value. (D)</p> Signup and view all the answers

Which volume would you measure if you wanted to assess the total amount of air that can be exhaled after a maximum inhalation?

<p>Vital capacity. (B)</p> Signup and view all the answers

Which statement about tidal volume, expiratory reserve volume, and inspiratory reserve volume is correct?

<p>They are involved in normal respiratory patterns during rest and exertion. (A)</p> Signup and view all the answers

How much air does the average adult inhale during a quiet breathing cycle?

<p>Half a liter. (D)</p> Signup and view all the answers

If one were to perform a forced expiration, which volume would still remain in the lungs?

<p>Residual volume. (B)</p> Signup and view all the answers

What happens to the transpulmonary pressure at the end of exhalation?

<p>It decreases to +5. (C)</p> Signup and view all the answers

During tidal breathing, when does the pressure in the alveoli become positive?

<p>At the end of exhalation. (D)</p> Signup and view all the answers

In the context of pulmonary physiology, what is the consequence of varying tidal volume?

<p>It reflects changes in the respiratory system's ability to ventilate effectively. (C)</p> Signup and view all the answers

What causes air to flow into the lungs during inhalation?

<p>Negative alveolar pressure relative to atmospheric pressure. (D)</p> Signup and view all the answers

Why is the intrapleural pressure typically always negative?

<p>To prevent lung collapse. (A)</p> Signup and view all the answers

What physiological process occurs immediately after the diaphragm relaxes?

<p>Air flows out of the lungs. (B)</p> Signup and view all the answers

What happens to the transpulmonary pressure during a pneumothorax?

<p>It becomes zero. (B)</p> Signup and view all the answers

During quiet breathing, what is the typical pressure in the intrapleural space?

<p>-5 mmHg (D)</p> Signup and view all the answers

What occurs when the intrapleural pressure becomes more negative during inhalation?

<p>Air flows into the lungs. (C)</p> Signup and view all the answers

How does atmospheric pressure relate to airflow during normal breathing?

<p>It is always higher than pulmonary pressure. (D)</p> Signup and view all the answers

What effect does relaxing the diaphragm have on intrapleural pressure?

<p>It causes intrapleural pressure to become less negative. (A)</p> Signup and view all the answers

When the pressure in the alveoli becomes positive during exhalation, what is the source of this pressure change?

<p>Relaxation of intrapleural suction force. (B)</p> Signup and view all the answers

Which condition correctly describes transpulmonary pressure?

<p>It is the difference between alveolar pressure and intrapleural pressure. (B)</p> Signup and view all the answers

What is the primary mechanism by which air is drawn into the lungs?

<p>Difference in pleural pressures. (B)</p> Signup and view all the answers

If the alveolar pressure is zero and the atmospheric pressure is also zero, what will happen to airflow?

<p>There will be no airflow. (D)</p> Signup and view all the answers

Which statement correctly emphasizes the role of diaphragm contraction in breathing?

<p>It creates a more negative intrapleural pressure, allowing air to flow in. (B)</p> Signup and view all the answers

How does a hole in the lungs affect the pressures necessary for keeping the alveoli open?

<p>It changes the balance of pressures essential for expansion. (C)</p> Signup and view all the answers

During inhalation, what physiological change allows for increased air intake?

<p>An increase in lung volume. (D)</p> Signup and view all the answers

What is the total lung capacity composed of?

<p>Tidal volume, inspiratory reserve volume, and expiratory reserve volume (C)</p> Signup and view all the answers

Which of the following is true about the functional residual capacity?

<p>It is the volume left in the lungs after quiet expiration (A)</p> Signup and view all the answers

What characterizes the vital capacity in pulmonary physiology?

<p>It is the maximum air that can be exhaled (B)</p> Signup and view all the answers

What happens to the transpulmonary pressure if both alveolar pressure and intrapleural pressure are equal?

<p>Transpulmonary pressure is zero, leading to potential lung collapse (D)</p> Signup and view all the answers

Which pressure is considered most important for keeping the alveoli open?

<p>Transpulmonary pressure (B)</p> Signup and view all the answers

Which of the following correctly describes intrapleural pressure during normal quiet breathing?

<p>It is always negative (D)</p> Signup and view all the answers

What characterizes the inspiratory capacity?

<p>It is the maximum air that can be inhaled (D)</p> Signup and view all the answers

Why do lungs prefer to rest at functional residual capacity?

<p>Because it is a balanced equilibrium position of forces (C)</p> Signup and view all the answers

Which scenario is correct regarding pressures during the respiratory cycle?

<p>Transpulmonary pressure can be positive despite negative intrapleural pressure (C)</p> Signup and view all the answers

What does the term residual volume refer to?

<p>Air left in the lungs that can't be expelled (D)</p> Signup and view all the answers

Which lung capacity represents the total amount of air that can be held in the lungs?

<p>Total lung capacity (C)</p> Signup and view all the answers

During which part of the respiratory cycle is the intrapleural pressure at its highest?

<p>During forced exhalation (C)</p> Signup and view all the answers

What happens to the alveoli if transpulmonary pressure decreases below a critical level?

<p>They may collapse (B)</p> Signup and view all the answers

Which pressures are necessary to establish the transpulmonary pressure?

<p>Alveolar pressure minus intrapleural pressure (B)</p> Signup and view all the answers

The pressure volume curve for inhalation and ______ of the lungs do not look the same.

<p>exhalation</p> Signup and view all the answers

Surface tension in the lungs is a key factor that causes pressure volume ______.

<p>hysteresis</p> Signup and view all the answers

During inspiration, molecules in the lungs are ______ together, resulting in high surface tension.

<p>close</p> Signup and view all the answers

Expiration begins at ______ lung volumes, leading to a greater change in volume for a change in pressure.

<p>high</p> Signup and view all the answers

The difference in compliance between inhalation and exhalation is an important concept in pulmonary ______.

<p>physiology</p> Signup and view all the answers

The volume of air that moves in and out with quiet breathing is called the ______.

<p>tidal volume</p> Signup and view all the answers

When you exhale as forcefully as possible, the extra volume pushed out is known as the ______.

<p>expiratory reserve volume</p> Signup and view all the answers

The extra volume of air that can be inhaled beyond the tidal volume is referred to as the ______.

<p>inspiratory reserve volume</p> Signup and view all the answers

The amount of air that remains in the lungs after maximal exhalation is known as the ______.

<p>residual volume</p> Signup and view all the answers

The tidal volume is involved in which type of breathing, also known as ______ breathing?

<p>quiet</p> Signup and view all the answers

The residual volume is important because it represents the air that cannot be ______ out of the lungs.

<p>exhaled</p> Signup and view all the answers

During a maximal inhalation, the ______ is filled to its capacity.

<p>lung</p> Signup and view all the answers

The red line on the graph changes as a person inhales and exhales, indicating variations in ______.

<p>lung volume</p> Signup and view all the answers

The residual volume is the air that can't be blown out no matter how hard you try, and it is included in the total _____ capacity.

<p>lung</p> Signup and view all the answers

The inspiratory capacity includes tidal volume and the inspiratory _____ volume.

<p>reserve</p> Signup and view all the answers

The vital capacity is the most air that can be _____ after a deep inhalation.

<p>exhaled</p> Signup and view all the answers

Functional residual capacity includes residual volume plus the _____ reserve volume.

<p>expiratory</p> Signup and view all the answers

Atmospheric pressure is considered zero in pulmonary physiology for ease of _____ .

<p>calculations</p> Signup and view all the answers

Alveolar pressure is the pressure within the _____ as air is inhaled and exhaled.

<p>alveoli</p> Signup and view all the answers

Intrapleural pressure is the pressure found in the _____ space between the lungs and the chest wall.

<p>pleural</p> Signup and view all the answers

Transpulmonary pressure is the difference between alveolar pressure and _____ pressure.

<p>intrapleural</p> Signup and view all the answers

A negative intrapleural pressure acts like a vacuum, _____ the walls of the alveoli open.

<p>sucking</p> Signup and view all the answers

If the transpulmonary pressure is zero, the alveoli will likely _____ .

<p>collapse</p> Signup and view all the answers

During normal breathing, the intrapleural pressure is typically _____ at all times.

<p>negative</p> Signup and view all the answers

The lungs rest at the functional residual capacity, which is where the forces are _____ .

<p>balanced</p> Signup and view all the answers

During exhalation, the pressure in the alveoli ____ when air is expelled.

<p>increases</p> Signup and view all the answers

The chest wall wants to expand, creating a force that contributes to the _____ pressure in the pleural space.

<p>negative</p> Signup and view all the answers

The total lung capacity is about _____ liters in healthy adults.

<p>six</p> Signup and view all the answers

The pressure in the pleural space is always negative during ______ breathing.

<p>quiet</p> Signup and view all the answers

When there is no pressure inside the airways, the lungs have ______ volume.

<p>no</p> Signup and view all the answers

The tendency of the chest wall is to spring ______.

<p>outward</p> Signup and view all the answers

At a pressure of zero on the chest walls, they still have ______.

<p>volume</p> Signup and view all the answers

The volume of the lungs at the end of a quiet exhalation is known as the ______ residual capacity.

<p>functional</p> Signup and view all the answers

Lung compliance is defined as the change in ______ for a given change in pressure.

<p>volume</p> Signup and view all the answers

The relationship between pressure and volume is different when the lungs are ______ compared to being outside the body.

<p>inside</p> Signup and view all the answers

When the lungs are outside the body, they collapse completely due to ______ pressure.

<p>zero</p> Signup and view all the answers

During inspiration, the lungs expand and the pressure inside them becomes ______.

<p>negative</p> Signup and view all the answers

The collection of pressure-volume relationships for lungs, chest wall, and respiratory system is visualized in a ______.

<p>graph</p> Signup and view all the answers

During inhalation, the intrapleural pressure becomes more ______.

<p>negative</p> Signup and view all the answers

The green line represents the relationship of the ______ system as a whole.

<p>respiratory</p> Signup and view all the answers

The ______ pressure in the alveoli becomes negative during inhalation.

<p>alveolar</p> Signup and view all the answers

The state where the tendency of the lungs to collapse is balanced by the tendency of the chest wall to expand occurs at ______.

<p>FRC</p> Signup and view all the answers

Physiologists found a relationship between pressure applied to the lungs and changes in ______.

<p>volume</p> Signup and view all the answers

Physiologists originally studied lungs by applying pressure to them outside the body, using ______.

<p>cadavers</p> Signup and view all the answers

When the intrapleural pressure rises from -8 to -6.5, the alveolar pressure becomes ______.

<p>positive</p> Signup and view all the answers

Air always flows from areas of ______ pressure to areas of low pressure.

<p>high</p> Signup and view all the answers

At the end of inhalation, the alveolar pressure returns to ______.

<p>zero</p> Signup and view all the answers

During quiet breathing, we typically inhale about a half liter of ______.

<p>air</p> Signup and view all the answers

The change in intrapleural pressure during exhalation is from -6.5 to ______.

<p>-5</p> Signup and view all the answers

At functional residual capacity (FRC), the forces in the lungs are in ______.

<p>equilibrium</p> Signup and view all the answers

As air flows into the lungs, the overall lung ______ increases.

<p>volume</p> Signup and view all the answers

During exhalation, the lungs ______ due to the positive alveolar pressure.

<p>shrink</p> Signup and view all the answers

The pressure in the pleural space is typically always ______.

<p>negative</p> Signup and view all the answers

The ______ pressure is positive at +20.

<p>pleural</p> Signup and view all the answers

The diagram discussed reflects changes in ______ and pressure during tidal breathing.

<p>volume</p> Signup and view all the answers

The ______ pressure decreases during exhalation as air is expelled from the lungs.

<p>transpulmonary</p> Signup and view all the answers

The pressure inside the alveoli is even more positive at +______.

<p>35</p> Signup and view all the answers

The equal pressure point occurs when the pressure inside the lungs is equal to the ______ pressure.

<p>pleural</p> Signup and view all the answers

In healthy individuals, the equal pressure point occurs within the ______ airways.

<p>cartilaginous</p> Signup and view all the answers

In patients with disease lungs, the equal pressure point moves towards the ______.

<p>alveoli</p> Signup and view all the answers

In emphysema, there is a loss of elastic ______.

<p>recoil</p> Signup and view all the answers

The result of airway collapse can include obstruction to ______ and air trapping.

<p>airflow</p> Signup and view all the answers

Pursed lips create an ______ to airflow during exhalation.

<p>obstruction</p> Signup and view all the answers

The pressure drop in the bronchial airways occurs due to ______ of the walls.

<p>inflammation</p> Signup and view all the answers

Hysteresis refers to the dependence of a physical property on its ______.

<p>history</p> Signup and view all the answers

In patients with COPD, engagement in behaviors such as slow exhalation helps prevent ______ collapse.

<p>airway</p> Signup and view all the answers

During forced exhalation, the pleural pressure can rise significantly, leading to potential airway ______.

<p>collapse</p> Signup and view all the answers

The trachea and bronchi have ______ present to provide structural support.

<p>cartilage</p> Signup and view all the answers

Without cartilage, the bronchioles can ______ if pleural pressure exceeds airway pressure.

<p>collapse</p> Signup and view all the answers

In healthy patients, the pleural pressure does not lead to airway collapse because the equal pressure point occurs in the ______ airways.

<p>cartilaginous</p> Signup and view all the answers

Transpulmonary pressure is crucial for keeping the alveoli from collapsing, especially in cases of __________.

<p>pneumothorax</p> Signup and view all the answers

In a healthy lung, the pressure in the intrapleural space is typically __________.

<p>-5</p> Signup and view all the answers

When the pressure in the alveoli becomes positive, it causes air to flow __________ of the lungs.

<p>out</p> Signup and view all the answers

When the intrapleural pressure becomes more negative, the pressure in the alveoli becomes __________.

<p>negative</p> Signup and view all the answers

If the lungs are very compliant, it takes a small amount of diaphragm effort to generate just a small amount of pressure and you'll get a large volume change. So compliant lungs have an easy time moving air in and out because they easily expand and contract. Non-compliant lungs are ______.

<p>stiff</p> Signup and view all the answers

During exhalation, the diaphragm __________ and the intrapleural pressure becomes less negative.

<p>relaxes</p> Signup and view all the answers

Patients who have diseases where their lungs become non-compliant will have a lower ______.

<p>FRC</p> Signup and view all the answers

If the pressure in the alveoli is zero and the atmospheric pressure is also zero, there will be __________ in air flow.

<p>no change</p> Signup and view all the answers

The change in intrapleural pressure is the primary driver of __________ in the lungs.

<p>air flow</p> Signup and view all the answers

Increased lung compliance occurs in patients with ______.

<p>emphysema</p> Signup and view all the answers

Decreased lung compliance occurs in some disorders such as pneumonia and ______.

<p>pulmonary fibrosis</p> Signup and view all the answers

In a pneumothorax, the pressure in the intrapleural space becomes __________ due to a hole in the lungs.

<p>zero</p> Signup and view all the answers

During forced exhalation, the pleural pressure becomes ______.

<p>positive</p> Signup and view all the answers

The resting state in a quiet breathing cycle has a pressure of zero in the alveoli and __________ in the intrapleural space.

<p>-5</p> Signup and view all the answers

The pressure in the alveoli is governed by the dynamics of __________ pressure.

<p>transpulmonary</p> Signup and view all the answers

When making a forced exhalation, the pressure in the alveolus can be as high as ______.

<p>35</p> Signup and view all the answers

When the diaphragm contracts, the intrapleural pressure can become as negative as __________.

<p>-8</p> Signup and view all the answers

Older patients tend to have an increase in lung ______.

<p>compliance</p> Signup and view all the answers

The green line in the lung pressure-volume relationship graph represents the ______ as a whole.

<p>respiratory system</p> Signup and view all the answers

Air always flows from an area of __________ pressure to an area of lower pressure.

<p>higher</p> Signup and view all the answers

The primary function of surfactant is to reduce __________ in the alveoli.

<p>surface tension</p> Signup and view all the answers

When a lung becomes non-compliant, the pressure-volume curve will begin to resemble a ______ line.

<p>red</p> Signup and view all the answers

A higher compliance and FRC in patients often correlates with conditions like ______.

<p>barrel chest</p> Signup and view all the answers

The process of inhalation increases the pressure __________ inside the alveoli.

<p>gradient</p> Signup and view all the answers

Positive pressure in the alveoli during exhalation helps to __________ air out of the lungs.

<p>push</p> Signup and view all the answers

During forced exhalation, air flows out due to the developed pressure gradient, which results from the positive pressure in the ______.

<p>pleura</p> Signup and view all the answers

The equilibrium point where the chest wall is balanced with the lungs will be at a ______ value with non-compliant lungs.

<p>lower</p> Signup and view all the answers

Surfactant is important for maintaining lung ______.

<p>compliance</p> Signup and view all the answers

Elastic recoil of the lungs contributes to the significant pressure observed in the ______ during forced exhalation.

<p>alveolus</p> Signup and view all the answers

Flashcards

Tidal Volume

The volume of air inhaled and exhaled during normal, quiet breathing.

Expiratory Reserve Volume

The extra volume of air that can be exhaled forcefully after a normal exhalation.

Inspiratory Reserve Volume

The extra volume of air that can be inhaled forcefully after a normal inhalation.

Residual Volume

The volume of air remaining in the lungs after a maximum exhalation.

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Lung Volumes

The four measures of air in the lungs during breathing cycles.

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Quiet Breathing

Normal, automatic breathing without conscious effort.

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Forced Exhalation

Exhaling as hard as possible to push out the maximum amount of air.

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Forced Inhalation

Inhaling as hard as possible to fill the lungs to the maximum.

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Total Lung Capacity

The total amount of air your lungs can hold after a maximal inhalation.

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Inspiratory Capacity

The maximum amount of air you can inhale after a normal exhalation.

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Vital Capacity

The maximum amount of air you can exhale after a maximal inhalation.

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Functional Residual Capacity

The amount of air remaining in your lungs after a normal exhalation.

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Alveolar Pressure

The pressure inside the alveoli, the tiny air sacs where gas exchange occurs.

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Intrapleural Pressure

The pressure in the space between your lungs and chest wall.

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Transpulmonary Pressure

The difference between the alveolar pressure and the intrapleural pressure.

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Negative Intrapleural Pressure

The intrapleural pressure is always negative during normal breathing.

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Why is Transpulmonary Pressure Important?

A positive transpulmonary pressure is needed to keep alveoli open for gas exchange.

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Lung Collapse

What happens if transpulmonary pressure is too low.

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Lung Function

How lung volumes and pressures work together to ensure proper breathing.

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What does the chest wall want to do?

The chest wall wants to expand and move outwards.

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What do the lungs want to do?

The lungs want to recoil and collapse inwards naturally.

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How are lungs kept inflated?

Negative intrapleural pressure keeps the alveoli open.

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Equilibrium Position

The balance between the chest wall pulling out and the lungs pulling in.

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Pneumothorax

A condition where air leaks into the pleural space, causing the lung to collapse.

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What drives airflow?

Differences in pressure between the alveoli and the atmosphere.

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Flow out of the lungs

Occurs when the pressure inside the alveoli is higher than atmospheric pressure.

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Flow into the lungs

Occurs when the pressure inside the alveoli is lower than atmospheric pressure.

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Diaphragm Contraction

This action expands the chest cavity, makes the intrapleural pressure more negative, and draws air into the lungs.

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Diaphragm Relaxation

This action reduces the chest cavity volume, makes the intrapleural pressure less negative, and pushes air out of the lungs.

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Intrapleural Pressure During Inhalation

Becomes more negative, creating suction that draws air into the lungs.

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Intrapleural Pressure During Exhalation

Becomes less negative, reducing suction and pushing air out.

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Alveolar Pressure During Inhalation

Becomes negative, drawing air into the lungs.

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Alveolar Pressure During Exhalation

Becomes positive, pushing air out of the lungs.

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Key concept

Airflow in and out of the lungs is driven by changes in the intrapleural pressure.

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Resting State

The state where the lungs are relaxed and in equilibrium, with no airflow.

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Inhalation

The process of breathing in, where air flows into the lungs.

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Exhalation

The process of breathing out, where air flows out of the lungs.

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Airflow

The movement of air into or out of the lungs, driven by pressure differences.

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Lung Expansion

The increase in lung volume during inhalation, driven by transpulmonary pressure.

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Lung Shrinkage

The decrease in lung volume during exhalation, driven by transpulmonary pressure.

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FRC (Functional Residual Capacity)

The volume of air remaining in the lungs after a normal exhalation.

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Pressure and Volume Relationship

The relationship between pressure and volume in the lungs during breathing, where changes in one affect the other.

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Lung Pressure-Volume Relationship

The relationship between the pressure applied to the lungs and their resulting volume. This relationship differs when the lungs are inside the body compared to when they are outside.

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Chest Wall Pressure-Volume Relationship

The relationship between the pressure applied to the chest wall and its resulting volume. The chest wall naturally wants to expand outward.

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Lung Compliance

A measure of how easily the lungs can expand in response to a change in pressure.

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What determines lung volume at rest?

The balance between the chest wall's tendency to expand outward and the lungs' tendency to collapse inward determines the lung volume at rest.

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What happens to intrapleural pressure during inhalation?

Intrapleural pressure becomes even more negative, creating more suction that draws air into the lungs.

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What happens to intrapleural pressure during exhalation?

Intrapleural pressure becomes less negative, reducing the suction and allowing air to flow out.

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What determines airflow direction?

Airflow into or out of the lungs is determined by the pressure difference between the alveoli and the atmosphere.

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Why is negative intrapleural pressure crucial?

Negative intrapleural pressure keeps the alveoli open and prevents them from collapsing.

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What is the role of the diaphragm during inhalation?

The diaphragm contracts, expanding the chest cavity, making intrapleural pressure more negative and drawing air into the lungs.

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What is the role of the diaphragm during exhalation?

The diaphragm relaxes, reducing the chest cavity volume, making intrapleural pressure less negative and pushing air out of the lungs.

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What happens to alveolar pressure during inhalation?

Alveolar pressure becomes negative, drawing air into the lungs.

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What happens to alveolar pressure during exhalation?

Alveolar pressure becomes positive, pushing air out of the lungs.

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What is the key concept driving airflow in and out of the lungs?

Changes in intrapleural pressure, influenced by chest wall and diaphragm movements, drive the airflow into and out of the lungs.

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Effect of Compliance on Pressure-Volume Curve

Noncompliant lungs require more pressure to achieve the same volume change compared to compliant lungs. This is shown by a steeper pressure-volume curve.

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FRC and Lung Compliance

Decreased lung compliance lowers the FRC (Functional Residual Capacity), while increased compliance raises the FRC.

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Diseases Affecting Lung Compliance

Pneumonia, pulmonary edema, and fibrosis decrease compliance (stiffer lungs), while emphysema increases compliance (floppy lungs).

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FRC and Barrel Chest

Emphysema increases lung compliance, which raises the FRC. This leads to a barrel chest due to increased volume in the chest.

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Forced Exhalation - Pleural Pressure

During forced exhalation, the pleural pressure becomes positive, unlike the negative pressure in normal quiet breathing.

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Forced Exhalation - Alveolar Pressure

Alveolar pressure becomes higher than pleural pressure during forced exhalation due to the elastic recoil of the lungs.

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Forced Exhalation - Airflow

The large pressure gradient between the alveoli and the atmosphere (zero) drives the flow of air out of the lungs.

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Equal Pressure Point

The point in the airways during forced exhalation where the pressure in the airway equals the pressure in the surrounding alveoli.

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Why Don't Lungs Collapse During Forced Exhalation?

Even with positive pleural pressure during forced exhalation, the lungs don't collapse due to the equal pressure point where the pressure inside and outside the airways balances.

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Positive Pressure

Pressure higher than atmospheric pressure. Occurs in the pleural space during forced exhalation and in the alveoli during forced exhalation.

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Pressure Gradient

The difference in pressure between two areas. Drives airflow from high pressure to low pressure.

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Elastic Recoil of Lungs

The tendency of the lungs to collapse inwards due to their elasticity.

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Negative Pressure

Pressure lower than atmospheric pressure. Occurs in the pleural space during normal breathing.

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Pressure-Volume Hysteresis

The difference in pressure-volume curves during inhalation and exhalation, revealing different lung compliance during these phases.

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Surface Tension and Compliance

Surface tension, stronger at low lung volumes, resists expansion during inhalation, leading to lower compliance. Compliance increases during exhalation as intermolecular forces weaken.

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Inspiration Compliance

The ease of lung expansion during inhalation is reduced by strong intermolecular forces and surface tension at low lung volumes, leading to a steeper pressure-volume curve.

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Expiration Compliance

During exhalation, weakened intermolecular forces at high lung volumes allow for greater volume changes for a given pressure change, leading to a shallower pressure-volume curve.

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Hysteresis and Surface Tension

The difference in lung compliance during inspiration and expiration (hysteresis) is primarily caused by surface tension, which varies with lung volume.

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Why is the Equal Pressure Point Important?

It determines whether the airways will collapse or remain open during breathing. In healthy individuals, it occurs within the cartilaginous portion of the airways, preventing collapse.

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What happens if the Equal Pressure Point shifts?

If the equal pressure point moves towards the alveoli, the airways can collapse because they lack cartilage in the bronchioles and smaller airways.

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What causes the Equal Pressure Point to shift?

Conditions like bronchitis or emphysema can alter the airway pressure and cause the equal pressure point to move closer to the alveoli.

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How does Emphysema affect the Equal Pressure Point?

The loss of elastic recoil in emphysema weakens the airway walls, leading to a quicker pressure drop and a shift of the equal pressure point closer to the alveoli.

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How does Bronchitis affect the Equal Pressure Point?

Inflammation and swelling in the airways due to bronchitis obstruct airflow and increase pressure drop, causing the equal pressure point to shift closer to the alveoli.

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Why do COPD patients exhale slowly?

To minimize the pressure drop and prevent airway from collapsing. Exhaling slowly keeps the pleural pressure from rising significantly.

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Why do COPD patients purse their lips?

To increase airway pressure and prevent collapse. Pursing lips creates resistance to airflow, building pressure behind the obstruction.

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What is Hysteresis in this context?

The dependence of lung volume and pressure on their previous state. For example, air trapping due to airway collapse can affect the pressure changes during subsequent breaths.

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What is the key difference in lung function between healthy individuals and those with COPD?

Healthy individuals maintain a stable equal pressure point within the cartilaginous airways, preventing collapse. COPD patients have a shifted equal pressure point, leading to airway collapse during forceful exhalation.

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How does a healthy lung maintain its structure?

The cartilage in the bronchi and trachea provides structural support, preventing collapse even when pleural pressure is higher than airway pressure.

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Why can airway collapse be dangerous?

Airway collapse obstructs airflow, leading to air trapping and difficulty breathing. This can worsen lung function and contribute to respiratory distress.

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How do bronchioles differ from bronchus?

Bronchioles are smaller airways lacking cartilage, making them prone to collapse when the pleural pressure surpasses the airway pressure.

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What is the relationship between pleural pressure, airway pressure, and airway collapse?

When pleural pressure exceeds airway pressure, it can cause the airways to collapse, especially in regions lacking cartilage.

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What's the difference between Quiet Breathing and Forced Breathing?

Quiet breathing is the regular, automatic breathing we do without effort, while forced breathing involves consciously pushing out or pulling in more air.

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Functional Residual Capacity (FRC)

The volume of air remaining in the lungs after a normal exhalation. It's important for maintaining a stable lung volume.

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What is Intrapleural Pressure?

The pressure in the space between the lungs and the chest wall. This pressure is always negative during normal breathing.

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What does a positive Transpulmonary Pressure mean?

It indicates that the alveoli are open and able to exchange gases. If the pressure is too low, the alveoli collapse.

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Why is Intrapleural Pressure Negative?

The chest wall wants to expand, pulling outwards, while the lungs want to recoil inwards. The negative pressure pulls the lungs open.

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How does Intrapleural Pressure affect Lung Function?

Changes in intrapleural pressure drive the flow of air into and out of the lungs during breathing.

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What is the force that keeps the alveoli open?

The negative intrapleural pressure creates a positive transpulmonary pressure which keeps the alveoli expanded.

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What happens during inhalation?

The diaphragm contracts, expanding the chest cavity and making the intrapleural pressure more negative. This draws air into the lungs.

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What happens during exhalation?

The diaphragm relaxes, shrinking the chest cavity, making the intrapleural pressure less negative. This pushes air out of the lungs.

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What is the relationship between pressure and air flow?

Air flows from areas of high pressure to areas of low pressure. During inhalation, the alveolar pressure is lower than atmospheric pressure, causing air to flow in.

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Diaphragm contraction during inhalation

The diaphragm contracts, expanding the chest cavity, making the pressure between the lung and chest wall (intrapleural pressure) more negative, which draws air into the lungs.

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Diaphragm relaxation during exhalation

The diaphragm relaxes, reducing the chest cavity volume, making the pressure between the lung and chest wall (intrapleural pressure) less negative, which pushes air out of the lungs.

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Intrapleural pressure changes during breathing

The pressure between the lung and chest wall (intrapleural pressure) becomes more negative during inhalation and less negative during exhalation.

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Forced breathing

When we consciously push out or pull in extra air, using effort.

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How is Lung Volume at Rest Determined?

The balance between the chest wall wanting to expand outward and the lungs wanting to collapse inward determines the resting lung volume.

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What happens to intrapleural pressure during forced exhalation?

The intrapleural pressure becomes positive during forced exhalation, unlike the normal negative pressure.

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What causes Hysteresis?

Hysteresis in the lungs is mainly due to surface tension. Surface tension is stronger at low lung volumes, making it harder to expand the lungs during inhalation. During exhalation, the surface tension is weaker because the lung volume is larger. This leads to different pressure-volume relationships in inspiration and expiration.

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How does Hysteresis impact breathing?

The different levels of compliance during inspiration and expiration affect how efficiently the lungs can draw in air and expel it. It explains why the pressure-volume relationships differ between inhalation and exhalation.

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Cartilaginous Airways

Parts of the airway that have cartilage, providing structural support to prevent collapse.

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Why Does Airway Collapse Happen?

Airway collapse occurs when the pleural pressure becomes higher than the inside pressure in the airway, causing the airway to collapse inwards.

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Where Should the Equal Pressure Point Be?

In healthy lungs, the equal pressure point should be located within the cartilaginous airways, preventing airway collapse.

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What Happens in Emphysema?

Emphysema damages the lungs, causing them to lose elastic recoil. This leads to a faster pressure drop and shifts the equal pressure point towards the alveoli, increasing the risk of airway collapse.

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How Does Bronchitis Affect Airway Collapse?

Bronchitis causes inflammation and swelling of the airways, obstructing airflow and increasing pressure drop, causing the equal pressure point to shift towards the alveoli and increasing the risk of airway collapse.

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What is Hysteresis in Respiration?

Hysteresis in respiration refers to how the volume and pressure of the lungs depend on their previous state. It means that the lungs might not behave the same way during inhalation and exhalation.

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Why is Airway Collapse Dangerous?

Airway collapse obstructs airflow, leading to air trapping and difficulty breathing, potentially worsening lung function and resulting in respiratory distress.

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What is the Difference Between Quiet and Forced Breathing?

Quiet breathing is the normal, automatic breathing we do without effort, while forced breathing involves consciously using more effort to push out or pull in air.

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What is Functional Residual Capacity (FRC)?

The volume of air remaining in the lungs after a normal exhalation, important for maintaining a stable lung volume and preventing collapse.

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What is the Equal Pressure Point?

The point in the airways during forced exhalation where the pressure in the airway equals the pressure in the surrounding alveoli.

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Equal Pressure Point Shift: Collapse

If the equal pressure point shifts towards the alveoli, the airways can collapse because they lack cartilage in the bronchioles and smaller airways.

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COPD and Exhalation

COPD patients exhale slowly to minimize pressure drop and prevent airway collapse. They also purse their lips to create resistance and increase airway pressure.

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Hysteresis: Lung Volume and Pressure

The dependence of lung volume and pressure on their previous state. For example, air trapping due to airway collapse can affect the pressure changes during subsequent breaths.

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Healthy vs. COPD: Lung Function

Healthy individuals maintain a stable equal pressure point within the cartilaginous airways, preventing collapse. COPD patients have a shifted equal pressure point, leading to airway collapse during forced exhalation.

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Airway Collapse: Consequences

Airway collapse obstructs airflow, leading to air trapping and difficulty breathing. It can worsen lung function and contribute to respiratory distress.

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Study Notes

Lung Volumes and Capacities

  • Tidal Volume (TV): The volume of air inhaled and exhaled during quiet breathing.
  • Expiratory Reserve Volume (ERV): The extra volume of air that can be forcefully exhaled after a normal exhalation.
  • Inspiratory Reserve Volume (IRV): The extra volume of air that can be forcefully inhaled after a normal inhalation.
  • Residual Volume (RV): The volume of air remaining in the lungs after a maximal exhalation; cannot be expelled.

Lung Capacities

  • Total Lung Capacity (TLC): The sum of all lung volumes (TV + ERV + IRV + RV).
  • Inspiratory Capacity (IC): The maximum volume of air that can be inhaled from the end of a normal exhalation (IRV + TV).
  • Vital Capacity (VC): The maximum volume of air that can be exhaled from the end of a maximal inhalation (ERV + TV + IRV).
  • Functional Residual Capacity (FRC): The volume of air remaining in the lungs after a normal exhalation (RV + ERV). This is the equilibrium point where lung and chest wall forces are balanced.

Lung Pressures

  • Atmospheric Pressure: 760 mmHg (often considered zero in pulmonary physiology).
  • Alveolar Pressure: The pressure within the alveoli.
  • Intrapleural Pressure: The pressure within the pleural space (always negative).
  • Transpulmonary Pressure (TPP): The difference between alveolar pressure and intrapleural pressure. A positive TPP keeps alveoli open.

Respiratory Cycle

  • Inhalation: The diaphragm contracts, increasing the volume of the thoracic cavity, decreasing intrapleural pressure (more negative), which decreases alveolar pressure allowing air to flow into the lungs.
  • Exhalation: The diaphragm relaxes, decreasing the volume of the thoracic cavity, increasing intrapleural pressure (less negative), which increases alveolar pressure forcing air out of the lungs.

Pneumothorax

  • A pneumothorax is a hole in the lung.
  • This allows atmospheric pressure to enter the pleural space, eliminating the negative intrapleural pressure.
  • The transpulmonary pressure is reduced to zero, causing lung collapse, as there is no longer enough pressure and force to keep alveoli open.

Forced Exhalation

  • Equal Pressure Point: During forced exhalation, pleural pressure becomes positive. The equal pressure point is where the pressure within the airway equals the pleural pressure.
  • Beyond this point, collapse of small airways can occur if the pleural pressure exceeds airway pressure.
  • In healthy individuals, this point occurs in the cartilaginous airways preventing collapse; but can be compromised in COPD patients, where the equal pressure point occurs in non-cartilaginous airways resulting in airway collapse and obstruction.

Lung Compliance

  • Compliance: A measure of how easily the lungs expand (change in volume / change in pressure).
  • Noncompliant lungs (stiff): Require greater pressure changes to achieve a given volume change, making breathing difficult.
  • Highly compliant lungs (floppy): Expand easily with small pressure changes, making breathing easier.
  • FRC and Compliance: A change in lung compliance affects the functional residual capacity (FRC). Decreased compliance leads to a lower FRC; increased compliance leads to a higher FRC.

Hysteresis

  • Hysteresis: The difference between the pressure-volume curve of inhalation vs exhalation.
  • Surface Tension: Differences in the pressure volume curve for inhalation and exhalation are due to surface tension in the alveoli. Inhalation requires greater pressure for less volume change due to higher intermolecular forces. Exhalation has a gentler slope with larger volume change at lesser pressure due to decreased intermolecular forces.

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Test your knowledge on lung volumes and capacities in this comprehensive quiz. Learn about various respiratory metrics such as Tidal Volume, Residual Volume, and more. Ideal for students studying human anatomy and physiology.

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