Podcast
Questions and Answers
The respiratory system's efficiency in delivering oxygen and carbon dioxide depends solely on the volume of the lungs.
The respiratory system's efficiency in delivering oxygen and carbon dioxide depends solely on the volume of the lungs.
False (B)
The rate of respiration remains constant at 12-16 breaths per minute, regardless of conscious effort.
The rate of respiration remains constant at 12-16 breaths per minute, regardless of conscious effort.
False (B)
The respiratory cycle consists of inspiration, expiration, and a consistent pause.
The respiratory cycle consists of inspiration, expiration, and a consistent pause.
False (B)
Lung volumes refer to the combination of two or more lung capacities making up the total lung volume.
Lung volumes refer to the combination of two or more lung capacities making up the total lung volume.
Tidal Volume (TV) represents the amount of air inspired or expired during a forced, deep breath.
Tidal Volume (TV) represents the amount of air inspired or expired during a forced, deep breath.
The average Tidal Volume is approximately 750 ml in both males and females.
The average Tidal Volume is approximately 750 ml in both males and females.
Inspiratory Reserve Volume (IRV) is the amount of air that can be forcibly inspired in addition to a normal inspiration.
Inspiratory Reserve Volume (IRV) is the amount of air that can be forcibly inspired in addition to a normal inspiration.
Expiratory Reserve Volume (ERV) is the maximum amount of air remaining in the lungs after a maximal exhalation.
Expiratory Reserve Volume (ERV) is the maximum amount of air remaining in the lungs after a maximal exhalation.
Residual Volume (RV) is the amount of air that remains trapped in the lungs even after maximal exhalation.
Residual Volume (RV) is the amount of air that remains trapped in the lungs even after maximal exhalation.
Lacking surfactant, alveoli tend to fully empty during exhalation, decreasing the lungs residual volume.
Lacking surfactant, alveoli tend to fully empty during exhalation, decreasing the lungs residual volume.
Vital Capacity (VC) describes the minimal volume of air a person can expel from the lungs, reached after a quiet expiration.
Vital Capacity (VC) describes the minimal volume of air a person can expel from the lungs, reached after a quiet expiration.
Inspiratory Capacity (IC) is the amount of air a person can breathe in with maximum effort, starting from the end of a normal inhalation.
Inspiratory Capacity (IC) is the amount of air a person can breathe in with maximum effort, starting from the end of a normal inhalation.
Total Lung Capacity (TLC) represents the volume of air present in the lungs after maximal exhalation.
Total Lung Capacity (TLC) represents the volume of air present in the lungs after maximal exhalation.
The values for respiratory volumes and capacities are consistent across all individuals, regardless of sex, size, or age.
The values for respiratory volumes and capacities are consistent across all individuals, regardless of sex, size, or age.
Minute Ventilation is calculated by multiplying the tidal volume by the rate of respiration.
Minute Ventilation is calculated by multiplying the tidal volume by the rate of respiration.
Alveolar ventilation accounts for the air remaining in the upper respiratory passages, which exchanges gases.
Alveolar ventilation accounts for the air remaining in the upper respiratory passages, which exchanges gases.
Maximum Voluntary Ventilation (MVV) measures the amount of air that can be moved into or out of the lungs with minimal effort over a prolonged period.
Maximum Voluntary Ventilation (MVV) measures the amount of air that can be moved into or out of the lungs with minimal effort over a prolonged period.
Measurements of respiratory volumes and capacities can completely determine the ability to move air in and out of the lungs.
Measurements of respiratory volumes and capacities can completely determine the ability to move air in and out of the lungs.
In restrictive pulmonary diseases, lung volumes and capacities are generally normal.
In restrictive pulmonary diseases, lung volumes and capacities are generally normal.
Silicosis results in increased dispensability and decreased stiffness of the lungs.
Silicosis results in increased dispensability and decreased stiffness of the lungs.
In obstructive pulmonary diseases, excess mucous secretion generally widens airways, facilitating easier breathing.
In obstructive pulmonary diseases, excess mucous secretion generally widens airways, facilitating easier breathing.
In asthma, respiratory volumes are always significantly reduced.
In asthma, respiratory volumes are always significantly reduced.
The subject should avoid practicing breathing through the spirometer mouthpiece before measurement.
The subject should avoid practicing breathing through the spirometer mouthpiece before measurement.
When measuring expiratory reserve volume the subject should inhale then exhale maximally into the device three times, recording the smallest volume in the table.
When measuring expiratory reserve volume the subject should inhale then exhale maximally into the device three times, recording the smallest volume in the table.
When utilizing a handheld spirometer the device can be used for both inhalation and exhalation.
When utilizing a handheld spirometer the device can be used for both inhalation and exhalation.
The normal value for Tidal Volume is approximately 500 mL.
The normal value for Tidal Volume is approximately 500 mL.
A person can typically inhale more air than they can exhale.
A person can typically inhale more air than they can exhale.
The normal value for Expiratory Reserve Volume (ERV) is approximately 1200 mL.
The normal value for Expiratory Reserve Volume (ERV) is approximately 1200 mL.
The normal value for Vital Capacity is approximately 4700 mL.
The normal value for Vital Capacity is approximately 4700 mL.
The Inspiratory Reserve Volume (IRV) can be calculated using the formula: VC + ERV - TV.
The Inspiratory Reserve Volume (IRV) can be calculated using the formula: VC + ERV - TV.
An increased rate of alveolar ventilation results in a lower concentration of carbon dioxide in the body.
An increased rate of alveolar ventilation results in a lower concentration of carbon dioxide in the body.
The formula to determine the Functional Residual Capacity (FRC) is: ERV + RV. This result when calculated should be around 2500 ml.
The formula to determine the Functional Residual Capacity (FRC) is: ERV + RV. This result when calculated should be around 2500 ml.
If a patient has an obstructive pulmonary disease, their vital capacity is always higher than healthy individuals, due to them taking larger breaths.
If a patient has an obstructive pulmonary disease, their vital capacity is always higher than healthy individuals, due to them taking larger breaths.
The primary goal of measuring respiratory function is to quantify lung diseases and is of no help when determining drug dosage.
The primary goal of measuring respiratory function is to quantify lung diseases and is of no help when determining drug dosage.
The volume of anatomical dead space remains fixed relative to the respiratory rate during activities like exercise or singing.
The volume of anatomical dead space remains fixed relative to the respiratory rate during activities like exercise or singing.
Airway secretions have no impact on lung volumetric measures.
Airway secretions have no impact on lung volumetric measures.
An increase in Tidal Volume will always be matched by a corresponding reduction in respiratory rate to maintain stable blood pH.
An increase in Tidal Volume will always be matched by a corresponding reduction in respiratory rate to maintain stable blood pH.
Variations in the respiratory rate, depth, and rhythm are solely attributed to conscious breathing efforts.
Variations in the respiratory rate, depth, and rhythm are solely attributed to conscious breathing efforts.
Increasing lung capillary perfusion decreases alveolar ventilation, since less time is available for carbon dioxide and oxygen transfer.
Increasing lung capillary perfusion decreases alveolar ventilation, since less time is available for carbon dioxide and oxygen transfer.
Respiratory rate is inversely related to the duration of the pause between breaths.
Respiratory rate is inversely related to the duration of the pause between breaths.
Individuals with reduced lung size typically have Inspiratory Reserve Volumes closest to 3000 ml.
Individuals with reduced lung size typically have Inspiratory Reserve Volumes closest to 3000 ml.
Flashcards
Respiratory Rate
Respiratory Rate
The number of breaths per minute, typically 12-16 at rest, but varies.
Respiratory Cycle
Respiratory Cycle
Inspiration, expiration, and a pause that varies inversely with rate.
Tidal Volume (TV)
Tidal Volume (TV)
Air volume inspired or expired during a single, quiet breath (500 ml).
Inspiratory Reserve Volume (IRV)
Inspiratory Reserve Volume (IRV)
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Expiratory Reserve Volume (ERV)
Expiratory Reserve Volume (ERV)
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Residual Volume (RV)
Residual Volume (RV)
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Vital Capacity (VC)
Vital Capacity (VC)
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Inspiratory Capacity (IC)
Inspiratory Capacity (IC)
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Functional Residual Capacity (FRC)
Functional Residual Capacity (FRC)
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Total Lung Capacity (TLC)
Total Lung Capacity (TLC)
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Minute Ventilation (MV)
Minute Ventilation (MV)
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Alveolar Ventilation
Alveolar Ventilation
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Max Voluntary Ventilation (MVV)
Max Voluntary Ventilation (MVV)
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Tachypnea
Tachypnea
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Bradypnea
Bradypnea
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Hyperpnea
Hyperpnea
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Hyperventilation
Hyperventilation
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Hypoventilation
Hypoventilation
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Apnea
Apnea
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Dyspnea
Dyspnea
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Hypoxia
Hypoxia
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Hypercapnia
Hypercapnia
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Hypocapnia
Hypocapnia
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Study Notes
- Respiratory system's ability to deliver O2 and CO2 depends both on lung volume and the ability to move air quickly.
Definitions and Terminology
- Rate of respiration varies, even at rest (12–16/min); can be consciously altered.
- Respiratory cycle includes inspiration, expiration, and a pause.
- Pause duration varies inversely with rate.
Lung Volumes and Capacities
- Lung volumes are non-overlapping subdivisions of total lung air.
- Lung capacities are combinations of two or more lung volumes.
- Tidal Volume (TV): Air volume inspired/expired during quiet breath (500 ml in both sexes).
- Inspiratory Reserve Volume (IRV): Air volume forcibly inspired above normal (3,300 ml male, 1,900 ml female).
- Expiratory Reserve Volume (ERV): Air volume forcibly exhaled after normal (1,000 ml male, 700 ml female).
- Reserve volumes (IRV & ERV) allow for additional air intake/expulsion beyond normal breathing.
- Residual Volume (RV): Air remaining in lungs after maximal exhalation (1,200 ml male, 1,100 ml female).
- Surfactant prevents alveolar collapse, maintaining resident air volume.
Lung Capacities
- Vital Capacity (VC)/Forced Vital Capacity (FVC)/Forced Expiratory Volume (FEV): Maximum air volume expelled after deepest inspiration (3.5-5.5 liters).
- Inspiratory Capacity (IC): Maximum air volume inhaled with effort from end-expiratory point (~3000 ml).
- Functional Residual Capacity (FRC): Air remaining in lungs after normal expiration (~2500 ml).
- Total Lung Capacity (TLC): Air volume in lungs after deepest inspiration (4500–6000 ml)
Volumes and Capacities
- Normal adult values exist, with female values 20-25% smaller, influenced by size, age, and condition.
- Minute Ventilation (MV): Air breathed in/out per minute at rest (6–8 liters/min).
- Alveolar Ventilation: 350 ml of 500 ml tidal volume reaches respiratory zone for gas exchange (4.2-5.6 liters/min).
- Maximum Voluntary Ventilation (MVV): Air moved in/out with maximum effort in one minute (100–140 liters/min).
Clinical Significance
- Measured in clinical assessment of pulmonary disorders, which are classified into obstructive and restrictive.
- Obstructive disorders (e.g., emphysema, asthma) cause airflow reduction via airway blockage.
- The result of obstructive disorders is increased airway resistance, making breathing difficult.
- Asthma may prolong inspiration/expiration, but respiratory volumes may appear normal.
- Measurements of respiratory volumes say nothing about the ability to move air in and out of the lungs which is critical for O2 delivery.
- Restrictive disorders (e.g., pulmonary fibrosis) reduce lung capacities and volumes.
- In silicosis (grinder's disease), lungs lose dispensability and stiffen.
- Measurements of respiratory volumes/capacities help diagnose restrictive diseases.
Spirometry Experimental Procedures
- Practice breathing through spirometer mouthpiece with nose pinched can help to normalize breathing before measuring.
- Measuring Expiratory Reserve Volume: The subject stands, breathes normally for about a minute.
- After a normal exhalation, the subject forcibly exhales as much as possible.
- Repeat the measurement 3 times and record the largest volume.
- Measuring Vital Capacity: The subject stands, breathes normally for about a minute.
- Then inhales as deeply as possible and exhales with maximal effort.
- Repeat the measurement three times and record the largest volume.
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