Lung Volumes and Capacities

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Questions and Answers

The respiratory system's efficiency in delivering oxygen and carbon dioxide depends solely on the volume of the lungs.

False (B)

The rate of respiration remains constant at 12-16 breaths per minute, regardless of conscious effort.

False (B)

The respiratory cycle consists of inspiration, expiration, and a consistent pause.

False (B)

Lung volumes refer to the combination of two or more lung capacities making up the total lung volume.

<p>False (B)</p>
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Tidal Volume (TV) represents the amount of air inspired or expired during a forced, deep breath.

<p>False (B)</p>
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The average Tidal Volume is approximately 750 ml in both males and females.

<p>False (B)</p>
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Inspiratory Reserve Volume (IRV) is the amount of air that can be forcibly inspired in addition to a normal inspiration.

<p>True (A)</p>
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Expiratory Reserve Volume (ERV) is the maximum amount of air remaining in the lungs after a maximal exhalation.

<p>False (B)</p>
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Residual Volume (RV) is the amount of air that remains trapped in the lungs even after maximal exhalation.

<p>True (A)</p>
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Lacking surfactant, alveoli tend to fully empty during exhalation, decreasing the lungs residual volume.

<p>False (B)</p>
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Vital Capacity (VC) describes the minimal volume of air a person can expel from the lungs, reached after a quiet expiration.

<p>False (B)</p>
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Inspiratory Capacity (IC) is the amount of air a person can breathe in with maximum effort, starting from the end of a normal inhalation.

<p>False (B)</p>
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Total Lung Capacity (TLC) represents the volume of air present in the lungs after maximal exhalation.

<p>False (B)</p>
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The values for respiratory volumes and capacities are consistent across all individuals, regardless of sex, size, or age.

<p>False (B)</p>
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Minute Ventilation is calculated by multiplying the tidal volume by the rate of respiration.

<p>True (A)</p>
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Alveolar ventilation accounts for the air remaining in the upper respiratory passages, which exchanges gases.

<p>False (B)</p>
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Maximum Voluntary Ventilation (MVV) measures the amount of air that can be moved into or out of the lungs with minimal effort over a prolonged period.

<p>False (B)</p>
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Measurements of respiratory volumes and capacities can completely determine the ability to move air in and out of the lungs.

<p>False (B)</p>
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In restrictive pulmonary diseases, lung volumes and capacities are generally normal.

<p>False (B)</p>
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Silicosis results in increased dispensability and decreased stiffness of the lungs.

<p>False (B)</p>
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In obstructive pulmonary diseases, excess mucous secretion generally widens airways, facilitating easier breathing.

<p>False (B)</p>
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In asthma, respiratory volumes are always significantly reduced.

<p>False (B)</p>
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The subject should avoid practicing breathing through the spirometer mouthpiece before measurement.

<p>False (B)</p>
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When measuring expiratory reserve volume the subject should inhale then exhale maximally into the device three times, recording the smallest volume in the table.

<p>False (B)</p>
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When utilizing a handheld spirometer the device can be used for both inhalation and exhalation.

<p>False (B)</p>
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The normal value for Tidal Volume is approximately 500 mL.

<p>True (A)</p>
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A person can typically inhale more air than they can exhale.

<p>False (B)</p>
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The normal value for Expiratory Reserve Volume (ERV) is approximately 1200 mL.

<p>True (A)</p>
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The normal value for Vital Capacity is approximately 4700 mL.

<p>True (A)</p>
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The Inspiratory Reserve Volume (IRV) can be calculated using the formula: VC + ERV - TV.

<p>False (B)</p>
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An increased rate of alveolar ventilation results in a lower concentration of carbon dioxide in the body.

<p>True (A)</p>
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The formula to determine the Functional Residual Capacity (FRC) is: ERV + RV. This result when calculated should be around 2500 ml.

<p>False (B)</p>
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If a patient has an obstructive pulmonary disease, their vital capacity is always higher than healthy individuals, due to them taking larger breaths.

<p>False (B)</p>
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The primary goal of measuring respiratory function is to quantify lung diseases and is of no help when determining drug dosage.

<p>False (B)</p>
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The volume of anatomical dead space remains fixed relative to the respiratory rate during activities like exercise or singing.

<p>False (B)</p>
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Airway secretions have no impact on lung volumetric measures.

<p>False (B)</p>
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An increase in Tidal Volume will always be matched by a corresponding reduction in respiratory rate to maintain stable blood pH.

<p>False (B)</p>
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Variations in the respiratory rate, depth, and rhythm are solely attributed to conscious breathing efforts.

<p>False (B)</p>
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Increasing lung capillary perfusion decreases alveolar ventilation, since less time is available for carbon dioxide and oxygen transfer.

<p>False (B)</p>
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Respiratory rate is inversely related to the duration of the pause between breaths.

<p>True (A)</p>
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Individuals with reduced lung size typically have Inspiratory Reserve Volumes closest to 3000 ml.

<p>False (B)</p>
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Flashcards

Respiratory Rate

The number of breaths per minute, typically 12-16 at rest, but varies.

Respiratory Cycle

Inspiration, expiration, and a pause that varies inversely with rate.

Tidal Volume (TV)

Air volume inspired or expired during a single, quiet breath (500 ml).

Inspiratory Reserve Volume (IRV)

Air volume forcibly inspired above a normal inspiration (3,300 ml in males, 1,900 ml in females).

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Expiratory Reserve Volume (ERV)

Air volume forcibly exhaled after a normal exhalation (1,000 ml in males, 700 ml in females).

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Residual Volume (RV)

Air volume remaining in lungs after maximal exhalation. (1,200 ml in males, 1,100 ml in females).

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Vital Capacity (VC)

Largest air volume expelled after maximum inspiration (3.5 to 5.5 liters).

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Inspiratory Capacity (IC)

Maximum air volume inhaled with maximum effort, starting at the end of normal expiration (about 3000 ml).

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Functional Residual Capacity (FRC)

Air remaining in lungs at the end of normal expiration (about 2500 ml).

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Total Lung Capacity (TLC)

Total air volume in the lungs after deepest possible inspiration (4500–6000 ml).

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Minute Ventilation (MV)

Air breathed in/out per minute at rest (6-8 liters/min).

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Alveolar Ventilation

Air reaching respiratory zone (350 ml/breath).

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Max Voluntary Ventilation (MVV)

Air moved in/out of lungs with max effort in one minute (100-140 liters/min).

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Tachypnea

Breathing is faster than normal.

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Bradypnea

Slower than normal breathing.

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Hyperpnea

Increased depth and rate of breathing.

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Hyperventilation

Increased rate and depth of breathing to reduce arterial CO2

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Hypoventilation

Decreased depth and rate of breathing

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Apnea

Temporary cessation of breathing.

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Dyspnea

Difficult or labored breathing.

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Hypoxia

Deficiency in the amount of oxygen reaching the tissues.

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Hypercapnia

Excessive carbon dioxide in the bloodstream.

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Hypocapnia

Deficiency of carbon dioxide in the bloodstream.

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Study Notes

  • Respiratory system's ability to deliver O2 and CO2 depends both on lung volume and the ability to move air quickly.

Definitions and Terminology

  • Rate of respiration varies, even at rest (12–16/min); can be consciously altered.
  • Respiratory cycle includes inspiration, expiration, and a pause.
  • Pause duration varies inversely with rate.

Lung Volumes and Capacities

  • Lung volumes are non-overlapping subdivisions of total lung air.
  • Lung capacities are combinations of two or more lung volumes.
  • Tidal Volume (TV): Air volume inspired/expired during quiet breath (500 ml in both sexes).
  • Inspiratory Reserve Volume (IRV): Air volume forcibly inspired above normal (3,300 ml male, 1,900 ml female).
  • Expiratory Reserve Volume (ERV): Air volume forcibly exhaled after normal (1,000 ml male, 700 ml female).
  • Reserve volumes (IRV & ERV) allow for additional air intake/expulsion beyond normal breathing.
  • Residual Volume (RV): Air remaining in lungs after maximal exhalation (1,200 ml male, 1,100 ml female).
  • Surfactant prevents alveolar collapse, maintaining resident air volume.

Lung Capacities

  • Vital Capacity (VC)/Forced Vital Capacity (FVC)/Forced Expiratory Volume (FEV): Maximum air volume expelled after deepest inspiration (3.5-5.5 liters).
  • Inspiratory Capacity (IC): Maximum air volume inhaled with effort from end-expiratory point (~3000 ml).
  • Functional Residual Capacity (FRC): Air remaining in lungs after normal expiration (~2500 ml).
  • Total Lung Capacity (TLC): Air volume in lungs after deepest inspiration (4500–6000 ml)

Volumes and Capacities

  • Normal adult values exist, with female values 20-25% smaller, influenced by size, age, and condition.
  • Minute Ventilation (MV): Air breathed in/out per minute at rest (6–8 liters/min).
  • Alveolar Ventilation: 350 ml of 500 ml tidal volume reaches respiratory zone for gas exchange (4.2-5.6 liters/min).
  • Maximum Voluntary Ventilation (MVV): Air moved in/out with maximum effort in one minute (100–140 liters/min).

Clinical Significance

  • Measured in clinical assessment of pulmonary disorders, which are classified into obstructive and restrictive.
  • Obstructive disorders (e.g., emphysema, asthma) cause airflow reduction via airway blockage.
  • The result of obstructive disorders is increased airway resistance, making breathing difficult.
  • Asthma may prolong inspiration/expiration, but respiratory volumes may appear normal.
  • Measurements of respiratory volumes say nothing about the ability to move air in and out of the lungs which is critical for O2 delivery.
  • Restrictive disorders (e.g., pulmonary fibrosis) reduce lung capacities and volumes.
  • In silicosis (grinder's disease), lungs lose dispensability and stiffen.
  • Measurements of respiratory volumes/capacities help diagnose restrictive diseases.

Spirometry Experimental Procedures

  • Practice breathing through spirometer mouthpiece with nose pinched can help to normalize breathing before measuring.
  • Measuring Expiratory Reserve Volume: The subject stands, breathes normally for about a minute.
  • After a normal exhalation, the subject forcibly exhales as much as possible.
  • Repeat the measurement 3 times and record the largest volume.
  • Measuring Vital Capacity: The subject stands, breathes normally for about a minute.
  • Then inhales as deeply as possible and exhales with maximal effort.
  • Repeat the measurement three times and record the largest volume.

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