Lung Disease Patient Identification
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Questions and Answers

What percentage of lung nodules are benign?

  • 95% (correct)
  • 35%
  • 62%
  • 65%

    • What stage are most malignant nodules?

  • Stage I (correct)
  • Stage III
  • Stage II
  • Stage IV

    • What percentage of biopsies are on benign nodules?

  • 70%
  • 62% (correct)
  • 35%
  • 50%

    • What percentage of surgeries are on benign nodules?

    <p>35%</p> Signup and view all the answers

    What percentage of patients sent to CT surveillance have lung cancer?

    <p>17%</p> Signup and view all the answers

    How long does NODIFY LUNG TESTING take to produce results?

    <p>One day</p> Signup and view all the answers

    What is the name of the guidelines used for new 8 to 30 mm pulmonary nodules?

    <p>ACCP Guidelines</p> Signup and view all the answers

    What is the purpose of NODIFY LUNG TESTING?

    <p>To reclassify risk of malignancy</p> Signup and view all the answers

    What percentage of patients moved into the very low-risk group?

    <p>65%</p> Signup and view all the answers

    Which category identifies patients who may benefit from CT surveillance?

    <p>Very Low Risk</p> Signup and view all the answers

    What percentage of patients are in the High Risk category?

    <p>35%</p> Signup and view all the answers

    How many weeks does it take to get the results?

    <p>1 week</p> Signup and view all the answers

    What percentage of patients are Low to Moderate Risk?

    <p>35%</p> Signup and view all the answers

    What is the percentage of patients who are less likely to undergo unnecessary procedures according to the Nodify XL2 test?

    <p>74%</p> Signup and view all the answers

    What is the importance of nodule size in predicting the risk of malignancy?

    <p>It is as important as plasma protein levels</p> Signup and view all the answers

    What is the performance of the Likely Benign result reflected by?

    <p>30% negative predictive value</p> Signup and view all the answers

    What is the cost of Nodify lung testing for Medicare beneficiaries?

    <p>It is $0 out of pocket</p> Signup and view all the answers

    What is the percentage of nodules that are likely to be benign according to the Nodify XL2 test?

    <p>97%</p> Signup and view all the answers

    What is the risk of malignancy for this patient after the Nodify XL2 test?

    <p>3%</p> Signup and view all the answers

    What is the clinical risk factor associated with a 7.3% decrease in invasive procedures?

    <p>Location</p> Signup and view all the answers

    What is the purpose of the Nodify XL2 test?

    <p>To reduce invasive procedures on benign nodules</p> Signup and view all the answers

    What percentage of reported results indicate a high level of autoantibodies detected?

    <p>5%</p> Signup and view all the answers

    What is the recommended action for patients with a solitary pulmonary nodule (SPN) of 8-30 mm?

    <p>Nodify CDT testing</p> Signup and view all the answers

    Which of the following is NOT a condition for Nodify XL2 testing eligibility?

    <p>Patient has a biopsy-proven lung cancer</p> Signup and view all the answers

    What is the recommended method for coordinating the blood draw for Nodify CDT testing?

    <p>All of the above</p> Signup and view all the answers

    How long does it take to receive Nodify CDT results if the test is positive?

    <p>1 day</p> Signup and view all the answers

    What percentage of reported results indicate a moderate level of autoantibodies detected?

    <p>10%</p> Signup and view all the answers

    How can the Solitary Pulmonary Nodule Calculator be accessed?

    <p>On the Biodesix website</p> Signup and view all the answers

    What is the recommended course of action for patients at high risk of malignancy?

    <p>Timely intervention</p> Signup and view all the answers

    How are patients informed about the Nodify testing process?

    <p>During an in-office consultation</p> Signup and view all the answers

    What is the purpose of the Test Request Form (TRF)?

    <p>To coordinate the blood draw</p> Signup and view all the answers

    What is the primary purpose of the Nodify CDT test?

    <p>To identify patients with likely malignant lung nodules</p> Signup and view all the answers

    What type of antigens are measured by the Nodify CDT test?

    <p>Tumor-associated antigens</p> Signup and view all the answers

    What is the significance of a High Level result in the Nodify CDT test?

    <p>It indicates a high risk of malignancy</p> Signup and view all the answers

    What is the clinical risk factor associated with the patient's 4 mm solid nodule?

    <p>Current smoker</p> Signup and view all the answers

    What is the post-Nodify CDT risk of malignancy for the patient?

    <p>85%</p> Signup and view all the answers

    What is the purpose of the Nodify XL2 test?

    <p>To identify patients with likely benign lung nodules</p> Signup and view all the answers

    What is the significance of the specificity of the Nodify CDT test?

    <p>It reflects the performance of the High Level result</p> Signup and view all the answers

    What is the timeframe for receiving Nodify CDT test results?

    <p>One day</p> Signup and view all the answers

    What is the relationship between the pre-test risk of malignancy and the post-Nodify CDT risk of malignancy?

    <p>The post-Nodify CDT risk is higher</p> Signup and view all the answers

    What is the benefit of using the Nodify CDT test?

    <p>All of the above</p> Signup and view all the answers

    Study Notes

    Nodify Lung Testing

    • 95% of lung nodules are benign.
    • Current diagnostic pathways for 8-30 mm lung nodules involve CT surveillance, biopsy, or surgery, with 62% of biopsies and 35% of surgeries on benign nodules.
    • Nodify lung testing is a blood-based testing strategy to help reclassify the risk of malignancy in lung nodules.
    • The test measures autoantibodies associated with lung cancer to detect lung cancer across histologies and stages.

    Clinical Risk Factors

    • Location
    • Spiculation
    • Smoking history
    • Age
    • Nodule size

    Nodify CDT Test

    • Designed to help identify patients with likely malignant lung nodules.
    • Measures autoantibodies to tumor-associated antigens (P53, CAGE, NY-ESO-1, GBU4-5, MAGE A4, SOX2, HuD).
    • Results are presented as a personalized risk of malignancy to support shared decision making and reduce patient anxiety.

    Nodify XL2 Test

    • Designed to help identify patients with likely benign lung nodules.
    • Detects plasma protein levels associated with lung cancer.
    • Results are presented as a personalized risk of malignancy.

    Nodify Lung Results

    • 85% of reported results are likely benign.
    • 10% of reported results are reduced risk.
    • 5% of reported results are high risk.
    • Results can be easily incorporated into clinical workflows.

    Ordering and Receiving Results

    • Order Nodify lung testing for patients with solitary or multiple nodules.
    • Receive results in one day or one week, depending on the test.
    • Use the results to inform care plans, including CT surveillance, biopsy, or surgery.

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    Description

    Identify patients and order tests to receive results with NODIFY LUNG. This quiz helps you understand how to incorporate lung disease identification into clinical workflows.

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