12 Questions
What is the full form of CAC in the context of the text?
Circulating genetically abnormal cell
What is the abbreviation for computed tomography used in the text?
CT
Which high-risk populations can benefit from screening with LDCT according to the text?
High-risk populations for lung cancer
What is one limitation mentioned in the text regarding CT examination for pulmonary nodules?
CT can't distinguish between benign and malignant nodules
What has emerged as a promising liquid biopsy marker with improved diagnostic performance compared to other markers?
CAC (Circulating genetically abnormal cell)
In which cluster of patients did the AUC of CACs perform better than the overall patients?
Cluster 1
What were the independent risk factors for malignant lung nodules in Cluster 1?
CACs, female, maximum nodule type, and maximum nodule size
What does the diagnostic model for lung nodules use as predictors?
CACs, sex, maximum nodule type, and maximum nodule size
How is the probability of malignancy calculated in the established diagnostic model?
probability of malignancy = 1 / (1 + e^-Y)
What was the AUC value of the diagnostic model for lung nodules?
0.925
At what Youden index value was the optimal cut-off value determined?
0.752
What was the sensitivity of the diagnostic model at the optimal cut-off value?
0.786
Test your knowledge on lung cancer screening, diagnostic markers, and early-stage presentation. Learn about the effectiveness of CT examination in detecting pulmonary nodules and reducing mortality rates in high-risk populations.
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