Lorazepam Flashcards
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Questions and Answers

What is the trade name for Lorazepam?

  • Ativan (correct)
  • Xanax
  • Serax
  • Valium

What classification does Lorazepam fall under?

Anxiolytic, benzodiazepine, sedative-hypnotic

What is the FDA category for Lorazepam?

D/C-IV

What are the therapeutic uses of Lorazepam?

<p>Treats insomnia, relieves anxiety, eases alcohol withdrawal</p> Signup and view all the answers

How does Lorazepam work on a molecular level?

<p>Binds to an allosteric site on GABA-A receptors</p> Signup and view all the answers

Lorazepam can be administered __________.

<p>Oral, IM, IV, rectal</p> Signup and view all the answers

What are common side effects of Lorazepam?

<p>Sedation, CNS depression, confusion, depression, nausea</p> Signup and view all the answers

Lorazepam is contraindicated in __________.

<p>Pregnancy, sleep apnea</p> Signup and view all the answers

What nursing considerations should be taken when administering Lorazepam?

<p>Use caution in suicidal patients, taper gradually when discontinued.</p> Signup and view all the answers

What should be assessed before administering Lorazepam?

<p>Determine nature of sleep disturbance, assess underlying cause</p> Signup and view all the answers

What patient teaching should be provided regarding Lorazepam?

<p>Educate patient about sleep fitness, take with food.</p> Signup and view all the answers

Study Notes

Lorazepam Overview

  • Generic name: Lorazepam; trade name: Ativan.
  • Classified as an anxiolytic, benzodiazepine, and sedative-hypnotic.

FDA Classification

  • Classified under D/C-IV, indicating controlled substance status.

Therapeutic Uses

  • Effectively treats insomnia and relieves anxiety.
  • Used to ease alcohol withdrawal symptoms.

Mechanism of Action

  • Functions by binding to an allosteric site on GABA-A receptors, which are pentameric ionotropic receptors located in the central nervous system.

Dosage and Administration

  • Available forms: Oral, intramuscular (IM), intravenous (IV), and rectal routes.
  • Recommended intermittent dosing ranges from 2-6mg orally for optimal effect.

Common Side Effects

  • Notable side effects include sedation, central nervous system (CNS) depression, confusion, depression, and nausea.

Contraindications and Interactions

  • Contraindicated in pregnancy and individuals with sleep apnea.

Nursing Considerations

  • Caution advised for patients with suicidal ideation; taper dosage gradually when discontinuing.
  • Dosage adjustments are necessary for patients with hepatic or renal impairment.
  • IM administration should be deep into the muscle; IV injections may lead to life-threatening side effects.

Pre-Administration Assessment

  • Assess the nature of the patient's sleep disturbance and identify any underlying causes.

Patient Teaching

  • Inform patients about the importance of sleep hygiene and recommend taking the medication with food.
  • Advise reporting any blurred vision, chest pain, or fainting to healthcare providers.

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Description

This quiz provides essential information on Lorazepam, including its generic name, classification, FDA category, therapeutic uses, and mechanism of action. It serves as a great resource for students and professionals looking to reinforce their knowledge about this medication.

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