Questions and Answers
Which of the following tests are associated with functionality?
Albumin
Which tests are useful biomarkers of liver injury?
Alanine transaminase (ALT or SGPT)
Which tests are linked to conditions associated with the biliary tract?
Gamma-glutamyl transferase
Which tests are associated with cellular integrity?
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Which tests are more accurately referred to as liver chemistries or liver tests rather than liver function tests?
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Study Notes
Liver Function Tests
- Functionality tests: Include AST, ALT, and GGT, which are associated with the liver's synthetic and metabolic functions.
- Liver injury biomarkers: AST, ALT, and LDH are useful biomarkers to assess liver injury or damage.
- Biliary tract conditions: Alkaline phosphatase, gamma-glutamyl transferase (GGT), and 5'-nucleotidase are linked to conditions associated with the biliary tract, such as obstruction or inflammation.
- Cellular integrity tests: AST and LDH are associated with cellular integrity, as they are released into the bloodstream when liver cells are damaged.
- Liver chemistries or liver tests: Tests like bilirubin, albumin, and prothrombin time are more accurately referred to as liver chemistries or liver tests, rather than liver function tests, as they measure the liver's synthetic and metabolic functions.
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