COPY: Liver Function Tests and Jaundice Quiz

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Which of the following is NOT a function of the liver?

Production of red blood cells (correct)

Formation of bile

Excretion of nitrogen

Protein biosynthesis

Jaundice is characterized by an abnormally low plasma concentration of bilirubin.

False

What percentage of blood supply to the liver comes from the hepatic artery?

30

The liver is the main site of ______ which produces glucose from non-carbohydrate sources.

gluconeogenesis Signup and view all the answers

Match the following liver functions with their descriptions:

Excretion of nitrogen = Produces urea Protein biosynthesis = Produces albumin and clotting factors Drug metabolism = Processes and modifies various drugs Formation of bile = Includes bile salts and bilirubin Signup and view all the answers

What condition is associated with markedly increased unconjugated bilirubin in the blood?

Prehepatic jaundice Signup and view all the answers

In prehepatic jaundice, there is bilirubin present in the urine.

False Signup and view all the answers

What substance is formed when hemoglobin is broken down?

bilirubin Signup and view all the answers

Prehepatic jaundice results in an increase of ________ bilirubin in the blood.

unconjugated Signup and view all the answers

Match the following bilirubin types with their characteristics:

Unconjugated bilirubin = Not water soluble, bound to albumin Conjugated bilirubin = Water soluble, can be excreted in urine Urobilinogen = Intermediate product in bilirubin metabolism Bilirubin-diglucuronide = Conjugated form of bilirubin in the liver Signup and view all the answers

What color urine is typically observed in prehepatic jaundice?

Orange Signup and view all the answers

Urobilinogen is water soluble and can be excreted in urine.

True Signup and view all the answers

What is the main role of the liver in bilirubin metabolism?

conjugation of bilirubin Signup and view all the answers

Which reagent is used to detect substances in the context of liver conditions?

Erlich’s reagent Signup and view all the answers

Cirrhosis of the liver can occur as a result of chronic alcohol consumption.

True Signup and view all the answers

What is the primary enzyme indicator that comes up first in cases of hepatocellular damage?

alanine aminotransferase (ALT) Signup and view all the answers

Gamma glutamyl transferase is primarily derived from the ______ system.

hepatobiliary Signup and view all the answers

Match the liver conditions with their characteristics:

Prehepatic jaundice = Large amounts of stercobilinogen in the stools Hepatocellular damage = Viruses such as Hepatitis A, B, and C Cirrhosis = Nodular liver surface and yellow/green color Non-alcoholic fatty liver disease (NAFLD) = Fatty liver without inflammation Signup and view all the answers

Which of the following factors is NOT commonly associated with hepatocellular damage?

Cholesterol levels Signup and view all the answers

The sequence of events leading to cirrhosis includes injury, inflammation, cell death, ______, and regeneration.

fibrosis Signup and view all the answers

Alanine aminotransferase (ALT) is specific to liver disease.

False Signup and view all the answers

What is the normal range for albumin in g/l?

36 - 47 Signup and view all the answers

Alkaline phosphatase is considered a great standalone biomarker for liver function.

False Signup and view all the answers

What does an increase in alanine aminotransferase levels typically indicate?

Hepatocellular damage Signup and view all the answers

The liver can be subjected to numerous conditions, and a battery of tests is vital to diagnose ______ abnormalities.

liver Signup and view all the answers

Match the liver tests with their normal ranges:

Albumin = 36 - 47 g/l Alkaline Phosphatase = 40 - 125 u/l Alanine Aminotransferase = 10 - 40 u/l Gamma Glutamyl Transferase = 10 - 35 u/l Signup and view all the answers

Which biochemical test indicates cholestatic liver disease by showing elevation?

Alkaline phosphatase Signup and view all the answers

The biological half-life of albumin is approximately 10 days.

False Signup and view all the answers

What type of bilirubin is primarily elevated in cholestatic liver disease?

Conjugated bilirubin Signup and view all the answers

Primary biliary cirrhosis is a __________ condition that commonly affects women in mid-life.

chronic autoimmune Signup and view all the answers

Match the following liver conditions with their characteristics:

Cholestatic liver disease = Failure of bile to reach the duodenum Primary sclerosing cholangitis = Chronic condition associated with ulcerative colitis Cirrhosis = Scarring and damage to liver tissue Fatty liver = Accumulation of fat in liver cells Signup and view all the answers

What is the primary immune response marker for hepatitis B infection?

HBs Ag Signup and view all the answers

Bilirubin is not detectable in urine during significant biliary obstruction.

True Signup and view all the answers

Drug-induced cholestatic liver disease can occur due to __________ agents.

several antibiotic Signup and view all the answers

What is the role of albumin in bilirubin transport?

It binds to unconjugated bilirubin in the bloodstream. Signup and view all the answers

Urobilinogen is formed in the small intestine after bilirubin enters the gut.

True Signup and view all the answers

What virus was the 21-year-old student infected with after returning from Asia?

hepatitis virus type A Signup and view all the answers

The _____ vein carries bilirubin from the spleen to the liver.

portal Signup and view all the answers

Match the following substances with their descriptions:

Conjugated Bilirubin = Water-soluble form of bilirubin Unconjugated Bilirubin = Bound to albumin for transport Urobilinogen = Product formed in the intestine from bilirubin Bilirubin Diglucuronide = Conjugated form of bilirubin for excretion Signup and view all the answers

Which combination of tests is considered more effective?

A panel of tests including bilirubin and liver function markers. Signup and view all the answers

Bilrubin must be excreted through urine before forming urobilinogen.

False Signup and view all the answers

In the case of jaundice, what is the primary substance that is elevated in urine?

bilirubin Signup and view all the answers

COPY: Liver Function Tests and Jaundice Quiz

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Questions and Answers

Which of the following is NOT a function of the liver?

Jaundice is characterized by an abnormally low plasma concentration of bilirubin.

What percentage of blood supply to the liver comes from the hepatic artery?

The liver is the main site of ______ which produces glucose from non-carbohydrate sources.

Match the following liver functions with their descriptions:

What condition is associated with markedly increased unconjugated bilirubin in the blood?

In prehepatic jaundice, there is bilirubin present in the urine.

What substance is formed when hemoglobin is broken down?

Prehepatic jaundice results in an increase of ________ bilirubin in the blood.

Match the following bilirubin types with their characteristics:

What color urine is typically observed in prehepatic jaundice?

Urobilinogen is water soluble and can be excreted in urine.

What is the main role of the liver in bilirubin metabolism?

Which reagent is used to detect substances in the context of liver conditions?

Cirrhosis of the liver can occur as a result of chronic alcohol consumption.

What is the primary enzyme indicator that comes up first in cases of hepatocellular damage?

Gamma glutamyl transferase is primarily derived from the ______ system.

Match the liver conditions with their characteristics:

Which of the following factors is NOT commonly associated with hepatocellular damage?

The sequence of events leading to cirrhosis includes injury, inflammation, cell death, ______, and regeneration.

Alanine aminotransferase (ALT) is specific to liver disease.

What is the normal range for albumin in g/l?

Alkaline phosphatase is considered a great standalone biomarker for liver function.

What does an increase in alanine aminotransferase levels typically indicate?

The liver can be subjected to numerous conditions, and a battery of tests is vital to diagnose ______ abnormalities.

Match the liver tests with their normal ranges:

Which biochemical test indicates cholestatic liver disease by showing elevation?

The biological half-life of albumin is approximately 10 days.

What type of bilirubin is primarily elevated in cholestatic liver disease?

Primary biliary cirrhosis is a __________ condition that commonly affects women in mid-life.

Match the following liver conditions with their characteristics:

What is the primary immune response marker for hepatitis B infection?

Bilirubin is not detectable in urine during significant biliary obstruction.

Drug-induced cholestatic liver disease can occur due to __________ agents.

What is the role of albumin in bilirubin transport?

Urobilinogen is formed in the small intestine after bilirubin enters the gut.

What virus was the 21-year-old student infected with after returning from Asia?

The _____ vein carries bilirubin from the spleen to the liver.

Match the following substances with their descriptions:

Which combination of tests is considered more effective?

Bilrubin must be excreted through urine before forming urobilinogen.

In the case of jaundice, what is the primary substance that is elevated in urine?

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