Liver Function Test
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Questions and Answers

What are some of the functions of the liver in metabolism?

Metabolism of carbohydrates, lipids, and proteins

What substances does the liver excrete?

Bilirubin, bile acids, and bile salts

What does the liver synthesize?

Albumin, α- and β-globulins, clotting factors, cholesterol, lipoproteins

What does the liver store?

<p>Glycogen, vitamins (A, D, B12), etc.</p> Signup and view all the answers

Why is the liver considered a vital organ in the body?

<p>Due to its multiple functions such as metabolism, excretion, synthesis, and storage</p> Signup and view all the answers

What is the purpose of Liver Function Tests?

<p>To assess the functional capacity of the liver.</p> Signup and view all the answers

Why are Liver Function Tests important?

<p>They help in diagnosing liver diseases and monitoring the effectiveness of treatments.</p> Signup and view all the answers

What do Liver Function Tests measure?

<p>They measure levels of enzymes, proteins, and bilirubin in the blood.</p> Signup and view all the answers

How do Liver Function Tests help in clinical practice?

<p>They aid in the early detection of liver problems before symptoms appear.</p> Signup and view all the answers

What are some common enzymes measured in Liver Function Tests?

<p>AST, ALT, and ALP are commonly measured enzymes.</p> Signup and view all the answers

How do liver function tests aid in the management of liver disease?

<p>Liver function tests help in the management of liver disease by allowing clinicians to detect and diagnose liver disease, evaluate its severity, monitor the response to treatment, and assess the prognosis.</p> Signup and view all the answers

Explain the role of liver function tests in the context of detoxification and drug metabolism.

<p>Liver function tests are important in evaluating the liver's capacity for <em>detoxification and drug metabolism</em>, which are crucial liver functions. These tests can help detect and monitor liver disease that may impair these vital liver processes.</p> Signup and view all the answers

What are the main purposes of liver function tests?

<p>The main purposes of liver function tests are to detect and diagnose liver disease, evaluate the severity of liver disease, monitor response to therapy, and assess the prognosis of liver disease.</p> Signup and view all the answers

Discuss how liver function tests can be used to assess the prognosis of liver disease.

<p>Liver function tests can provide information about the severity and progression of liver disease, which in turn can be used to assess the prognosis. Abnormal or worsening liver function test results may indicate a poorer prognosis, while improvements can suggest a better outlook.</p> Signup and view all the answers

Suppose a patient is undergoing treatment for a liver condition. How can liver function tests help monitor the response to therapy?

<p>Liver function tests can be used to monitor the patient's response to treatment for a liver condition. Improvements in liver enzyme levels or other markers over time would indicate that the therapy is effective, while persistent or worsening abnormalities could suggest the need to adjust the treatment plan.</p> Signup and view all the answers

What physiological conditions can abnormal bilirubin levels indicate?

<p>Liver or bile duct problems, jaundice, or anemia.</p> Signup and view all the answers

If a patient exhibits jaundice, what type of abnormal bilirubin level would they likely have?

<p>Elevated bilirubin levels</p> Signup and view all the answers

What organ systems are primarily involved in the conditions mentioned related to abnormal bilirubin levels?

<p>The hepatic (liver) system and hematologic (blood) system.</p> Signup and view all the answers

If a patient has obstructed bile ducts, how would this affect their bilirubin levels?

<p>Their bilirubin levels would likely be elevated.</p> Signup and view all the answers

What is the primary function of bilirubin in the body, and how does an abnormal level disrupt this function?

<p>Bilirubin is a waste product from the breakdown of red blood cells. Abnormal levels indicate a disruption in the production, metabolism, or excretion of bilirubin.</p> Signup and view all the answers

What is the primary difference between obstructive and unconjugated jaundice?

<p>Obstructive jaundice is caused by an obstruction in the bile duct system, leading to a buildup of conjugated bilirubin, while unconjugated jaundice is caused by an overproduction or impaired conjugation of bilirubin, resulting in an accumulation of unconjugated bilirubin.</p> Signup and view all the answers

Explain the role of bilirubin conjugation in the development of jaundice.

<p>Bilirubin conjugation is a process where bilirubin, a waste product from the breakdown of hemoglobin, is made water-soluble by the liver through the addition of glucuronic acid. Impaired conjugation can lead to an accumulation of unconjugated bilirubin, resulting in unconjugated jaundice.</p> Signup and view all the answers

What is the primary function of a bilirubin test, and how does it aid in the diagnosis of jaundice?

<p>A bilirubin test measures the levels of bilirubin in the blood. High levels of total bilirubin, or an elevated proportion of conjugated or unconjugated bilirubin, can indicate the presence and type of jaundice, aiding in the diagnosis and guiding further investigations.</p> Signup and view all the answers

Describe the potential consequences of prolonged obstructive jaundice if left untreated.

<p>If obstructive jaundice is left untreated, it can lead to serious complications such as cholangitis (inflammation of the bile ducts), gallstones, liver damage, and potentially liver failure due to the buildup of toxic bile components.</p> Signup and view all the answers

Explain the physiological mechanisms involved in the excretion of bilirubin from the body.

<p>Bilirubin is excreted from the body through the following process: unconjugated bilirubin is taken up by liver cells, conjugated with glucuronic acid, and then secreted into the bile. The conjugated bilirubin is then eliminated from the body through the feces after being metabolized by intestinal bacteria.</p> Signup and view all the answers

Study Notes

Liver Functions

  • Liver plays a crucial role in metabolism of carbohydrates, lipids, and proteins
  • It carries out excretion of bilirubin, bile acids, and bile salts
  • It synthesizes albumin, α- and β-globulins, clotting factors, cholesterol, and lipoprotein
  • It stores glycogen, vitamins (A, D, B12), and other essential nutrients

Bilirubin Test

  • A bilirubin test measures the levels of bilirubin in the blood
  • Abnormal levels of bilirubin may indicate liver or bile duct problems, jaundice, or anemia

Liver Function Tests (LFTs)

  • LFTs are used to assess the functional capacity of the liver
  • LFTs are used to: • Detect and diagnose liver disease • Evaluate the severity of liver disease • Monitor response to therapy • Assess prognosis of liver disease

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Learn about liver function tests which are conducted to evaluate the functional capacity of the liver through various assessments.

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