Liver Function & Disease 3

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What are the common causes of acute inflammation of the liver?

Alcohol, paracetamol, or fungal toxins.

What are the chemical markers used to detect hepatocellular carcinoma and germ cell tumors?

a-Fetoprotein.

What is the common cause of Non-alcoholic fatty liver disease (NAFLD)?

Obesity and diabetes.

What are the functions of the liver and how do liver function tests serve as diagnostic tools for acute liver failure?

The liver is responsible for synthesizing vitamin K-dependent clotting factors and regulating glucose metabolism. Liver function tests, such as plasma bilirubin levels and international normalized ratio, serve as effective diagnostic tools in acute liver failure.

What are some causes of acute hepatitis and what are the potential consequences?

Acute hepatitis can develop due to various causes, including alcohol, paracetamol intoxication, or fungal toxins, and can result in severe liver dysfunction and increased prothrombin time.

What are the risk factors for non-alcoholic fatty liver disease (NAFLD) and what are some other liver diseases that can impact liver function and lead to liver failure?

Obesity and diabetes are common risk factors for NAFLD. Other liver diseases, such as primary biliary cirrhosis, cholestasis, and cirrhosis, can also impact liver function and lead to liver failure if left untreated.

What is the purpose of the Model for End-Stage Liver Disease (MELD)?

To determine the severity of liver diseases.

What are some factors generally associated with advanced liver disease?

Chronic infection with hepatitis B or C, alcohol consumption, and elevated plasma aminotransferases.

What diagnostic tools can aid in diagnosing liver conditions?

Non-invasive tools such as ultrasound examination and endoscopic retrograde cholangiopancreatography.

What is the most common outcome of acute hepatitis and what does it lead to?

The most common outcome of acute hepatitis is the development of acute liver failure, leading to impaired liver functions and even death.

What measures are needed to manage acute hepatitis and what should be monitored?

General supportive measures are needed to manage acute hepatitis, along with liver function monitoring.

What are two independent liver conditions that can impact liver function?

Wilson's disease and hemochromatosis are two independent liver conditions that can impact liver function.

What is the role of A-Fetoprotein in diagnosing liver diseases?

A-Fetoprotein serves as a marker for hepatocellular carcinoma and germ cell tumors.

What are some non-invasive diagnostic tools used to diagnose liver conditions?

Ultrasound examination and endoscopic retrograde cholangiopancreatography are non-invasive diagnostic tools used to diagnose liver conditions.

What are Wilson's disease and hemochromatosis?

Wilson's disease and hemochromatosis are independent liver conditions that can impact liver function.

What is A-Fetoprotein and how is it used in diagnosing liver conditions?

A-Fetoprotein is a glycoprotein that is undetectable in healthy individuals and is used as a marker for hepatocellular carcinoma and germ cell tumors.

What are some causes of liver diseases and what diagnostic tools are used to diagnose them?

Liver diseases can be caused by factors such as alcohol, infection, and obesity. Non-invasive diagnostic tools such as ultrasound examination and endoscopic retrograde cholangiopancreatography are used to diagnose liver conditions, while liver function tests are essential in diagnosing acute liver failure.

What are Wilson's disease and hemochromatosis, and how do they impact liver function?

Wilson's disease and hemochromatosis are independent liver conditions that can impact liver function. They can cause damage to the liver and lead to fibrosis, liver dysfunction, and even liver failure.

What is the difference between acute hepatitis and acute liver failure?

Acute hepatitis is an inflammation of the liver lasting less than 6 months, while acute liver failure is severe liver dysfunction developed within 6 months of onset due to toxins or viruses.

What are the relevant terms in liver diseases?

Relevant terms include 'Compensated,' 'Decompensated,' ascites, jaundice, and Hepatic Encephalopathy.

What causes fulminant hepatic failure?

Fulminant hepatic failure is severe hepatic dysfunction due to Paracetamol overdose, hepatitis viruses B and E, or Amanita mushroom poisoning.

Question 1

What is the difference between alcohol liver disease and non-alcoholic fatty liver disease, and what are their common causes?

Answer 1

Alcohol liver disease progresses from necrosis to cirrhosis, while non-alcoholic fatty liver disease ranges from steatosis to chronic liver disease. The common causes of non-alcoholic fatty liver disease are obesity and diabetes.

Question 2

What is cholestasis and how is primary biliary cirrhosis detected?

Answer 2

Cholestasis obstructs bile flow, and primary biliary cirrhosis is detected with anti-mitochondrial antibodies.

Question 3

What is the significance of a-fetoprotein in hepatic tumours?

Answer 3

A-fetoprotein is used as a marker for hepatocellular carcinoma and germ cell tumours, as hepatic tumours activate stem cells.

"Test Your Knowledge on Liver Functions and Diseases" - Take this quiz to assess your understanding of the liver's role in producing clotting factors, performing biochemical testing, and diagnosing common conditions. Learn about the causes and detection of acute liver inflammation caused by alcohol, paracetamol, or fungal toxins. Challenge yourself with questions on the biochemical changes that occur in liver diseases. Sharpen your knowledge on liver functions with this informative quiz.

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