Liver Function & Disease 3

Alcohol, paracetamol, or fungal toxins.

a-Fetoprotein.

Obesity and diabetes.

<p>The liver is responsible for synthesizing vitamin K-dependent clotting factors and regulating glucose metabolism. Liver function tests, such as plasma bilirubin levels and international normalized ratio, serve as effective diagnostic tools in acute liver failure.</p> Signup and view all the answers

<p>Acute hepatitis can develop due to various causes, including alcohol, paracetamol intoxication, or fungal toxins, and can result in severe liver dysfunction and increased prothrombin time.</p> Signup and view all the answers

<p>Obesity and diabetes are common risk factors for NAFLD. Other liver diseases, such as primary biliary cirrhosis, cholestasis, and cirrhosis, can also impact liver function and lead to liver failure if left untreated.</p> Signup and view all the answers

<p>To determine the severity of liver diseases.</p> Signup and view all the answers

<p>Chronic infection with hepatitis B or C, alcohol consumption, and elevated plasma aminotransferases.</p> Signup and view all the answers

<p>Non-invasive tools such as ultrasound examination and endoscopic retrograde cholangiopancreatography.</p> Signup and view all the answers

<p>The most common outcome of acute hepatitis is the development of acute liver failure, leading to impaired liver functions and even death.</p> Signup and view all the answers

<p>General supportive measures are needed to manage acute hepatitis, along with liver function monitoring.</p> Signup and view all the answers

<p>Wilson's disease and hemochromatosis are two independent liver conditions that can impact liver function.</p> Signup and view all the answers

<p>A-Fetoprotein serves as a marker for hepatocellular carcinoma and germ cell tumors.</p> Signup and view all the answers

<p>Ultrasound examination and endoscopic retrograde cholangiopancreatography are non-invasive diagnostic tools used to diagnose liver conditions.</p> Signup and view all the answers

<p>Wilson's disease and hemochromatosis are independent liver conditions that can impact liver function.</p> Signup and view all the answers

<p>A-Fetoprotein is a glycoprotein that is undetectable in healthy individuals and is used as a marker for hepatocellular carcinoma and germ cell tumors.</p> Signup and view all the answers

<p>Liver diseases can be caused by factors such as alcohol, infection, and obesity. Non-invasive diagnostic tools such as ultrasound examination and endoscopic retrograde cholangiopancreatography are used to diagnose liver conditions, while liver function tests are essential in diagnosing acute liver failure.</p> Signup and view all the answers

<p>Wilson's disease and hemochromatosis are independent liver conditions that can impact liver function. They can cause damage to the liver and lead to fibrosis, liver dysfunction, and even liver failure.</p> Signup and view all the answers

<p>Acute hepatitis is an inflammation of the liver lasting less than 6 months, while acute liver failure is severe liver dysfunction developed within 6 months of onset due to toxins or viruses.</p> Signup and view all the answers

<p>Relevant terms include 'Compensated,' 'Decompensated,' ascites, jaundice, and Hepatic Encephalopathy.</p> Signup and view all the answers

<p>Fulminant hepatic failure is severe hepatic dysfunction due to Paracetamol overdose, hepatitis viruses B and E, or Amanita mushroom poisoning.</p> Signup and view all the answers

<p>What is the difference between alcohol liver disease and non-alcoholic fatty liver disease, and what are their common causes?</p> Signup and view all the answers

<p>Alcohol liver disease progresses from necrosis to cirrhosis, while non-alcoholic fatty liver disease ranges from steatosis to chronic liver disease. The common causes of non-alcoholic fatty liver disease are obesity and diabetes.</p> Signup and view all the answers

<p>What is cholestasis and how is primary biliary cirrhosis detected?</p> Signup and view all the answers

<p>Cholestasis obstructs bile flow, and primary biliary cirrhosis is detected with anti-mitochondrial antibodies.</p> Signup and view all the answers

<p>What is the significance of a-fetoprotein in hepatic tumours?</p> Signup and view all the answers

<p>A-fetoprotein is used as a marker for hepatocellular carcinoma and germ cell tumours, as hepatic tumours activate stem cells.</p> Signup and view all the answers