Liver Diseases Quiz

The liver removes excess ______ from the bloodstream and stores it as glycogen.

Drug-induced liver injury (DILI) is common and nearly all classes of ______ can cause liver disease.

Most cases of DILI are benign, and improve after ______ withdrawal.

Pre-existing liver disease and genetic ______ may predispose certain individuals to DILI.

Steatosis is accumulation of abnormal amount of ______ within hepatocytes.

Steatosis is a result of imbalance between rate of synthesis & release of these lipids by ______ into circulation.

Inability to export copper into ______ is a central problem in Wilson's disease.

A defect in ______ results in excessive copper accumulation in HPCs.

Ethanol ______ is among the major causes of liver disease in Western countries.

The early stage of ethanol abuse is associated with hepatic ______ accumulation.

As alcohol-induced liver disease progresses, appreciable cell ______ occurs alongside increasing hepatic inflammation.

People with hepatic ______ due to chronic alcohol abuse frequently become deficient at detoxifying both the ammonia and bilirubin.

Fibrotic tissue Chronic type of liver injury, usually results from long-term & multiple exposures to toxic chemicals that cause destruction to the hepatic cells with replacement by ______ fibers.

Cirrhosis is an irreversible damage result mainly from alcohol-induced fatty liver & has a poor prognosis of survival. It is a type of ______ injury.

Cholestasis is characterized by reduction or block in bile flow leading to an increase in the level of particularly bile acids & bilirubin in the blood due to either hepatic disorders (Canalicular) or biliary duct damage (cholangiodestructive). It results from the reduced or blocked flow of ______ from your liver.

Hepatitis is caused by many factors including drugs, toxins, bacteria & viruses. It is characterized by the emigration of neutrophils, lymphocytes & other inflammatory cells into the region of damaged hepatocytes. Immunoresponse of liver cells to some types of chemical agents can result after their biotransformation, binding with liver proteins & leak out of injured hepatocytes serve as an antigen that stimulates the production of antibodies. Hepatitis could be an acute or ______ type.

Tumor of hepatic tissue caused by chemicals that undergo metabolic conversion to more toxic intermediates. They exert their carcinogenicity by interaction with nuclear materials, mainly the DNA, resulting in alterations in the genetic machinery causing mutations & initiation of a chain of events that result in cancer formation is known as ______.

Viral hepatitis is a type of hepatitis that is caused by ______.