Podcast
Questions and Answers
What is the end point of progressive damage to the liver?
What is the end point of progressive damage to the liver?
What is a life-threatening consequence of hepatic failure?
What is a life-threatening consequence of hepatic failure?
In full-blown hepatic failure, what percentage of patients may recover spontaneously?
In full-blown hepatic failure, what percentage of patients may recover spontaneously?
What is the treatment for acute or chronic liver failure?
What is the treatment for acute or chronic liver failure?
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Which category of liver failure involves massive hepatic necrosis?
Which category of liver failure involves massive hepatic necrosis?
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Primary liver diseases are caused by heart failure, diabetes, and extrahepatic infections.
Primary liver diseases are caused by heart failure, diabetes, and extrahepatic infections.
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Hepatic failure results in the loss of 70% to 80% of hepatic function.
Hepatic failure results in the loss of 70% to 80% of hepatic function.
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Full-blown hepatic failure leads to death in 80% of patients within weeks to a few months.
Full-blown hepatic failure leads to death in 80% of patients within weeks to a few months.
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Acute liver failure is the most common category of liver failure.
Acute liver failure is the most common category of liver failure.
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Liver transplantation is not a treatment option for acute or chronic liver failure.
Liver transplantation is not a treatment option for acute or chronic liver failure.
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Study Notes
Liver Diseases Overview
- The human liver weighs around 1500g and makes up about 2% of total body weight, located under the diaphragm on the right side of the abdomen.
- The liver plays a crucial role in maintaining metabolic homeostasis, including albumin and bile production, blood filtration, amino acid regulation, blood clotting, resistance to infections, vitamin and mineral storage, and glucose processing.
- Surgical removal of 60% of the liver in a normal person results in minimal and transient hepatic impairment, with most of its mass restored through regeneration within 4 to 6 weeks.
- The liver is vulnerable to a wide range of metabolic, toxic, microbial, and circulatory insults, leading to various liver diseases, including primary and secondary diseases related to heart failure, diabetes, and extrahepatic infections.
- Hepatic failure is the end point of progressive liver damage, resulting in the destruction of hepatocytes or parenchymal damage and the loss of 80% to 90% of hepatic function.
- Hepatic failure is life-threatening due to the accumulation of toxic metabolites, respiratory failure, coagulopathy, systemic infections, sepsis, renal failure, and electrolyte disturbances.
- Full-blown hepatic failure leads to 80% death within weeks to a few months, while 40% of patients with acute liver failure may recover spontaneously.
- Liver transplantation is a treatment option in acute or chronic liver failure, which can be categorized into acute liver failure with massive hepatic necrosis, chronic liver diseases, and hepatocellular carcinoma.
- Liver diseases are a significant focus in the Department of Biomedical Sciences' Systemic Pathology course, with course code 3401203, offered in Semester 1 of Year 3 for Batch 22 students, taught by Nada Suliman, BDS, MPH, PHD, with a class date of 14/11/2023 at 1445AH.
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Description
Test your knowledge of liver diseases with this quiz. Topics covered include the structure and function of the liver, as well as its role in maintaining metabolic homeostasis.
