Liver Diseases: CAH, EHBT, IHBT, Reye's Syndrome
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Questions and Answers

Which type of obstruction is associated with elevated B2 levels and elevated ALP & B2?

  • Intrahepatic Biliary Obstruction
  • Laennec’s cirrhosis
  • Extrahepatic Biliary Obstruction (correct)
  • Pancreatitis
  • In which condition is AST greater than ALT, and ALP is very high?

  • Granulomatous/Neoplastic Diseases
  • Biliary cirrhosis
  • Alcoholic fatty liver
  • Laennec’s cirrhosis (correct)
  • Which disease is specifically associated with Anti Mitochondrial Ab (AMA) and attacks the biliary tract?

  • Reye's syndrome
  • Biliary cirrhosis (correct)
  • Alcoholic Hepatitis
  • Chronic Active Hepatitis
  • Which condition results in high lipase & amylase levels in liver function tests?

    <p>Pancreatitis</p> Signup and view all the answers

    In which condition is ALT greater than AST and declines with steroids?

    <p>Chronic Active Hepatitis</p> Signup and view all the answers

    Which condition leads to a decrease in synthetic function and portal hypertension?

    <p>Laennec’s cirrhosis</p> Signup and view all the answers

    Why does the ALT level have minimal increase during Chronic Hep C?

    <p>Because ALTs are confined inside the vacuoles of the cells and there is no leakage of cell components</p> Signup and view all the answers

    What condition can lead to minimal increase in ALT levels in the liver?

    <p>Fatty liver</p> Signup and view all the answers

    Which liver condition is characterized by normal AST & ALT levels and fibrosis instead of necrosis?

    <p>Cirrhosis</p> Signup and view all the answers

    In which situation is ALT considered to be a good marker for liver cell necrosis?

    <p>Toxic/Ischemic injury</p> Signup and view all the answers

    What is a distinguishing feature of liver function tests in Severe Alcoholic Hepatitis?

    <p>Elevated AST levels higher than ALT levels</p> Signup and view all the answers

    What is a common cause of elevated transaminases in asymptomatic patients with no jaundice?

    <p>Iron, Cu, or A1AT deficiency</p> Signup and view all the answers

    What scenario stimulates an immediate increase in AST and ALT levels in liver function tests?

    <p>Acute hepatitis causing immediate elevation in enzyme levels</p> Signup and view all the answers

    Which condition is associated with normal AST & ALT levels and apoptosis rather than necrosis?

    <p>Chronic Hepatitis C</p> Signup and view all the answers

    What does a De Ritis Ratio value of 2, 4, 5 indicate in liver function tests?

    <p>Alcoholic hepatitis or other conditions with elevated AST compared to ALT</p> Signup and view all the answers

    What happens to the production of transaminases as the liver becomes more fibrotic?

    <p>Decreases</p> Signup and view all the answers

    Why do ALT levels remain relatively stable in Chronic Hepatitis C compared to necrosis?

    <p>'Peklat' helps keep ALT confined inside the cell vacuoles</p> Signup and view all the answers

    In which group of patients would you expect ALT values to not conform to the normal reference range?

    <p>Renal dialysis patients</p> Signup and view all the answers

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