Liver Diseases: CAH, EHBT, IHBT, Reye's Syndrome

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Which type of obstruction is associated with elevated B2 levels and elevated ALP & B2?

Intrahepatic Biliary Obstruction

Laennec’s cirrhosis

Extrahepatic Biliary Obstruction (correct)

Pancreatitis

In which condition is AST greater than ALT, and ALP is very high?

Granulomatous/Neoplastic Diseases

Biliary cirrhosis

Alcoholic fatty liver

Laennec’s cirrhosis (correct)

Which disease is specifically associated with Anti Mitochondrial Ab (AMA) and attacks the biliary tract?

Reye's syndrome

Biliary cirrhosis (correct)

Alcoholic Hepatitis

Chronic Active Hepatitis

Which condition results in high lipase & amylase levels in liver function tests?

Pancreatitis (D) Signup and view all the answers

In which condition is ALT greater than AST and declines with steroids?

Chronic Active Hepatitis (A) Signup and view all the answers

Which condition leads to a decrease in synthetic function and portal hypertension?

Laennec’s cirrhosis (A) Signup and view all the answers

Why does the ALT level have minimal increase during Chronic Hep C?

Because ALTs are confined inside the vacuoles of the cells and there is no leakage of cell components (A) Signup and view all the answers

What condition can lead to minimal increase in ALT levels in the liver?

Fatty liver (D) Signup and view all the answers

Which liver condition is characterized by normal AST & ALT levels and fibrosis instead of necrosis?

Cirrhosis (C) Signup and view all the answers

In which situation is ALT considered to be a good marker for liver cell necrosis?

Toxic/Ischemic injury (A) Signup and view all the answers

What is a distinguishing feature of liver function tests in Severe Alcoholic Hepatitis?

Elevated AST levels higher than ALT levels (D) Signup and view all the answers

What is a common cause of elevated transaminases in asymptomatic patients with no jaundice?

Iron, Cu, or A1AT deficiency (C) Signup and view all the answers

What scenario stimulates an immediate increase in AST and ALT levels in liver function tests?

Acute hepatitis causing immediate elevation in enzyme levels (B) Signup and view all the answers

Which condition is associated with normal AST & ALT levels and apoptosis rather than necrosis?

Chronic Hepatitis C (C) Signup and view all the answers

What does a De Ritis Ratio value of 2, 4, 5 indicate in liver function tests?

Alcoholic hepatitis or other conditions with elevated AST compared to ALT (C) Signup and view all the answers

What happens to the production of transaminases as the liver becomes more fibrotic?

Decreases (C) Signup and view all the answers

Why do ALT levels remain relatively stable in Chronic Hepatitis C compared to necrosis?

'Peklat' helps keep ALT confined inside the cell vacuoles (B) Signup and view all the answers

In which group of patients would you expect ALT values to not conform to the normal reference range?

Renal dialysis patients (A) Signup and view all the answers