Liver Detoxification and Function Tests
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Questions and Answers

Which part of the liver has a primary role in detoxification?

  • Sinusoids
  • Kupffer cells
  • Hepatocytes (correct)
  • Canaliculi
  • What color is urine typically in patients with jaundice?

  • Light green
  • Transparent
  • Dark yellow (correct)
  • Brown
  • What indicates bile duct damage in liver function tests?

  • ALP
  • ALT
  • GGT (correct)
  • AST
  • What happens to albumin levels in liver cirrhosis?

    <p>They decrease</p> Signup and view all the answers

    How does liver dysfunction typically impact PT/INR values?

    <p>Increases them</p> Signup and view all the answers

    Which test is primarily used to monitor the liver function in patients receiving prolonged medication treatments?

    <p>Alanine Aminotransferase (ALT)</p> Signup and view all the answers

    Which parameter is specifically utilized to evaluate the liver's ability to detoxify substances?

    <p>Bilirubin</p> Signup and view all the answers

    What does an increase in both AST and ALT levels typically indicate?

    <p>Liver disease</p> Signup and view all the answers

    In liver function tests, what is the significance of GGT levels?

    <p>Indicator of bile duct damage</p> Signup and view all the answers

    How does liver dysfunction generally affect the levels of albumin in the blood?

    <p>Decreases albumin levels</p> Signup and view all the answers

    Study Notes

    Liver Detoxification and Function Tests

    • Hepatocytes are the primary cells responsible for liver detoxification.
    • ALT (Alanine Aminotransferase) is a key enzyme monitored in patients on long-term medication to track liver function.
    • GGT (Gamma-Glutamyl Transferase) is a key indicator of potential bile duct damage.
    • Dark yellow urine is a typical symptom of jaundice.
    • Serum Creatinine is not usually used to assess liver function, it's more relevant to kidney function.
    • Liver disease can cause elevated levels of both AST (Aspartate Aminotransferase) and ALT.
    • Bilirubin levels are used to assess the liver's detoxifying ability.
    • Albumin levels decrease in cases of liver cirrhosis.
    • ALT is an enzyme that directly participates in amino acid metabolism within the liver.
    • Conjugated bilirubin is water-soluble which makes it easier to excrete through urine.
    • Liver dysfunction often leads to an increase in PT/INR (Prothrombin Time/International Normalized Ratio) values, showing a potential issue with blood coagulation.

    Liver Function Tests

    • Hepatocytes are primarily responsible for detoxification in the liver.
    • ALT (Alanine Transaminase) is used to monitor liver function in patients on long-term medication.
    • GGT (Gamma-Glutamyl Transferase) is an indicator of bile duct damage, often used in liver function tests.
    • Jaundice manifests in dark yellow urine.
    • Serum Creatinine is least likely used to assess liver function, as it primarily reflects kidney function.
    • Liver disease can cause elevated levels of both AST (Aspartate Transaminase) and ALT.
    • Bilirubin is measured to evaluate the liver's detoxifying ability.
    • Liver cirrhosis causes a decrease in albumin levels.
    • ALT is involved in the metabolism of amino acids in the liver.
    • Conjugated bilirubin is water-soluble, unlike unconjugated bilirubin.
    • Liver dysfunction typically increases PT/INR (Prothrombin Time/International Normalized Ratio) values.

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    Description

    This quiz covers essential concepts related to liver detoxification and the function tests used to evaluate liver health. Topics include key enzymes like ALT and GGT, indicators of liver disease, and relevant symptoms such as jaundice. Test your knowledge on the vital role of the liver and the implications of its dysfunction.

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