18 Questions
What is a common cause of large bile duct obstruction?
Gallstones and head of the pancreas malignancies
What is primary biliary cholangitis characterized by?
Autoimmune disease with progressive, inflammatory, granulomatous destruction of small to medium intrahepatic bile ducts
What is the most common cause of impaired intrahepatic blood flow?
Cirrhosis
What is a complication of portal vein obstruction?
Portal hypertension, esophageal varices, and ascites
What is the term for a benign tumor of hepatocytes?
Hepatocellular adenoma
Which of the following is a common site of metastatic cancers?
Liver
What is the primary cause of postrenal azotemia?
Urine flow obstruction
What is the term for the daily protein loss in the urine of 3.5g and more?
Proteinuria
What is the most common form of glomerulonephritis caused by the formation of immune complexes?
Granular pattern of deposition
What is the term for the elevation of blood urea nitrogen and creatinine levels?
Azotemia
What is the term for the derangement in capillary walls of the glomeruli that results in increased permeability to plasma proteins?
Nephrotic syndrome
What is the term for the clinical manifestations that arise from azotemia?
Uremia
What is the main cause of Acute Kidney Injury?
Acute Tubular Injury
What is the result of loss-of-function mutations in the metal ion transporter ATP7B?
Copper accumulation in the liver, brain, and eyes
What is the result of obstruction of the flow of bile?
Jaundice and bile pigment accumulation in parenchyma
What is characterized by scarring of the pelvicalyceal system and the kidney interstitium?
Chronic Pyelonephritis
What is caused by an IgE- or T cell–mediated immune reaction to a drug?
Drug-induced interstitial nephritis
What is the result of mutation in α1AT?
Alpha 1 anti-trypsin deficiency
This quiz covers various liver and bile duct disorders, including large bile duct obstruction, neonatal cholestasis, primary biliary cholangitis, and primary sclerosing cholangitis. Test your knowledge of the causes, symptoms, and characteristics of these diseases.
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