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Questions and Answers
What is the weight of a normal adult liver relative to body weight?
What is the weight of a normal adult liver relative to body weight?
Which lobe of the liver is significantly larger?
Which lobe of the liver is significantly larger?
What is the anatomical feature that separates the lobes of the liver?
What is the anatomical feature that separates the lobes of the liver?
What structure runs in the free edge of the falciform ligament?
What structure runs in the free edge of the falciform ligament?
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Which of the following vessels does NOT comprise the hilum of the liver?
Which of the following vessels does NOT comprise the hilum of the liver?
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What does the segmental subdivision of the liver depend on?
What does the segmental subdivision of the liver depend on?
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What is the color of a healthy liver?
What is the color of a healthy liver?
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Which lobe lies anteriorly between the gallbladder and the round ligament?
Which lobe lies anteriorly between the gallbladder and the round ligament?
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What percentage of the liver's blood supply is provided by the portal vein?
What percentage of the liver's blood supply is provided by the portal vein?
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Which structure is responsible for draining the secretions from the liver?
Which structure is responsible for draining the secretions from the liver?
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Which component of the liver tissue systems is primarily involved in oxygenated blood supply?
Which component of the liver tissue systems is primarily involved in oxygenated blood supply?
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What is the main source of lymph in the liver?
What is the main source of lymph in the liver?
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What structure do the intrahepatic ducts ultimately merge to form?
What structure do the intrahepatic ducts ultimately merge to form?
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What is the role of lymph vessels in the liver?
What is the role of lymph vessels in the liver?
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Which structure converges blood from the liver to join the inferior vena cava?
Which structure converges blood from the liver to join the inferior vena cava?
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Which function is primarily attributed to hepatocytes?
Which function is primarily attributed to hepatocytes?
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Which type of cell constitutes the greatest proportion of sinusoidal cells in the liver?
Which type of cell constitutes the greatest proportion of sinusoidal cells in the liver?
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What is the lifespan of hepatocytes in the liver?
What is the lifespan of hepatocytes in the liver?
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Which of the following statements about Kupffer cells is accurate?
Which of the following statements about Kupffer cells is accurate?
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What is the primary function of the valves found in lymph vessels?
What is the primary function of the valves found in lymph vessels?
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What percentage of total liver cell number do Ito cells constitute?
What percentage of total liver cell number do Ito cells constitute?
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Which component is NOT part of the stroma in the liver?
Which component is NOT part of the stroma in the liver?
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What is the primary role of biliary epithelial cells?
What is the primary role of biliary epithelial cells?
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Which portion of the hepatocyte membrane is primarily involved in absorptive and secretory functions?
Which portion of the hepatocyte membrane is primarily involved in absorptive and secretory functions?
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What composes the liver's capsule?
What composes the liver's capsule?
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What is the ratio of PIT cells to Kupffer cells?
What is the ratio of PIT cells to Kupffer cells?
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What is the significance of the perivascular connective tissue in the liver?
What is the significance of the perivascular connective tissue in the liver?
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Which of the following statements about sinusoidal cells is accurate?
Which of the following statements about sinusoidal cells is accurate?
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Which of these cell types is also known as fat-storing cells?
Which of these cell types is also known as fat-storing cells?
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What is the main structural feature of the reticular network in the liver?
What is the main structural feature of the reticular network in the liver?
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What does the portal tract in the liver contain?
What does the portal tract in the liver contain?
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Which of the following is a primary function of the hepatic lymph nodes?
Which of the following is a primary function of the hepatic lymph nodes?
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Study Notes
Liver Anatomy
- The liver is a vital organ weighing approximately 1/18 of a newborn's body weight and 1/50 of an adult's body weight.
- The liver is located in the upper right quadrant of the abdomen, protected by the rib cage.
- The liver has two lobes: the left lobe and the right lobe, separated by the falciform ligament.
- The right lobe is significantly larger than the left lobe.
Liver Topography
- The liver hilum, located on the inferior surface, contains structures like the hepatic artery, portal vein, common hepatic duct, lymph vessels, and hepatic nerve plexus.
- These structures are held together by the perivascular fibrous capsule.
Liver Structure and Histology
- The liver comprises four tissue systems:
- Intrahepatic vascular system
- Stroma
- Sinusoidal cells
- Hepatocytes
Intrahepatic Vascular System
- The hepatic artery carries oxygenated blood from the aorta, supplying approximately 25% of the liver's blood supply.
- The portal vein carries nutrient-rich blood from the gastrointestinal tract, supplying approximately 75% of the liver's blood supply.
- The hepatic vein drains blood from the liver and joins the inferior vena cava.
- The biliary system, starting with bile canaliculi, is responsible for excreting bile produced by hepatocytes.
- Lymph vessels play a vital role in draining lymph from the liver, a process which surpasses other organs in the body.
Stroma
- Stroma refers to the connective tissue in the liver and consists of:
- Capsule of the liver, a thin layer of tissue surrounding it.
- Perivascular connective tissue, a framework supporting the interlobular vessels.
- Reticular network, providing support for sinusoids and aiding in hepatocyte regeneration.
- Portal tract, containing structures like portal veins and bile ducts.
Sinusoidal Cells
- Sinusoidal cells constitute a small proportion of the liver volume but play a crucial role in its function and are categorized as:
- Endothelial cells, forming the lining of the sinusoids.
- Kupffer cells, phagocytic cells responsible for removing debris and harmful substances.
- Ito cells, involved in storing fat and producing extracellular matrix.
- PIT cells, natural killer cells that destroy tumor cells and foreign agents.
Hepatocytes
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Hepatocytes are the primary functional cells of the liver, comprising a significant portion of its volume.
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They play a vital role in metabolism, detoxification, and bile production.
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Hepatocytes have a lifespan of 150-200 days, undergoing programmed death (apoptosis).
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The liver is a complex organ with diverse functions, and its intricate structure facilitates these vital roles.
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Description
Test your knowledge on liver anatomy, topography, and histology with this quiz. Explore the structures and functions of this vital organ, including its blood supply and tissue systems. Perfect for students of anatomy and biology!