Podcast
Questions and Answers
What is the role of dendritic cells and macrophages after a vaccine is injected?
What is the role of dendritic cells and macrophages after a vaccine is injected?
- Activate the lymphocytes directly
- Take up the components of the vaccine with the help of PRRs (correct)
- Initiate the formation of memory B and T cells
- Produce antibodies to fight the pathogen
What do Antigen-presenting cells (APCs) do after getting activated?
What do Antigen-presenting cells (APCs) do after getting activated?
- Directly attack the pathogen
- Move towards lymph nodes in near areas (correct)
- Release pathogen-associated molecular patterns (PAMPs)
- Produce antibodies to fight the pathogen
What is the outcome of antigen recognition by lymphocytes?
What is the outcome of antigen recognition by lymphocytes?
- Clonal expansion of antigen-specific B and T-lymphocytes (correct)
- Activation of dendritic cells and macrophages
- Formation of memory B and T cells
- Release of pathogen-associated molecular patterns (PAMPs)
How does long-term protection against the pathogen occur?
How does long-term protection against the pathogen occur?
Which type of vaccines can induce the expression of antigens that resemble native viral epitopes more closely than standard vaccines?
Which type of vaccines can induce the expression of antigens that resemble native viral epitopes more closely than standard vaccines?
What is the major disadvantage of DNA/mRNA vaccines according to the text?
What is the major disadvantage of DNA/mRNA vaccines according to the text?
What is the advantage of DNA/mRNA vaccines in terms of antigen expression?
What is the advantage of DNA/mRNA vaccines in terms of antigen expression?
Why are DNA/mRNA vaccines considered advantageous for rapid, large-scale production?
Why are DNA/mRNA vaccines considered advantageous for rapid, large-scale production?
What limits the extent of the usage of DNA vaccines according to the text?
What limits the extent of the usage of DNA vaccines according to the text?
In what way do DNA/mRNA vaccines differ from live attenuated and killed vaccines?
In what way do DNA/mRNA vaccines differ from live attenuated and killed vaccines?
Which vaccine-preventable disease had a 100% reduction in morbidities postvaccine?
Which vaccine-preventable disease had a 100% reduction in morbidities postvaccine?
What was the estimated annual morbidity reduction percentage for measles postvaccine?
What was the estimated annual morbidity reduction percentage for measles postvaccine?
Which region experienced the world's second largest Ebola outbreak in 2018-2020?
Which region experienced the world's second largest Ebola outbreak in 2018-2020?
What was the case-fatality rate of Ebola virus disease (EVD) mentioned in the text?
What was the case-fatality rate of Ebola virus disease (EVD) mentioned in the text?
What was the outcome post vaccinations for the 2018-2020 Ebola outbreak?
What was the outcome post vaccinations for the 2018-2020 Ebola outbreak?
What is the key feature of live attenuated vaccines according to the text?
What is the key feature of live attenuated vaccines according to the text?
How are live, attenuated vaccines prepared according to the text?
How are live, attenuated vaccines prepared according to the text?
What measure was taken by the DRC's ministry of health in response to the 2018-2020 Ebola outbreak, as mentioned in the text?
What measure was taken by the DRC's ministry of health in response to the 2018-2020 Ebola outbreak, as mentioned in the text?
What was unique about the rVSV-ZEBOV-GP vaccine mentioned in the text?
What was unique about the rVSV-ZEBOV-GP vaccine mentioned in the text?
How many lives are estimated to be saved every year because of vaccines according to the text?
How many lives are estimated to be saved every year because of vaccines according to the text?
Which type of vaccine can often confer lifelong immunity with only one or two doses?
Which type of vaccine can often confer lifelong immunity with only one or two doses?
What is a drawback of inactivated whole virus vaccines in areas where people don’t have regular access to health care?
What is a drawback of inactivated whole virus vaccines in areas where people don’t have regular access to health care?
What is a disadvantage of live, attenuated vaccines for individuals with weakened immune systems?
What is a disadvantage of live, attenuated vaccines for individuals with weakened immune systems?
What is the main advantage of inactivated whole virus vaccines over live, attenuated vaccines?
What is the main advantage of inactivated whole virus vaccines over live, attenuated vaccines?
Which type of vaccine is made by purifying the bacterial exotoxin and suppressing or inactivating its toxicity?
Which type of vaccine is made by purifying the bacterial exotoxin and suppressing or inactivating its toxicity?
What is the key feature of DNA vaccines in terms of antigen expression?
What is the key feature of DNA vaccines in terms of antigen expression?
What technology involves sequencing the genome of a pathogen to specifically select a virulence factor responsible for causing disease?
What technology involves sequencing the genome of a pathogen to specifically select a virulence factor responsible for causing disease?
Which type of vaccine stimulates a weaker immune response than do live vaccines?
Which type of vaccine stimulates a weaker immune response than do live vaccines?
Why do conjugate vaccines attach polysaccharides to a stronger protein?
Why do conjugate vaccines attach polysaccharides to a stronger protein?
What is the main advantage of nucleic acid vaccines compared to traditional vaccines?
What is the main advantage of nucleic acid vaccines compared to traditional vaccines?
What is the main advantage of DNA/mRNA vaccines for rapid, large-scale production?
What is the main advantage of DNA/mRNA vaccines for rapid, large-scale production?
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