Lipid Synthesis Pathways Overview
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Questions and Answers

What is the precursor for both triacylglycerol and phospholipids?

  • CoA
  • Dihydroxyacetone phosphate
  • Phosphatidate (correct)
  • Glycerol-3-P

Which complex is used in the ER lumen for the synthesis of triacylglycerol from Phosphatidate?

  • Phospholipase complex
  • Triacylglycerol synthetase complex (correct)
  • Glycolysis complex
  • Acetyl-CoA complex

How is CDP-diacylglycerol synthesized in yeast and bacteria?

  • By linking dihydroxyacetone phosphate
  • By linking glycerol-3-P
  • By linking CTP molecules (correct)
  • By linking CoA

What drives the reaction forward during the formation of CDP-diacylglycerol?

<p>Release of pyrophosphate (A)</p> Signup and view all the answers

Which molecule links with CDP to activate diacylglycerol in mammals?

<p>Ethanolamine (B)</p> Signup and view all the answers

What is the most abundant phospholipid in animals?

<p>Phosphatidylcholine (A)</p> Signup and view all the answers

What is the precursor for cholesterol synthesis?

<p>Acetyl CoA (A)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing phosphatidylcholine from phosphatidylethanolamine?

<p>Phosphatidylethanolamine methyltransferase (A)</p> Signup and view all the answers

What is the main factor regulating cholesterol synthesis?

<p>Cholesterol levels (B)</p> Signup and view all the answers

Which molecule is used as the methyl donor in methylating the amino group of phosphatidylcholine?

<p>S-adenosylmethionine (B)</p> Signup and view all the answers

Where does the last step of cholesterol synthesis occur?

<p>Endoplasmic reticulum (ER) (B)</p> Signup and view all the answers

Which enzyme catalyzes the conversion of mevalonate to isoprene molecules in cholesterol synthesis?

<p>HMG-CoA reductase (B)</p> Signup and view all the answers

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