Lipid Metabolism Quiz
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Questions and Answers

What is the primary enzyme responsible for initiating the release of non-esterified fatty acids from adipocytes?

  • Glycerol kinase
  • Lipoprotein lipase
  • Fatty acid binding protein
  • Hormone sensitive lipase (correct)
  • What is the final product of triacylglycerol hydrolysis, apart from non-esterified fatty acids?

  • Glycogen
  • Glucose
  • Glycerol (correct)
  • Triglyceride
  • What is the role of insulin in triacylglycerol metabolism?

  • Activates lipoprotein lipase
  • Inhibits hormone sensitive lipase (correct)
  • Activates hormone sensitive lipase
  • Inhibits glycerol kinase
  • What is the primary function of fatty acid binding protein in target cells?

    <p>To bind non-esterified fatty acids</p> Signup and view all the answers

    What is the primary mechanism of non-esterified fatty acid uptake in target cells?

    <p>Passive transport</p> Signup and view all the answers

    What is the primary destination of non-esterified fatty acids released from adipocytes?

    <p>Muscle and liver</p> Signup and view all the answers

    How are non-esterified fatty acids transported in the bloodstream?

    <p>Bound to albumin</p> Signup and view all the answers

    What is the result of phosphorylation of hormone sensitive lipase?

    <p>Activation of hormone sensitive lipase</p> Signup and view all the answers

    Where are fatty acids stored primarily in the body?

    <p>Adipocytes</p> Signup and view all the answers

    What is the process of breaking down triacylglycerols to release fatty acids?

    <p>Hydrolysis</p> Signup and view all the answers

    What is the primary location of adipocytes in the body?

    <p>Abdominal cavity</p> Signup and view all the answers

    What is the function of lipoprotein-lipase in fat storage?

    <p>Breaking down chylomicron triacylglycerols</p> Signup and view all the answers

    What is the purpose of storing carbohydrates as glycogen in muscles?

    <p>For energy production during exercise</p> Signup and view all the answers

    What is the role of adipose tissue in energy production?

    <p>Releasing stored triacylglycerols for energy</p> Signup and view all the answers

    What is the metabolic activity of adipocytes?

    <p>Very active</p> Signup and view all the answers

    What is the result of triacylglycerol hydrolysis in adipose cells?

    <p>Fatty acids and glycerol entering the bloodstream</p> Signup and view all the answers

    What is the primary energy source for the body?

    <p>Carbohydrates</p> Signup and view all the answers

    What happens to glucose when energy demands exceed glycogen reserves?

    <p>Lipids are broken down into fatty acids and glycerol</p> Signup and view all the answers

    What is the function of insulin in regulating glucose levels?

    <p>It promotes the uptake of glucose into cells for energy or storage</p> Signup and view all the answers

    What is the process of synthesizing lipids from excess glucose or other substrates?

    <p>Lipogenesis</p> Signup and view all the answers

    What triggers the breakdown of lipids into fatty acids and glycerol?

    <p>Fasting or low glucose levels</p> Signup and view all the answers

    What is the function of glucagon in regulating glucose levels?

    <p>It stimulates the breakdown of glycogen and fats to increase blood glucose levels</p> Signup and view all the answers

    When does lipogenesis occur?

    <p>After high-carbohydrate meals</p> Signup and view all the answers

    What is the relationship between insulin and lipolysis?

    <p>Insulin inhibits lipolysis</p> Signup and view all the answers

    Study Notes

    Relationships Between Lipid and Carbohydrate Metabolism

    • Carbohydrates are the primary energy source for the body, broken down into glucose for immediate energy needs or stored as glycogen in the liver and muscles.
    • When energy demands exceed glycogen reserves, lipids (fats) are broken down into fatty acids and glycerol for energy production.
    • Insulin regulates glucose levels, promoting its uptake into cells for energy or storage, and inhibits lipolysis (breakdown of fats).
    • Glucagon stimulates the breakdown of glycogen and fats to increase blood glucose levels when needed.

    Lipogenesis and Lipolysis

    • Lipogenesis is the process of synthesizing lipids from excess glucose or other substrates, occurring when there's an abundance of glucose.
    • Lipolysis breaks down lipids into fatty acids and glycerol, triggered during fasting or when glucose levels are low, such as during prolonged exercise or fasting.

    Fat Absorption and Storage

    • Fatty acids are stored primarily in adipocytes as triacylglycerol.
    • Triacylglycerol must be hydrolyzed to release the fatty acids.
    • Adipocytes are found mostly in the abdominal cavity and subcutaneous tissue.
    • Adipocytes are metabolically very active, with stored triacylglycerol constantly hydrolyzed and resynthesized.

    Triacylglycerol Storage and Mobilization

    • Adipose tissue releases stored triacylglycerols as needed for energy, with fatty acids and glycerol entering the bloodstream for cellular energy production.
    • Non-esterified fatty acid release from adipocytes is initiated by the action of hormone-sensitive lipase (HSL).
    • HSL is activated by epinephrine, norepinephrine, ACTH, and glucagon, and inhibited by insulin.
    • Glycerol metabolism refers to the biochemical processes involved in the breakdown and utilization of glycerol, a three-carbon alcohol.
    • Glycerol can be derived from various sources, such as triglycerides in dietary fats, adipose tissue lipolysis, or glycerol-containing compounds.

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