Podcast
Questions and Answers
What triggers the mobilization and degradation of TAG in adipocytes?
What triggers the mobilization and degradation of TAG in adipocytes?
- Phosphatidic acid
- Hormone sensitive lipase (correct)
- Insulin
- Glycerol kinase
What are the precursors for the biosynthesis of TAG and PL?
What are the precursors for the biosynthesis of TAG and PL?
- Hormones insulin and glucagon
- Glycerol-3-PO4 and fatty acyl CoA (correct)
- Dihydroxy acetone PO4 and glycerol
- Glycerol and phosphatidic acid
Where does the breakdown product of TAG get taken up when energy is needed?
Where does the breakdown product of TAG get taken up when energy is needed?
- Adipocytes
- Pancreas
- Skeletal muscles, kidney and liver (correct)
- Brain
In which organisms are fatty acids from the diet incorporated in TAG?
In which organisms are fatty acids from the diet incorporated in TAG?
What is the common precursor for both TAG and PL?
What is the common precursor for both TAG and PL?
What are the precursors for the biosynthesis of TAG and PL?
What are the precursors for the biosynthesis of TAG and PL?
In which organisms are fatty acids from the diet incorporated in TAG?
In which organisms are fatty acids from the diet incorporated in TAG?
What triggers the mobilization and degradation of TAG in adipocytes?
What triggers the mobilization and degradation of TAG in adipocytes?
Where does the breakdown product of TAG get taken up when energy is needed?
Where does the breakdown product of TAG get taken up when energy is needed?
What is the common precursor for both TAG and PL?
What is the common precursor for both TAG and PL?
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Study Notes
Triglyceride (TAG) Mobilization and Degradation
- Hormone-sensitive lipase (HSL) triggers the mobilization and degradation of TAG in adipocytes.
Biosynthesis of TAG and Phospholipids (PL)
- Precursors for the biosynthesis of TAG and PL are glycerol-3-phosphate and fatty acids.
- Glycerol-3-phosphate is the common precursor for both TAG and PL.
Fatty Acid Incorporation
- Fatty acids from the diet are incorporated into TAG in animals.
TAG Breakdown and Uptake
- When energy is needed, the breakdown product of TAG (fatty acids) gets taken up by the liver.
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