Lipid Metabolism: Digestion of Lipids

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18 Questions

What is the primary function of chylomicrons in the body?

To make fats soluble and deliver TAGs to tissues

How are absorbed lipids utilized by tissues?

Through multiple pathways, including oxidation, gluconeogenesis, and lipogenesis

What is the main component of the hydrophobic core of chylomicrons?

Cholesteryl ester

What is the primary site of lipid absorption?

Mucosal cells

What is the term for the presence of excess bulky, whitish, and offensive fat in stool?

Steatorrhea

What is the function of apo A and apo B-48 proteins in chylomicrons?

To facilitate lipid transport

What is a possible cause of deficiency of pancreatic lipase?

Chronic pancreatitis

What is the function of Orlistate?

Inhibit lipases to decrease fat absorption

What is the normal range of total plasma lipids?

400-700 mg/dL

What is the hydrophobic core of lipoproteins composed of?

Triacylglycerols and cholesteryl esters

What is the purpose of measuring the proportion of HDL and LDL?

To assess cardiovascular disease risk

What is the consequence of bile salt deficiency?

Decreased lipid digestion

Which lipase is the main digestive enzyme in adults?

Pancreatic lipase

What is the primary function of pancreatic lipase?

Hydrolyzing triacylglycerol at position 1 and 3

What are the components of micelles?

2-MAG, long chain FAs, phospholipids, lysophospholipids, cholesterol, fat soluble vitamins, and bile salts

Where do long chain fatty acids get esterified in intestinal epithelial cells?

To reform triacylglycerol

What is the fate of bile salts, glycerol, and short and medium chain fatty acids in the intestinal epithelial cells?

They are transported via the portal blood to the liver

What is the role of intestinal lipase?

Hydrolyzing 1-MAG glycerol + FA intracellularly

This quiz covers the digestion of lipids, including triglycerides, cholesterol, and phospholipids, and the different lipases involved in each process. Learn about the role of lingual lipase, gastric lipase, and pancreatic lipase in lipid digestion.

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