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Questions and Answers
What is the main advantage of the β-oxidation of fats compared to the oxidation of sugars?
What is the main advantage of the β-oxidation of fats compared to the oxidation of sugars?
- For every cycle of oxidation of a fatty acid, one NADH and one FADH2 are produced
- Fatty acids produce more metabolic water (correct)
- The oxidation of fats produces more energy per carbon than the oxidation of carbohydrates
- Fat yields more energy than carbohydrates because it is more oxidized
What additional enzymes are required for the β-oxidation of fatty acids with an odd number of carbons?
What additional enzymes are required for the β-oxidation of fatty acids with an odd number of carbons?
- A dehydrogenase and a reductase
- A dehydrogenase and a hydrase
- A cis-trans isomerase and a dehydrogenase (correct)
- A cis-trans isomerase and a reductase
What cofactor is involved in the conversion of methylmalonyl-CoA to succinyl-CoA?
What cofactor is involved in the conversion of methylmalonyl-CoA to succinyl-CoA?
- Thiamine pyrophosphate
- Biotin
- Vitamin B12 (correct)
- NAD
How do the cis double bonds of naturally-occurring fatty acids react with the hydratase enzyme?
How do the cis double bonds of naturally-occurring fatty acids react with the hydratase enzyme?
What is the orientation of the unsaturated fatty acids that are intermediates in the β-oxidation cycle?
What is the orientation of the unsaturated fatty acids that are intermediates in the β-oxidation cycle?
How does the yield of ATP from the oxidation of an unsaturated fatty acid compare to the yield from the oxidation of a saturated fatty acid with the same number of carbon atoms?
How does the yield of ATP from the oxidation of an unsaturated fatty acid compare to the yield from the oxidation of a saturated fatty acid with the same number of carbon atoms?
What are the products of β-oxidation of oleic acid (18:1Δ9)?
What are the products of β-oxidation of oleic acid (18:1Δ9)?
How many ATP equivalents are required for the activation of oleic acid (18:1Δ9) prior to β-oxidation?
How many ATP equivalents are required for the activation of oleic acid (18:1Δ9) prior to β-oxidation?
What is the ultimate fate of the propionyl-CoA produced during β-oxidation of odd-chain fatty acids?
What is the ultimate fate of the propionyl-CoA produced during β-oxidation of odd-chain fatty acids?
Which of the following is NOT a possible use of the acetyl-CoA produced during β-oxidation?
Which of the following is NOT a possible use of the acetyl-CoA produced during β-oxidation?
How many NAD+ are reduced during the β-oxidation of stearoyl-CoA (18:0) to form nine molecules of acetyl-CoA?
How many NAD+ are reduced during the β-oxidation of stearoyl-CoA (18:0) to form nine molecules of acetyl-CoA?
What is the correct sequence for the transport of fatty acyl groups from the cytosol to the mitochondrial matrix?
What is the correct sequence for the transport of fatty acyl groups from the cytosol to the mitochondrial matrix?
Which of the following is a product of the complete β-oxidation of oleic acid (C18:1)?
Which of the following is a product of the complete β-oxidation of oleic acid (C18:1)?
How is propionyl-CoA converted to a metabolite that can enter the TCA cycle?
How is propionyl-CoA converted to a metabolite that can enter the TCA cycle?
Which of the following is a major fate of acetyl-CoA produced from β-oxidation?
Which of the following is a major fate of acetyl-CoA produced from β-oxidation?
Which of the following statements about β-oxidation of fatty acids is true?
Which of the following statements about β-oxidation of fatty acids is true?
How many $FADH_2$ and $NADH$ molecules are produced during the complete β-oxidation of palmitic acid (C16:0)?
How many $FADH_2$ and $NADH$ molecules are produced during the complete β-oxidation of palmitic acid (C16:0)?
Which of the following statements about the energetics of β-oxidation is false?
Which of the following statements about the energetics of β-oxidation is false?
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