Lidocaine: Uses and Contraindications
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Questions and Answers

What is the principal use of lidocaine?

  • As a muscle relaxant
  • As a sedative
  • As a local and topical anesthetic (correct)
  • As an anti-inflammatory agent

Which of the following ailments is lidocaine used to relieve discomfort from?

  • Sunburn and insect bites (correct)
  • Fractures
  • Chronic pain syndromes
  • Post-surgical pain

Who developed lidocaine and in what year?

  • Bengt Lundqvist in 1943
  • Bengt Lundqvist in 1949
  • Nils Löfgren in 1943 (correct)
  • Nils Löfgren in 1949

What is a contraindication for utilizing lidocaine?

<p>Hypersensitivity to local anesthetics of the amide type (B)</p> Signup and view all the answers

What is the classification of lidocaine?

<p>Amide (D)</p> Signup and view all the answers

Which of the following indicates the potency of lidocaine relative to procaine?

<p>Potency = 2 for lidocaine (A)</p> Signup and view all the answers

Which enzyme system is involved in the metabolism of lidocaine?

<p>Microsomal fixed-function oxidases in the liver (D)</p> Signup and view all the answers

What year was lidocaine launched for use?

<p>1949 (D)</p> Signup and view all the answers

Flashcards

Lidocaine

A tertiary amine antiarrhythmic drug used for local and topical anesthesia.

Local Anesthetic

A medicine that blocks nerve signals, causing numbness in a specific area.

Topical Anesthetic

A local anesthetic applied to the skin's surface.

Amide local anesthetic

A class of local anesthetics that includes lidocaine; metabolized differently from ester-type anesthetics.

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Lidocaine Hydrochloride

The salt form of lidocaine, commonly used in injectable anesthetic solutions.

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Contraindications

Medical conditions or situations where a drug should not be used because of potential risks.

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Hypersensitivity

An excessive or abnormal immune response to a substance.

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Toxicity

The degree to which a substance is harmful or poisonous.

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Study Notes

Introduction

  • Lidocaine is a tertiary amine antiarrhythmic drug primarily used for local and topical anesthesia.
  • The first amino amide-type local anesthetic, previously amino esters, was developed by a Swedish scientist.
  • It was initially called "xylocaine" and launched in 1949.

Classification

  • Lidocaine's potency is 2 compared to procaine (procaine = 1).
  • It has a toxicity level of 2 relative to procaine.
  • Liver microsomal enzymes metabolize it.

Topical Uses

  • Lidocaine reduces discomfort and itching from ailments like sunburns, insect bites, stings, poison ivy, oak, sumac, and minor cuts/scratches.

Injectable Uses

  • Xylocaine Dental (lidocaine HCI) provides local anesthesia via nerve blocks or infiltrations for established procedures.
  • Only approaches outlined in mainstream textbooks are suggested.

Contraindications

  • Lidocaine is contraindicated for those allergic to amide-type local anesthetics.
  • It is also contraindicated for patients with Stokes-Adams syndrome, Wolff-Parkinson-White syndrome, or severe degrees of sinoatrial, atrioventricular, or intraventricular blocks.

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Description

Explore the diverse applications of Lidocaine, from its historical background to its classification and effective uses in local anesthesia. This quiz will also cover important contraindications to ensure safe usage. Test your knowledge on this essential medical topic.

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