24 Questions
What is the most common age of onset for lichen striatus?
Between 3 and 5 years
What is the gender ratio for lichen striatus?
2-3:1 (female to male)
What is a possible cause of lichen striatus according to the text?
Environmental stressors
What is the etiology of lichen striatus based on the text?
Somatic mosaicism
Which part of the body does lichen striatus most frequently affect?
Limbs
What percentage of individuals with lichen striatus have a personal or family history of atopy?
60%
What is the most common time of onset for lichen striatus outbreaks?
Spring and summer
Which virus has been detected within lesions of linear lichen planus?
Herpes virus
What is the typical presentation of lichen striatus?
Flat-topped, 1- to 3-mm, pink, tan, or hypopigmented papules in a linear configuration or Blaschkoid distribution
Where is pruritus most commonly present in cases of lichen striatus?
In 5-34% of cases
Which body locations are most commonly affected by lichen striatus?
Extremities and trunk
What type of skin changes are seen in cases of nail involvement in lichen striatus?
Longitudinal ridging, onycholysis, splitting, fraying, and loss of the nail plate
Which cells are the predominant infiltrate at the dermoepidermal junction (DEJ) in lichen striatus?
CD8 cells
What is the mean duration of lichen striatus?
~6-12 months
What is the recommended first-line topical treatment for symptomatic pruritus in lichen striatus?
Topical steroids
What percentage of lichen striatus cases show postinflammatory hypopigmentation?
50%
Which cells are decreased overall in lichen striatus?
Langerhans cells
What is the first-line topical treatment for symptomatic pruritus in lichen striatus?
Low to mid-potency topical steroids
Which medication can be used as an effective alternative for lichen striatus if there is facial involvement or disease refractory to topical corticosteroids?
Topical calcineurin inhibitors
What may be helpful in cases of more generalized itch or in cases of sleep disruption in lichen striatus?
Oral antihistamines
What is a possible treatment combination for nail involvement in lichen striatus, as mentioned in the text?
Topical corticosteroids and calcineurin inhibitors combined with intralesional corticosteroids
What is a common histologic finding in cases of lichen striatus?
Mild spongiosis with a lichenoid tissue reaction
Which skin condition can mimic the histologic features of lichen striatus?
Lichen planus
In clinical practice, which type of skin changes are rarely seen in cases of lichen striatus?
Vesicles
Explore the characteristics and prevalence of lichen striatus, a rare linear dermatosis most commonly affecting individuals under the age of 18. Understand its self-limited nature and its occurrence on the limbs, particularly in females.
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