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Questions and Answers
What was the mean age of the children treated with levofloxacin?
4.41 years
What percentage of microbiological test results turned negative after levofloxacin treatment?
39.29%
How many adverse events occurred during the treatment period?
57
What percentage of courses showed a decrease in inflammatory markers after levofloxacin treatment?
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What type of study was conducted to assess the use of levofloxacin in children?
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What is the implication of the study's finding that only a small percentage of adverse events were possibly related to levofloxacin?
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How does the study's outcome relate to the growing concern about multidrug-resistant bacteria?
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What can be inferred about the efficacy of levofloxacin in treating serious infections in children based on the study's results?
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How do the study's findings on adverse events compares to expectations?
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What is the significance of the study's results in the context of pediatric treatment options?
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Study Notes
Levofloxacin Use in Children with Serious Infections
- Levofloxacin shows promising effectiveness in treating serious infections in children, particularly for multidrug-resistant bacteria.
Study Details
- A retrospective observational study of patients was conducted.
- 25 patients were treated with 28 courses of levofloxacin.
- The mean age of the children treated with levofloxacin was 4.41 years.
Treatment Outcomes
- 39.29% of courses (11 out of 28) showed conversion of pathogenic microbiological test results to negative after levofloxacin treatment.
- 64.29% of courses (18 out of 28) showed a decrease in inflammatory markers, such as white blood cell or C-reactive protein counts.
Adverse Events
- A total of 57 adverse events occurred during the treatment period.
- 21 adverse events were possibly related to levofloxacin, but none were highly probably related to levofloxacin.
Levofloxacin Use in Children with Serious Infections
- Levofloxacin shows promising effectiveness in treating serious infections in children, particularly for multidrug-resistant bacteria.
Study Details
- A retrospective observational study of patients was conducted.
- 25 patients were treated with 28 courses of levofloxacin.
- The mean age of the children treated with levofloxacin was 4.41 years.
Treatment Outcomes
- 39.29% of courses (11 out of 28) showed conversion of pathogenic microbiological test results to negative after levofloxacin treatment.
- 64.29% of courses (18 out of 28) showed a decrease in inflammatory markers, such as white blood cell or C-reactive protein counts.
Adverse Events
- A total of 57 adverse events occurred during the treatment period.
- 21 adverse events were possibly related to levofloxacin, but none were highly probably related to levofloxacin.
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Description
This quiz assesses your understanding of the effectiveness and safety of levofloxacin therapy in treating serious infections in children, including its use against multidrug-resistant bacteria.
