Levofloxacin Flashcards
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Questions and Answers

What classification does levofloxacin belong to?

  • Antipyretics
  • Analgesics
  • Antidepressants
  • Anti-infectives (correct)
  • What are the indications for using levofloxacin?

    Urinary tract infections, respiratory tract infections, skin infections, and post-exposure prophylaxis of inhalational anthrax.

    What is a contraindication of levofloxacin?

    Hypersensitivity.

    Which of the following are side effects of levofloxacin? (Select all that apply)

    <p>Agitation</p> Signup and view all the answers

    What are some adverse reactions associated with levofloxacin?

    <p>Elevated intracranial pressure, seizures, torsade de pointes, hepatotoxicity, and Stevens-Johnson syndrome.</p> Signup and view all the answers

    The onset time for levofloxacin when taken PO (by mouth) is ______.

    <p>1-2 hours</p> Signup and view all the answers

    What is the standard dosage of levofloxacin for adults?

    <p>250-750 mg every 24 hours.</p> Signup and view all the answers

    Study Notes

    Levofloxacin (Levaquin) Overview

    • Classification: Therapeutic anti-infectives used to treat a variety of infections.

    Indications

    • Effective against urinary tract infections, including cystitis, pyelonephritis, and prostatitis.
    • Treats respiratory tract infections such as acute sinusitis, acute exacerbations of chronic bronchitis, community-acquired pneumonia, and nosocomial pneumonia.
    • Used for uncomplicated and complicated skin and skin structure infections.
    • Administered as post-exposure prophylaxis for inhalational anthrax.

    Contraindications

    • Not recommended for individuals with hypersensitivity to levofloxacin or related drugs due to potential cross-sensitivity within the class.

    Side Effects

    • Common side effects may include:
      • Neurological: agitation, anxiety, confusion, depression, dizziness, drowsiness, hallucinations, insomnia, nightmares, paranoia, tremor.
      • Gastrointestinal: abdominal pain, diarrhea, nausea.
      • Dermatological: rash, photosensitivity.
      • Other: headache, phlebitis at IV site.

    Adverse Reactions

    • Serious adverse reactions can include:
      • Elevated intracranial pressure.
      • Seizures.
      • Torsades de pointes (a type of abnormal heart rhythm).
      • Pseudomembranous colitis (inflammation of the colon).
      • Hepatotoxicity (liver damage).
      • Stevens-Johnson syndrome (serious skin reaction).

    Pharmacokinetics

    • Routes of administration and effects:
      • Oral (PO): Rapid onset within 1-2 hours, peak effect at 24 hours.
      • Intravenous (IV): Rapid onset by the end of infusion, peak effect at 24 hours.

    Dosage

    • Dosage for adults:
      • Administered orally or intravenously, typically ranging from 250-750 mg every 24 hours, depending on the specific infection being treated.

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    Description

    Test your knowledge on Levofloxacin (Levaquin) with these flashcards. This quiz covers key therapeutic classifications and indications, including various infections it treats. Perfect for medical students and pharmacy learners.

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