Lehninger Biochemistry Chapter 2 & 3

Chapter Organization and Resources

• The textbook, Lehninger Principles of Biochemistry, Sixth Edition, includes various media resources on the Instructor's CD-ROM and website (www.courses.bfwpub.com/lehninger6e).
• It contains mechanism animations (12 total), technique animations (10 total), living graphs (15 total), and molecular structure tutorials (9 total).
• Mechanism animations detail specific biochemical reactions.
• Technique animations demonstrate research methods.
• Living graphs allow manipulation of parameters and visualization of results.
• Molecular structure tutorials support comprehension using 3D molecular models.
• New animations will be added throughout the edition's lifespan.

Specific Chapter Content

• Chapter 2: Water
• Chapter 3: Amino Acids, Peptides, and Proteins (including molecular structure tutorials on protein architecture—amino acids, sequence and primary structure, α helix, β sheet, turn, introduction to tertiary structure, tertiary structure of fibrous proteins, tertiary structure of small globular proteins, tertiary structure of large globular proteins, and quaternary structure)
• Chapter 5: Protein Function (includes molecular structure tutorials on oxygen-binding proteins—Myoglobin, hemoglobin, and hemoglobin susceptibility to allosteric regulation, and MHC molecules; Living Graphs on protein-ligand interactions, binding curve for myoglobin, cooperative ligand binding, and Hill equation)
• Chapter 6: Enzymes (containing Living Graphs related to the Michaelis-Menten equation, competitive inhibitors, uncompetitive inhibitors, mixed inhibitors, and Lineweaver-Burk equation; and a mechanism animation for chymotrypsin)
• Chapter 8: Nucleotides and Nucleic Acids (includes a molecular structure tutorial on building blocks of nucleic acids)
• Chapter 9: DNA-Based Information Technologies (includes technique animations for plasmid cloning, reporter constructs, and polymerase chain reaction)
• Chapter 11: Biological Membranes and Transport (includes living graphs concerning free-energy change for transport and free-energy change for transport of ions; and a molecular structure tutorial on bacteriorhodopsin)
• Chapter 12: Biosignaling (includes a molecular structure tutorial on trimeric G proteins)
• Chapter 13: Bioenergetics and Biochemical Reaction Types (includes living graphs on free-energy change and free-energy of hydrolysis of ATP)
• Chapter 14: Glycolysis, Gluconeogenesis, and the Pentose Phosphate Pathway (includes mechanism animations for phosphohexose isomerase, alcohol dehydrogenase, and thiamine pyrophosphate mechanisms)
• Chapter 16: The Citric Acid Cycle (includes a mechanism animation for citrate synthase)
• Chapter 17: Fatty Acid Catabolism (includes a mechanism animation for fatty acyl-CoA synthetase)
• Chapter 18: Amino Acid Oxidation and the Production of Urea (includes mechanism animations for pyridoxal phosphate reactions)
• Chapter 19: Oxidative Phosphorylation and Photophosphorylation (includes a living graph for free-energy change for transport of an ion)
• Chapter 20: Carbohydrate Biosynthesis in Plants and Bacteria (includes a mechanism animation for Rubisco)
• Chapter 22: Biosynthesis of Amino Acids, Nucleotides, and Related Molecules (includes mechanism animations for tryptophan synthase and thymidylate synthase)
• Chapter 24: Genes and Chromosomes (includes an animation on three-dimensional packaging of nuclear chromosomes)
• Chapter 25: DNA Metabolism (includes molecular structure tutorials on restriction endonucleases, animation on nucleotide polymerization by DNA polymerase, and DNA synthesis)
• Chapter 26: RNA Metabolism (includes an animation on mRNA splicing and a molecular structure tutorial on hammerhead ribozyme; and an animation on the life cycle of an mRNA)
• Chapter 28: Regulation of Gene Expression (includes a molecular structure tutorial on the lac repressor)
• Techniques: Immunoblotting, SDS Gel Electrophoresis, Dideoxy Sequencing of DNA.

Explore key concepts from Chapters 2 and 3 of the Lehninger Principles of Biochemistry, focusing on water's properties and the structure of amino acids and proteins. This quiz assesses your understanding of biochemical reactions, molecular structures, and related techniques using interactive animations and tutorials.