Learning Outcomes 2 - Dr. Amani Mahbub Explanation on Inflammation
23 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main cause of redness and heat during inflammation?

  • Altered vascular flow (correct)
  • Increased hydrostatic pressure
  • Increased vascular permeability
  • Accumulation of neutrophils
  • Which process allows plasma proteins and leukocytes to enter sites of infection or tissue damage?

  • Endothelial injury
  • Stasis of blood flow
  • Vasodilation
  • Increased vascular permeability (correct)
  • What type of fluid accumulation results in edema with high protein content and cells?

  • Hydrostatic prostatie
  • Histamine-induced fluid
  • Exudate (correct)
  • Transudate
  • What is the main mechanism behind the prolonged response phase of fluid loss and permeability during inflammation?

    <p>Direct endothelial injury</p> Signup and view all the answers

    Which step involves migration of leukocytes across the endothelium during inflammation?

    <p>Transmigration</p> Signup and view all the answers

    What family of proteins mediates the process of leukocyte rolling on the endothelial surface?

    <p>Selectin family</p> Signup and view all the answers

    Which proteins interact with leukocyte integrins to mediate leukocyte adhesion to endothelial cells?

    <p>Igs superfamily</p> Signup and view all the answers

    What is the main site of leukocyte accumulation before transmigration across the endothelium?

    <p>Lumen</p> Signup and view all the answers

    What is the primary function of extravasation during inflammation?

    <p>Delivery of leukocytes to the site of injury</p> Signup and view all the answers

    Which event triggers the movement of transmigrated leukocytes toward a chemotactic agent?

    <p>Chemotactic response</p> Signup and view all the answers

    What are the cardinal signs of inflammation according to Celsus?

    <p>Heat, redness, edema, pain</p> Signup and view all the answers

    Which cells recognize microbes and damaged cells and trigger the vascular and cellular reactions of inflammation?

    <p>Macrophages</p> Signup and view all the answers

    What are the four major components of acute inflammation?

    <p>Vascular changes, cellular events, mediators, microvascular changes</p> Signup and view all the answers

    What is the earliest manifestation of acute inflammation in terms of vascular changes?

    <p>Vasodilation</p> Signup and view all the answers

    Which event leads to the main local manifestation of erythema and warmth in acute inflammation?

    <p>Vascular dilation</p> Signup and view all the answers

    Who first listed the cardinal signs of inflammation during the first century AD?

    <p>Celsus</p> Signup and view all the answers

    Which component triggers vasodilation in the event of inflammation?

    <p>Histamine</p> Signup and view all the answers

    What is the unique feature of the inflammatory process?

    <p>Reaction of blood vessels leading to fluid and leukocyte accumulation in extravascular tissues</p> Signup and view all the answers

    What does inflammation aim to eliminate?

    <p>Both the initial cause of cell injury and the resulting necrotic cells and tissues</p> Signup and view all the answers

    What is the primary goal of inflammation?

    <p>To initiate the repair process</p> Signup and view all the answers

    What does the suffix '-itis' after an organ denote?

    <p>Inflammation in that site</p> Signup and view all the answers

    How does inflammation respond to vascularized tissues?

    <p>It delivers leukocytes and molecules of host defense to those tissues</p> Signup and view all the answers

    Why is inflammation described as a protective response?

    <p>Because it is intended to eliminate the initial cause of cell injury and necrotic cells</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser