Gray's Anatomy Chapter 65 - Large Intestine

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What embryological structure gives rise to the large intestine?

  • The distal midgut, entire hindgut, and the anal pit. (correct)
  • The foregut and midgut exclusively
  • The entire midgut
  • The primitive gut tube exclusively

How do the taeniae coli contribute to the macroscopic structure of the colon?

  • By providing attachment points for omental appendices only.
  • By creating haustra visible on plain radiographs. (correct)
  • By uniformly increasing the diameter of the colon.
  • By forming complete, circumferential muscular layers around the colon.

What structural features differentiate the large intestine from the small intestine?

  • Larger calibre, haustra, omental appendices, and concentration of longitudinal muscle into taeniae coli. (correct)
  • Presence of villi, greater length, and absence of taeniae coli.
  • Smaller calibre, fixed position, and continuous outer longitudinal muscle layer.
  • Presence of Peyer's patches, villi, and a mobile mesentery.

How does the taeniae coli arrangement differ between the colon and the rectum?

<p>The taeniae coli merge to form a complete longitudinal muscle layer in the rectum. (C)</p> Signup and view all the answers

During a colonoscopy, what visual feature helps the clinician identify the caecum?

<p>A characteristic 'trefoil' pattern where the taeniae coli converge. (D)</p> Signup and view all the answers

What is the clinical significance of different wall thicknesses along the colon during endoscopic procedures?

<p>The caecum and ascending colon have the thinnest walls, increasing perforation risk during therapeutic interventions. (A)</p> Signup and view all the answers

How does the tortuosity of the sigmoid colon affect endoscopic visualization?

<p>Shorter lengths of the sigmoid colon may be visible during endoscopy compared to elsewhere in the colon. (D)</p> Signup and view all the answers

What is the function of the spiral valves of Houston?

<p>Act as landmarks for planning surgery. (B)</p> Signup and view all the answers

What is the radiological importance of the transverse colon’s mesentery regarding its position in the abdomen?

<p>It allows considerable mobility, leading to a variable position within the upper abdomen. (C)</p> Signup and view all the answers

What is the clinical significance of the marginal artery (of Drummond) in cases of vascular occlusion?

<p>It can massively dilate to become a critical collateral pathway, maintaining colonic viability. (D)</p> Signup and view all the answers

Which segment of the large intestine is most susceptible to ischemia and why?

<p>The left colic flexure and proximal descending colon, farthest from major collateral arterial supplies. (C)</p> Signup and view all the answers

What is the lymphatic drainage pattern of the large intestine, and what clinical implications does this have?

<p>It follows the course of the arteries, important for surgical planning in cancer resections. (B)</p> Signup and view all the answers

How does the surgical approach to a cancer differ based on its location within the large intestine?

<p>Right-sided cancers require lymph node retrieval different from left-sided cancers due to mesenteric node size variations.. (A)</p> Signup and view all the answers

What is the basis of the arterial supply of the caecum and appendix, and how does this affect the risk of ischemia or infarction in appendicitis?

<p>They are supplied by end arteries, increasing the risk of ischemia and infarction if blood flow is compromised. (B)</p> Signup and view all the answers

How do the clinical symptoms of acute appendicitis correlate with the innervation of the appendix and surrounding structures?

<p>Initial vague periumbilical pain followed by localization to the right lower quadrant due to sequential visceral and somatic nerve involvement. (B)</p> Signup and view all the answers

What is the potential clinical impact of surgical removal of the appendix.

<p>Disturb gut ability to repopulate microbes. (D)</p> Signup and view all the answers

Where may a retrocaecal appendix be found, and what is its relationship to the iliacus and psoas major muscles?

<p>Behind the caecum and anterior to the iliacus and psoas major muscles. (C)</p> Signup and view all the answers

How does the blood supply to the ascending colon relate to the right kidney and right ureter?

<p>The right colic artery anterior to the right kidney and the ureter. (B)</p> Signup and view all the answers

What artery travels across the anterior surfaces of the psoas major muscle and gonadal vessels before supplying the ascending colon?

<p>Right colic artery (B)</p> Signup and view all the answers

How does the venous drainage of the midgut derivatives differ from that of the hindgut derivatives?

<p>Midgut derivatives drain into the superior mesenteric vein, while hindgut derivatives drain into the inferior mesenteric vein. (C)</p> Signup and view all the answers

When evaluating a CT scan, what is the significance of identifying the inferior mesenteric vein in relation to the duodenum?

<p>Indication of blood vessels that run by the duodenum. (C)</p> Signup and view all the answers

What anatomical relationship complicates surgical access on the surface of the structures?

<p>The vessels are more challenging than anticipated, leading to more vessel tears during procedures. (B)</p> Signup and view all the answers

What may be determined if the surgeon ligates the inferior mesenteric and superior mesenteric vessels?

<p>Ischemic bowel condition develops. (D)</p> Signup and view all the answers

Where does the inferior mesenteric vein typically drain, and what structures does it pass near in its course?

<p>Drains into the splenic vein, passing and crossing over multiple structures. (D)</p> Signup and view all the answers

What happens to the thickness of the inner circular muscle layer of the sigmoid as it nears the anal structure?

<p>The vessel layer gets thicker and is more difficult to manage. (D)</p> Signup and view all the answers

In relation to surgical removal, what must occur to give the best results and removal after mesorectum damage?

<p>Complete excision of the mesorectum, within its defined fascia, is required for good outcomes. (A)</p> Signup and view all the answers

During a surgical resection to remove the colorectal cancers, one issue that can come about is what?

<p>Recurrence will likely present after an incident such as the formation from new tumour cells. (D)</p> Signup and view all the answers

Between each sigmoid colon junction is an area filled with what structure?

<p>Filled by long mesocolon. (C)</p> Signup and view all the answers

What results from the sigmoid mesocolon and sigmoid colon are not within range of human measurements?

<p>Sigmoid volvulus is more likely, increasing the risk of bowel obstruction. (B)</p> Signup and view all the answers

Which types of bacteria can have increased likelihood to form with sigmoid diverticula?

<p>Intestinal and bacterial types often contribute to bowel disruption. (D)</p> Signup and view all the answers

The meso-rectum is known to consists of what specific function for support in structure that could impact the colon?

<p>Nodes and more specific fat to be protected. (B)</p> Signup and view all the answers

How does the arrangement of muscle layers in the rectum differ from that in the colon?

<p>The rectum has a complete longitudinal muscle layer, whereas the colon's longitudinal muscle is concentrated in taeniae coli. (D)</p> Signup and view all the answers

What is the significance of the omental appendices' distribution along the large intestine?

<p>Their presence or absence helps differentiate between different segments of the large intestine during surgery or imaging. (D)</p> Signup and view all the answers

How does the rotation of the taeniae coli in the transverse colon impact surgical planning compared to other segments?

<p>It necessitates altering surgical approaches because the typical taeniae coli positions are altered. (D)</p> Signup and view all the answers

What clinical implication arises from the thinner wall of the caecum and ascending colon during endoscopic procedures?

<p>The risk of perforation is higher during therapeutic interventions. (D)</p> Signup and view all the answers

How do the distinct endoscopic appearances of the caecum, ascending colon, transverse colon, and sigmoid colon aid in diagnosis?

<p>They help in determining the exact location within the large intestine and detecting abnormalities specific to each region. (D)</p> Signup and view all the answers

In what way might the spiral arrangement of mucosa near the appendix orifice be clinically misleading?

<p>May be mistaken for a polyp or other lesion, leading to unnecessary biopsy. (B)</p> Signup and view all the answers

What is the clinical relevance of the ileocaecal valve's configuration?

<p>Its precise form affects the risk of ileal intussusception into the colon. (D)</p> Signup and view all the answers

How does the variable length of the sigmoid mesentery influence the selection of surgical techniques to address sigmoid volvulus?

<p>A long mesentery increases the risk of post-operative adhesive bowel obstruction. (C)</p> Signup and view all the answers

How does the limited arterial supply to the distal transverse colon near the left colic flexure relate to the severity of ischemic colitis?

<p>Increases vulnerability to ischemia. (A)</p> Signup and view all the answers

Which aspect of the midgut-hindgut arterial anastomosis has the greatest effect on ischemia risk?

<p>Variations in the diameter and completeness of the marginal artery. (B)</p> Signup and view all the answers

How does the presence of an accessory middle colic artery impact surgical planning for colon resections?

<p>It requires careful identification and preservation to maintain adequate blood supply to remaining segments. (A)</p> Signup and view all the answers

What anatomical factor most significantly explains the increased risk of gangrenous perforation in acute appendicitis compared to other intestinal inflammations?

<p>The appendix is an end artery. (A)</p> Signup and view all the answers

What is the most likely clinical outcome from damage to the hypogastric plexus?

<p>It would be the interruption of function of bowel and bladder. (A)</p> Signup and view all the answers

How would the surgeon know if they were to damage a structure or the sacral plexus during surgery?

<p>Nerve damage would interrupt multiple visceral outputs, but bowel, bladder, and sexual function would result. (D)</p> Signup and view all the answers

In which scenario would an ileoscopy be required?

<p>Examine how the endoscopically cannulated terminal ileum works. (B)</p> Signup and view all the answers

What structures do the terminal branches supply blood to along the walls of the rectum?

<p>Supply the rectal mucosa and submucosa, with some perforating through the muscle. (A)</p> Signup and view all the answers

Which feature does the internal anal sphincter lack?

<p>Has no voluntary control by individuals. (C)</p> Signup and view all the answers

Which of these aspects does a rectal examination impact?

<p>Can allow for direct palpation, visualization during analysis and the level may be determined directly. (B)</p> Signup and view all the answers

When referring to cancer-based removals, which set of circumstances lead to a strong removal and what action is completed?

<p>Nodes along vessels have to be removed within the highest regions to ensure lymph has been removed (C)</p> Signup and view all the answers

A mass on the wall of the caecum was discovered. How would this particular area need care?

<p>It is at the highest risk of distension if colonic pressure elevates. (B)</p> Signup and view all the answers

During embryogenesis, what forms of the hindgut would come to contribute to the rectum section of the colon?

<p>The external part near the pit and sigmoid sections. (A)</p> Signup and view all the answers

If a patient's ascending colon is firmly adhered to the retroperitoneum, yet the transverse colon is freely mobile within the upper abdomen, which mesentery arrangement is most likely?

<p>The ascending colon lacks a mesentery, while the transverse colon is suspended by a mesocolon. (C)</p> Signup and view all the answers

Which statement best explains the taeniae coli arrangement in the transverse colon compared to the ascending and descending colon?

<p>The taeniae coli are rotated due to the transverse colon's dependent position, affecting their relative anterior, posterior, and lateral orientations. (B)</p> Signup and view all the answers

A gastroenterologist is performing a colonoscopy. What visual cue would indicate the distal end of the cecum is being approached?

<p>A 'trefoil' pattern of the confluence of the taeniae coli. (B)</p> Signup and view all the answers

A surgical team is planning a colectomy involving the transverse colon. How does the arterial supply influence potential anastomosis sites relative to the midgut-hindgut boundary?

<p>The dual, but often variably dominant blood supply impacts selection with ischemia risk if circulation is poor. (A)</p> Signup and view all the answers

In a patient presenting with suspected acute appendicitis, where does the pain typically localize after somatic nociceptors are stimulated, and why?

<p>Localized to the right iliac fossa due to stimulation of somatic nociceptors. (A)</p> Signup and view all the answers

A previously healthy patient undergoes a colonoscopy. The scope is advanced beyond the sigmoid colon. What identifies this?

<p>Thicker and shorter haustra, producing a more circular lumen cross-section. (A)</p> Signup and view all the answers

What anatomical variant increases the risk of a sigmoid volvulus and why?

<p>A longer mesosigmoid, creating more points that can get trapped. (C)</p> Signup and view all the answers

Why can appendicitis be difficult to detect in the elderly?

<p>Inflammatory suspicion is low, causing higher misdiagnosis. (B)</p> Signup and view all the answers

What type of muscular contraction is associated with segmental mixing?

<p>Non-Propagating contraction (C)</p> Signup and view all the answers

What is the anatomical distinction at the anal sphincters that help determine anal cancer?

<p>The terminal end at the mucosa and squamous (C)</p> Signup and view all the answers

What is the functional impact of interstitial cells of Cajal (ICC) within the enteric nervous system of the large intestine?

<p>Provide intrinsic pacemaker activity modulated by external nerves for rhythmic contractions. (B)</p> Signup and view all the answers

How does the lymphatic drainage pattern of the distal transverse colon or left colic flexure impact surgical decision-making in cancer cases?

<p>May spread with middle or superior, impacting surgical decision. (D)</p> Signup and view all the answers

What anatomical feature is commonly found within the anal sinuses and, when occluded, can lead to perianal abscesses?

<p>Anal glands with stratfied ducts (B)</p> Signup and view all the answers

What structural modification enhances distensibility in distal rectum?

<p>Submucosal vessels and adipose tissue separate from structure. (B)</p> Signup and view all the answers

While palpating what location is the ischial spine palpated?

<p>Proximal anal along lumen. (D)</p> Signup and view all the answers

A patient presents with colicky pain but an otherwise clear scan. However, testing shows blockage. Which type of muscular contraction contributes?

<p>Propagating (B)</p> Signup and view all the answers

What vessel is tented due to traction of the ascending colon?

<p>Ileocolic when approaching ileac spine (B)</p> Signup and view all the answers

Visceral nerves and location where cell bodies pass through?

<p>M1 and M2 and ventral root L3 and L4 (C)</p> Signup and view all the answers

Anorectal junction passes through what

<p>Pubo-analis of levator (E)</p> Signup and view all the answers

The taeniae coli transition to smooth muscle and what point

<p>Distal sigmoid. (C)</p> Signup and view all the answers

How does a surgical team make a decision with vessel ligation?

<p>They ligate with care of the colic artery (A)</p> Signup and view all the answers

With the superior mesenteric, what becomes part of anastomosis?

<p>Middle vessels (A)</p> Signup and view all the answers

The mucosa will have a fold but one exception

<p>Is the rectos. (B)</p> Signup and view all the answers

With diverticula, where do they come commonly in parallel?

<p>2 anti with enter (B)</p> Signup and view all the answers

Agenesis will rarely impact?

<p>Colon region. (A)</p> Signup and view all the answers

How is levator ani damaged?

<p>Traumatic (D)</p> Signup and view all the answers

Why does the rectum change to a posterior direction?

<p>Pubo anterior makes. (A)</p> Signup and view all the answers

The large intestine receives both sympathetic and parasympathetic nerve supply.

<p>True (A)</p> Signup and view all the answers

Omental appendices are most numerous on the surface of the caecum.

<p>False (B)</p> Signup and view all the answers

Taeniae coli broaden out in the distal third of the sigmoid colon where they merge to form a complete longitudinal muscle layer around the rectum.

<p>True (A)</p> Signup and view all the answers

Haustra represent sites where the submucosa completely spans the lumen forming a circumferential ring.

<p>False (B)</p> Signup and view all the answers

In the caecum, the taeniae coli converge to form a 'quatrefoil' pattern on the caecal wall.

<p>False (B)</p> Signup and view all the answers

The ileal orifice at the distal caecum can be cannulated endoscopically to examine the terminal ileum.

<p>True (A)</p> Signup and view all the answers

The volume data sets produced by multislice CT scans cannot generate virtual colonoscopic mucosal images.

<p>False (B)</p> Signup and view all the answers

The marginal artery is formed by branches arising from the ileocolic, middle colic, left colic, and the sigmoidal arteries.

<p>False (B)</p> Signup and view all the answers

Occlusion of the common iliac arteries can result in dilation of the marginal and inferior mesenteric arteries which become an important collateral supply to both the lower limbs and to the colon.

<p>True (A)</p> Signup and view all the answers

Most of the lymphatic drainage of the distal transverse colon is directed to superior mesenteric nodes.

<p>True (A)</p> Signup and view all the answers

The omental taeniae are often hidden by the peritoneal reflection on the colonic wall of the descending colon.

<p>False (B)</p> Signup and view all the answers

Anal glands typically demonstrate simple organization with single ducts lined with only glandular cells to best produce mucin.

<p>False (B)</p> Signup and view all the answers

It is considered normal for the anal canal to be roughly 10cm in length on the anterior side.

<p>False (B)</p> Signup and view all the answers

Sympathetic stimulation is important to colonic propulsions.

<p>False (B)</p> Signup and view all the answers

The presence of a local muscle thickening at th base of the ileal papilla is considered physiological, and to be related to an anatomical sphincter.

<p>True (A)</p> Signup and view all the answers

Though appendices can have various distal positions, retrocaecal or retrocolic formations are relatively rare.

<p>False (B)</p> Signup and view all the answers

The vermiform appendix has roughly the same tissue layer structure as the rest of the colon, though its structure may be simplified.

<p>True (A)</p> Signup and view all the answers

Retrograde passage of bacteria from the anal canal to the valve in the appendix is a cause of appendicitis

<p>False (B)</p> Signup and view all the answers

Appendicitis' pain is mostly a sharp sensation that comes from the somatic nocireceptors.

<p>False (B)</p> Signup and view all the answers

Anal cushions don't contain blood vessels.

<p>False (B)</p> Signup and view all the answers

Flashcards

Large Intestine Overview

The large intestine extends from the ileocaecal junction to the anus, differing from the small intestine as it has a greater calibre and is more fixed in position

Taeniae Coli

The taeniae coli are three longitudinal bands of smooth muscle that are concentrated in the colon. They broaden out in the distal part of the sigmoid colon and gradually merge to form a complete longitudinal muscle layer around the rectum.

Omental Appendices

Small, fatty projections/pouches of peritoneum that project from the external surface of the colon and are supplied by blood vessels that perforate the wall.

Haustra

Pouches in the colon wall created by infolding of the mucosa and submucosa which never form a complete circumferential ring.

Signup and view all the flashcards

Arterial Supply to the Midgut-derived Colon

The caecum, ascending colon, and proximal two-thirds of the transverse colon are supplied by branches from the superior mesenteric artery: ileocolic, right colic and middle colic arteries.

Signup and view all the flashcards

Arterial Supply to the Hindgut-derived Colon

The distal third of the transverse colon, descending and sigmoid colon, rectum and proximal anal canal are supplied predominantly from the inferior mesenteric artery via the left colic, sigmoid and superior rectal arteries

Signup and view all the flashcards

Marginal Artery (of Drummond)

Is a vessel formed by branches arising from the ileocolic, right colic, middle colic and left colic arteries, running in the mesentery along the inner margin of the descending colon.

Signup and view all the flashcards

Ileocaecal Junction

The area where the terminal ileum joins the large intestine at the junction of the caecum and colon.

Signup and view all the flashcards

Appendix

A narrow, blind-ending tube that joins the posteromedial wall of the caecum

Signup and view all the flashcards

Appendix Position

The major positions of the appendix are retrocaecal, subcaecal, pre-ileal or pelvic

Signup and view all the flashcards

Meso-appendix

A triangular mesentery running between the terminal ileum and appendix, containing a variable amount of fat.

Signup and view all the flashcards

Ascending Colon

Ascends from the ileocaecal junction to the right colic flexure, separated posteriorly by loose connective tissue from the iliac fascia.

Signup and view all the flashcards

Right Colic Artery

A vessel that is variable in its anatomy; either a common trunk with the middle colic artery, originates directly from the superior mesenteric artery or from the ileocolic artery

Signup and view all the flashcards

Right Colic Flexure

Connects the ascending and transverse colons; variable in position and less acute than the left colic flexure.

Signup and view all the flashcards

Transverse Colon

Variable in length, it is suspended by the transverse mesocolon and extends between the right and left colic flexures.

Signup and view all the flashcards

Middle Colic Artery

Originates from the superior mesenteric artery, passing anteriorly within the transverse mesocolon.

Signup and view all the flashcards

Left Colic Flexure

Marks the junction between transverse and descending colons, lying in the left hypochondriac region anterior to the tail of pancreas and the left kidney.

Signup and view all the flashcards

Descending Colon

Descends from the left colic flexure to the iliac crest; retroperitoneal and more deeply placed than the ascending colon.

Signup and view all the flashcards

Sigmoid Arteries

From 2-5 arteries that descend obliquely in the sigmoid mesocolon to supply the descending and sigmoid colon.

Signup and view all the flashcards

Sigmoid Colon

The sigmoid colon is suspended from the pelvic walls by the sigmoid mesocolon. It runs from the greater pelvis to the beginning of the Rectum.

Signup and view all the flashcards

Superior Rectal Artery

Arises from the inferior mesenteric artery and supplies the upper two-thirds of the rectum.

Signup and view all the flashcards

Middle and Inferior Rectal Arteries

Originate from the internal pudendal/iliac arteries and supply the middle and lower portions of the rectum.

Signup and view all the flashcards

Rectum

Continuous with the sigmoid colon at the level of the third sacral vertebra and ends as it passes through the pelvic diaphragm, maintains anorectal flexure

Signup and view all the flashcards

Mesorectum

Distal continuation of the Mesosigmoid, encloses the proximal rectum, contains adipose connective tissue, vessels, and nodes.

Signup and view all the flashcards

Anal Canal

Anal canal begins at the pelvic diaphragm and ends at the anal orifice, It is directed posteroinferiorly because the sling-like pubo-analis pulls the rectum anteriorly to create the anorectal flexure.

Signup and view all the flashcards

Anal Canal Lining

The epithelium below the pectinate line, lined by squamous epithelium, lacks sweat/sebaceous glands, but contains somatic sensory nerve endings conveying pain/temperature/touch.

Signup and view all the flashcards

Internal Anal Sphincter

Tightly spiral which commences at the anorectal junction and ends proximal to the anal orifice, maintaining continence.

Signup and view all the flashcards

External Anal Sphincter

The external anal sphincter forms the bulk of the anal sphincter complex, composed mostly of type I slow twitch muscle fibres for prolonged contraction and is innervated by the inferior anal nerve

Signup and view all the flashcards

Intersphincteric Space

Located between The Internal Anal Sphincter and the External Anal Sphincter from which anal glands may originate.

Signup and view all the flashcards

What is the colon's primary function?

The colon's primary function is the transport and elimination of intestinal contents.

Signup and view all the flashcards

Role of Intrinsic Nerves in Large Intestine

Intrinsic nerves coordinate activity, modulated extrinsically.

Signup and view all the flashcards

Location of Taeniae Coli

The taeniae are located in constant positions beneath the serosa of the colon, except in the transverse colon.

Signup and view all the flashcards

Trefoil Pattern in Caecum

The trefoil pattern is where three taeniae coli converge.

Signup and view all the flashcards

What creates the Haustra?

Visible because of infolding of the colonic wall

Signup and view all the flashcards

Organization of Colic Lymph Nodes

It's divided into epicolic, paracolic, intermediate colic and preterminal colic groups.

Signup and view all the flashcards

Origin of Accessory Appendicular Arteries

They are derived from the superior mesenteric artery or the ileocolic artery.

Signup and view all the flashcards

Appendicular Vein Significance

Connects to liver.

Signup and view all the flashcards

Ileocolic Artery Role

It provides collateral arterial supply through anastomoses.

Signup and view all the flashcards

Branch Origin for Right Colic Artery Anatomy

Originate from the superior mesenteric artery either separately or together.

Signup and view all the flashcards

Anastomoses at Right Colic Flexure

Anastomoses form the marginal artery.

Signup and view all the flashcards

Visceral Afferent Fibers Role

It causes distension and inflammation.

Signup and view all the flashcards

What is Caecal Volvulus?

It is caused by strangulating closed loop obstruction.

Signup and view all the flashcards

Caecum Features

Located lower than the ileocaecal junction, connecting to the ileum

Signup and view all the flashcards

What anatomical features the rectum lacks?

The rectum has no haustra, omental appendices or taeniae coli.

Signup and view all the flashcards

Ureter Relationship to Rectum

Is found lateral to the rectum

Signup and view all the flashcards

A Key Function of Sigmoid Arteries

Provide a collateral arterial supply to the sigmoid colon via mesentery.

Signup and view all the flashcards

Result of Colonic Vascular Occlusion

The artery in the colon becomes dilated.

Signup and view all the flashcards

Describe Lymphoid Aggregates In the Appendix

They are covered by columnar epithelium containing specialized M cells.

Signup and view all the flashcards

Anal Canal Direction

At the anorectal flexure its maintained by pubo-analis.

Signup and view all the flashcards

Caecum

The caecum is a blind pouch marking the beginning of the large intestine, located below the ileocaecal junction.

Signup and view all the flashcards

Colon Wall Thickness

Normal individuals have a thin colon wall.

Signup and view all the flashcards

Colon and Its Relations

An overview of colon and its relations, the large intestine features the caecum, ileum, ascending, transverse, descending an sigmoid colons, rectum, and appendix

Signup and view all the flashcards

Mucous membrane

The middle layer of the gut wall comprising epithelium, lamina propria, and muscularis mucosae

Signup and view all the flashcards

Neuroendocrine cells

Consists of amines and/or peptides, which act as hormones or neurotransmitters. These are derived from APUD cell lineage.

Signup and view all the flashcards

Descending Colon Diameter

The overall luminal diameter is smallest in the descending colon.

Signup and view all the flashcards

Trefoil Pattern

A 'trefoil' pattern on the caecal wall is due to the confluence of the three taeniae coli.

Signup and view all the flashcards

Location of the Caecum

Lies below the level of the ileocaecal junction anterior to the right iliac and psoas fasciae.

Signup and view all the flashcards

What does ileocecal junction achieve?

Performs partial separation

Signup and view all the flashcards

Haustra as Septations

Visible on plain radiographs as incomplete septations arising from the wall.

Signup and view all the flashcards

Appendix Glands

The intestinal glands are sparse and numerous lymphoid follicles are found in the mucosa and submucosa.

Signup and view all the flashcards

APUD Cells in Mucosa

The mucosa also contains scattered neuroendocrine cells derived from the amine precursor uptake decarboxylation (APUD) cell lineage.

Signup and view all the flashcards

Large intention role

Absorption and lubrication

Signup and view all the flashcards

Mesocolon

The mesocolon is the membranous attachment of the transverse colon to the posterior abdominal wall

Signup and view all the flashcards

Enteric Nervous System

Is made up of motor neurones, sensory neurones/interneurones, the ENS controls various gut funtions

Signup and view all the flashcards

Ascending Colon Wall

The wall of the colon is thinnest in the region of the caecum and ascending colon

Signup and view all the flashcards

The weakest link

The most likely susceptible part of the chain of anastomosing vessels is at the distal transverse colon near the left colic flexure

Signup and view all the flashcards

The ileocolic artery action

It gives off a recurrent appendicular branch and the main cecal artery provides a blood supply

Signup and view all the flashcards

Arterial Supply

The arterial supply is augmented to an inner arterial arc (of Riolan) located in the transverse colon and descending to form a anastomosis that augment

Signup and view all the flashcards

Ileocaecal Junction Roles

It performs several roles: it provides partial mechanical and functional separation of the luminal environments of the small and large intestine.

Signup and view all the flashcards

Study Notes

Okay, here are the study notes updated with information from the provided text.

  • The large intestine plays a role in absorption
  • Plays a role in secretion
  • Approximate length of the large intestine in adults, in vivo, is 1–1.5 m, but considerable individual variation is present
  • The average internal diameter is 4.8 cm
  • In utero, large intestine is temporarily suspended with midline dorsal mesentery
  • The descending colon has thinning walls in the caceum
  • The proximal colon is at risk of perforation
  • Three taeniae coli are in constant positions beneath the serosa, apart form the transverse colon
  • Taenae coli are the free taenia, the omental taenia, and the mesocolic taenia
  • The external haustra of the colon represent the mucosa and submucosa infolding

Innervation

  • The large intestine has an intrinsic enteric nerve supply
  • It's activity is modulated by extrinsic innervation

General Information

  • Antimesenteric aspect of the colon, directly opposite the mesentary has the free taeniae
  • Omental Taenia is posterolateral
  • The mesocolic taenia is halfway between the free taenia andmesentery
  • In the ascending the free taenia runs opposite the mesentery
  • In the ascending colon and descending colon, omental taeniae are often hidden.
  • The taeniae rotate in the transverse colon because of it's dependent position
  • Anterior taeniae become inferior, posteromedial becomes posterior, and posterolateral becomes superior
  • They tend to be absent from the caecum, appendix and rectum and colonic wall
  • Omental appendices are pouches of peritoneum that project from the external surface of the colon filled with fat
  • They are supplied by blood vessels that perforate the wall of the colon
  • The rectum has a complete longitudinal muscle layer, and no external haustra.
  • Intestinal glands contain very high amounts of goblet, mucin-secreting cells
  • The appendix has sparse glands and large amounts of lymphoid follicles in the mucosa and submucosa

Colon Appearance

  • Aids assessment of the level reached during flexible endoscopic examinations.
  • In the caecum, the three taeniae coli converge to a trefoil pattern on the caecal wall.
  • The distal caecum typically has no haustra, but may have a spiral mucosal pattern at the appendiceal orifice.
  • Ileal Orifice is a thickened fold and cannulated to examine the terminal ileum.
  • Distal caecum and ascending colon haustra extend across one-third of the lumen.
  • Often confer a triangular cross-section of the transverse colon lumber
  • Descending and sigmoid Colon - haustra are thicker and shorter, creating a more circular cross-section
  • Luminal diameter diminishes in the descending colon.
  • Internal mucosal vessels more visible than in earlier locations.
  • Distinct veins are most marked above the anorectal junction.
  • Omental appendices are numerous on the sigmoid colon

Radiological Appearances

  • Colon may appear filled with particulate feces and flatus on images
  • Caecum and ascending colon contain faecal residue
  • Transverse Colon lies in variable positions
  • Multi-slice CT can create virtual colonoscopic mucosal images

Ileocaecal Junction

  • The terminal ileum joins the posteromedial aspect of the large intestine at the junction of the caecum and colon
  • It projects into the lumen as the ileal papilla
  • The papilla consists of two lips, varying in shape depending on contractions
  • The ileocolic lip is horizontal and at the ileum/colon junction
  • The ileocaecal lip is longer, concave, at the ileum/caecum junction
  • At bases, the lips fuse and continue as the frenulum of the ileal orifice
  • The ileal papilla is formed by mucosa, submucosa, and external muscle layers from the ileum, continuing through the large intestine wall

Appendix Positions

  • Distal end may occupy several positions
  • Most commonly retrocaecal or retrocolic (behind the caecum/proximal ascending colon)
  • Anterior to iliacus and psoas major
  • Other positions: pelvic , subcaecal, pre- or post-ileal
  • A long meso-appendix allows greater mobility
  • McBurney's point marks the base of the location on a 2/3s line from the anterior superior iliac spine, though there is affect from distension and other factors

Appendix Artery

  • Has a continuous outer layer of longitudinal muscle formed through the coalescence of the three taeniae coli
  • Its lumen is irregularly narrowed by submucosal lymphoid tissue
  • A triangular mesentery runs between the terminal ileum and appendix, ending short the appendix's distal end
  • The meso-appendix contains varying fat
  • A peritoneal fold runs between the terminal ileum and the meso-appendix's anterior layer called Treves' fold
  • Another fold containing the anterior caecal vessels runs from the ileal mesentery to the caecum anterior wall
  • There is a mucosal fold sometimes partially covering the luminal orifice, creating valve
  • Agenesis and duplication are extremely rare

Mid Gut Arterial Supply

  • The superior mesenteric artery runs posterior to the splenic vein
  • It is anterior to the left renal vein and the horizontal part of the duodenum
  • Aorta is at the level of the lower border of the first lumbar vertebra

Ileocolic Artery

  • Arises from the superior mesenteric artery near root of small intestine mesentery
  • Descends to the right to the caecum
  • Crosses anterior to the right ureter, gonadal vessels, and psoas major
  • It branches into superior and inferior branches
  • Anastomoses with right colic artery

Appendicular Artery

  • Usually arises directly from the ileocolic artery
  • It descends posterior to the terminal ileum
  • A recurrent branch anastomoses at appendix proximal with a branch of the posterior caecal artery
  • The artery terminal part can become thrombosed in appendicitis

Accessory Appendicular Artery

  • Less common
  • May receive blood supply from posterior caecal artery or ileal artery
  • More than ore artery may supply the appendix

Right Colic Artery

  • Variable in size - can be small
  • Can arise a common trunk with middle colic artery
  • Can originate directly from the SMA of from the ileocolic artery and is called accessory right colic artery(
  • Passes to right, across the right psoas major and quadratus lumborum

Colon Alignment

  • The ascending colon passes superiorly in the right lateral region to the right hypochondriac region
  • There it bends to the left to form the right colic flexure and become the transverse colon
  • The transverse colon loops across the abdomen with an anteroinferior convexity
  • The tranverse colon reaches the left hypochondriac region, where it curves inferiorly to form the left colic flexure (Fig. 65.2)
  • From there, descends in the left lateral region as the descending colon before continuing as the sigmoid colon in the left iliac region.
  • The sigmoid colon descends into the lesser pelvis
  • The sigmoid colon then becomes the rectum anterior to the third sacral vertebra.
  • The rectum transitions to the anal canal at the level of the pelvic diaphragm

Colon Sections

  • The caecum has a lack of sparse hauster
  • The ascending colon is usually aherent to the retroperitoneum
  • The right and left flexures may have a short mesentery
  • The transverse colon is suspended by a mesocolon allowing movement
  • The descending colon is ususally addherent to the retroperitoneum, down to the level of the iliac crest
  • The sigmoid colon has a mesentery of variable length that disappears as it approaches the pelvis
  • The distal rectum is below the peritoneum

Wall Layers

  • The microstructure of the large intestine corresponds to the general pattern of the gut wall
  • The mucous membrane consists of epithelium, lamina propria, and muscularis mucosae
  • There is an inner circular and outer longitudinal layers of smooth muscle
  • Surrounded by serosa
  • Mucosa contains scattered neuroendocrine cells derived from the amine precursor uptake and decarboxylation (APUD) cell lineage

Taeniae Placement

  • On the antimesenteric aspect of the colon, directly opposite the mesentery has the free taeniae
  • Omental Taeniae, or taeniae libera are posterolateral
  • The mesocolic taenia is postermedial.
  • In the ascending and descending colon, the omental taeniae are often hidden by the peritoneal reflection on to the colonic wall
  • Taeniae rotate as a consequence of the dependent position of the transverse colon.
  • Anterior taeniae become inferior, posteromedial becomes posterior, and posterolateral becomes superior
  • They tend to be absent from the caecum, appendix and rectum and colonic wall
  • Omental appendices are numerous on teh sigmoid colon

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

Related Documents

More Like This

Large Intestine Anatomy Study Notes
19 questions
Colon Anatomy and Physiology
51 questions
Use Quizgecko on...
Browser
Browser