Langerhans Cells and Immunity
18 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What regulates melanocyte differentiation?

  • Melanosomes
  • Keratinocytes
  • MITF (correct)
  • Tyrosinase enzymes
  • Which enzyme catalyzes the conversion of Tyrosine to DOPA within the melanosome?

  • Tyrosinase (Tyr) (correct)
  • Phenylalanine hydroxylase
  • MITF
  • Keratinocytes
  • What happens in individuals with a mutation in the gene for tyrosinase?

  • Less melanin production (correct)
  • Increased melanin production
  • Enhanced keratinocyte maturation
  • Vitiligo development
  • Which skin condition is characterized by autoimmune loss of melanocytes?

    <p>Vitiligo</p> Signup and view all the answers

    Where does the synthesis of Vitamin D3 occur?

    <p>Keratinocytes</p> Signup and view all the answers

    What is responsible for the formation of the epidermal permeability barrier?

    <p>Cell junctions</p> Signup and view all the answers

    What is the primary role of Langerhans cells in the immune response?

    <p>Recognizing and presenting antigens to the immune system</p> Signup and view all the answers

    Which type of cells are Langerhans cells derived from?

    <p>Bone marrow-derived dendritic cells</p> Signup and view all the answers

    How do Langerhans cells interact with keratinocytes?

    <p>Via E-cadherin association</p> Signup and view all the answers

    What is the main function of keratinocytes in the epidermis?

    <p>Form the epidermal permeability barrier</p> Signup and view all the answers

    Which process leads to the production of Vitamin D3 in the skin?

    <p>Exposure to UV radiation</p> Signup and view all the answers

    What is the primary source of melanin production in the skin?

    <p>Keratinocytes</p> Signup and view all the answers

    What is the main function of the epidermal permeability barrier?

    <p>Prevent dehydration</p> Signup and view all the answers

    Which of the following is NOT a function of the skin?

    <p>Vitamin C synthesis</p> Signup and view all the answers

    What is the main component produced by melanocytes in the skin?

    <p>Melanin</p> Signup and view all the answers

    Which layer of the skin is responsible for the synthesis of Vitamin D3?

    <p>Epidermis</p> Signup and view all the answers

    What is the primary role of Langerhans cells in the skin?

    <p>Immunity</p> Signup and view all the answers

    Which type of junctions are present between cells in the skin?

    <p>Desmosomes</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Browser