Lactose as a Pharmaceutical Excipient

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NonViolentKyanite
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8 Questions

What is the main disadvantage of lactose mentioned in the text?

Chemical reactions towards amines

How is spray-dried lactose produced?

Using a powder aerosol process

How does crystalline lactose differ from modified lactose like spray dry lactose?

Crystalline lactose is stronger and harder but less compressible

How is milled lactose different from sieved lactose?

Differ in both particle size and morphology

What property of lactose makes it unsuitable for direct compression into tablets?

It is not directly compressible

Why is agglomerated lactose more prone to Maillard reactions compared to other types?

It has higher chemical reactivity

What is the main issue associated with spray-dried lactose?

Excessive moisture content

What is the key difference between crystalline α-lactose monohydrate and crystalline β-lactose monohydrate?

Maillard reaction rate

Test your knowledge of the advantages and disadvantages of lactose as a pharmaceutical excipient. Learn about its solubility, taste, inertness, and potential drawbacks such as lactose intolerance and chemical reactivity.

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