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Questions and Answers
What is the main disadvantage of lactose mentioned in the text?
What is the main disadvantage of lactose mentioned in the text?
- Reducing properties affecting stability of tablets
- Chemical reactions towards amines (correct)
- Lactose intolerance in some patients
- Hygroscopic nature leading to moisture uptake
How is spray-dried lactose produced?
How is spray-dried lactose produced?
- Using a powder aerosol process (correct)
- Forming coarse particles through a slow drying process
- Mixing liquid lactose with a hot drying chamber
- Spraying liquid lactose solution into a cold drying chamber
How does crystalline lactose differ from modified lactose like spray dry lactose?
How does crystalline lactose differ from modified lactose like spray dry lactose?
- Modified lactose is obtained through sieving
- Modified lactose has ordered crystals
- Crystalline lactose is in amorphous form and softer
- Crystalline lactose is stronger and harder but less compressible (correct)
How is milled lactose different from sieved lactose?
How is milled lactose different from sieved lactose?
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What property of lactose makes it unsuitable for direct compression into tablets?
What property of lactose makes it unsuitable for direct compression into tablets?
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Why is agglomerated lactose more prone to Maillard reactions compared to other types?
Why is agglomerated lactose more prone to Maillard reactions compared to other types?
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What is the main issue associated with spray-dried lactose?
What is the main issue associated with spray-dried lactose?
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What is the key difference between crystalline α-lactose monohydrate and crystalline β-lactose monohydrate?
What is the key difference between crystalline α-lactose monohydrate and crystalline β-lactose monohydrate?
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