Lactoferrin Binding on Microorganisms

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Questions and Answers

What is the hypothesized anchoring site for Lf on the surface of Gram-negative bacteria?

  • Porins (correct)
  • Glycans
  • Iron acquisition systems
  • Lipid-A moiety

How does Lf influence the release of LPS from bacteria?

  • By binding to lipid-A moiety
  • By chelating iron (correct)
  • By binding to bacterial adhesins
  • By competing with iron acquisition systems

What does Bovine Lf inhibit the integrin-mediated internalization of into host cells through its binding to?

  • Glycans
  • Porins
  • Lipid-A moiety
  • Viral polypeptides II and III (correct)

What does Lf limit in order to prevent septic shock associated with bacterial infections?

<p>Production of pro-inflammatory cytokines (C)</p> Signup and view all the answers

What does the chelation of iron by apoLf during inflammation help prevent?

<p>Formation of hydroxyl radicals (C)</p> Signup and view all the answers

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