Questions and Answers
What is the purpose of a 'cut-off' in rapid tests?
To identify the point or level at which tests will be positive.
What are the two important characteristics of a lab test procedure?
Sensitivity and specificity.
What is the term for the process of repeating a test with a lower concentration of the analyte to get a readable result?
Dilutions.
What is the term that refers to the range of values over which a test gives a directly proportional response?
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What is the difference between qualitative and quantitative testing?
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What is the term for the weaknesses or flaws of a lab test procedure?
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Study Notes
Laboratory Maths Applications
- The laboratory is filled with various areas that require data or mathematical applications.
Statistical Involvement in Testing
- Persons involved in qualitative or quantitative testing must appreciate the degree of statistical involvement.
Rapid Tests
- Rapid tests come with a "cut-off" point that identifies when tests will be positive.
Limitations of Lab Test Procedures
- Lab test procedures have limitations, including:
- Sensitivity (ability to detect low levels or concentrations of the analyte being investigated)
- Specificity (ability to detect what they are supposed to detect)
Linearity and Dilutions
- High test results may exceed the analyzer's or reagent's capacity, requiring dilutions to repeat and obtain final results.
- Final results are multiplied by the dilution factor after repeating the test.
Important Terms
- Qualitative: related to the quality or kind of something
- Quantitative: related to the amount or degree of something
- Cut-off: the point or level at which tests will be positive
- Dilutions: reducing the concentration of a solution or substance
- Sensitivity: the ability of a test to detect low levels or concentrations of the analyte
- Specificity: the ability of a test to detect what it is supposed to detect
- Limitations: the restrictions or weaknesses of a test procedure
- Linearity: the degree to which the relationship between the concentration of the analyte and the test result is directly proportional
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