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Questions and Answers
Which laboratory marker is specific to chronic heavy alcohol consumption, but can be affected by other liver diseases?
Which laboratory marker is specific to chronic heavy alcohol consumption, but can be affected by other liver diseases?
- Aspartate Transaminase (AST)
- Carbohydrate-Deficient Transferrin (CDT) (correct)
- Alanine Transaminase (ALT)
- Gamma-Glutamyl Transferase (GGT)
What is the duration of detectability of Ethyl Glucuronide (EtG) in urine after consumption?
What is the duration of detectability of Ethyl Glucuronide (EtG) in urine after consumption?
- Up to 80 hours (correct)
- Up to 24 hours
- Up to 48 hours
- Up to 120 hours
Which of the following laboratory markers is a sensitive indicator of heavy alcohol consumption, but can also be elevated in other liver diseases?
Which of the following laboratory markers is a sensitive indicator of heavy alcohol consumption, but can also be elevated in other liver diseases?
- Aspartate Transaminase (AST)
- Alanine Transaminase (ALT)
- Gamma-Glutamyl Transferase (GGT) (correct)
- Mean Corpuscular Volume (MCV)
What is the duration of detectability of Phosphatidylethanol (PEth) in whole blood after consumption?
What is the duration of detectability of Phosphatidylethanol (PEth) in whole blood after consumption?
Which of the following laboratory markers is a marker of liver damage, but not specific to alcoholism?
Which of the following laboratory markers is a marker of liver damage, but not specific to alcoholism?
What is the duration of detectability of 5-Hydroxytryptophol (5-HTOL) in urine after consumption?
What is the duration of detectability of 5-Hydroxytryptophol (5-HTOL) in urine after consumption?
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Study Notes
Detection of an Alcoholic Group: Laboratory Markers
Blood Tests
- Mean Corpuscular Volume (MCV): Elevated MCV is a common finding in chronic alcoholics, but not specific to alcoholism.
- Gamma-Glutamyl Transferase (GGT): Elevated GGT is a sensitive indicator of heavy alcohol consumption, but can also be elevated in other liver diseases.
- Aspartate Transaminase (AST): Elevated AST is a marker of liver damage, but not specific to alcoholism.
- Alanine Transaminase (ALT): Elevated ALT is a marker of liver damage, but not specific to alcoholism.
- Carbohydrate-Deficient Transferrin (CDT): Elevated CDT is a specific marker of chronic heavy alcohol consumption, but can be affected by other liver diseases.
Urine Tests
- Ethanol: Detectable in urine for up to 24 hours after consumption.
- Ethyl Glucuronide (EtG): Detectable in urine for up to 80 hours after consumption, and is a specific marker of recent alcohol consumption.
- Ethyl Sulfate (EtS): Detectable in urine for up to 24 hours after consumption, and is a specific marker of recent alcohol consumption.
Other Markers
- Phosphatidylethanol (PEth): A specific marker of chronic heavy alcohol consumption, detectable in whole blood for up to 28 days after consumption.
- 5-Hydroxytryptophol (5-HTOL): A marker of recent alcohol consumption, detectable in urine for up to 24 hours after consumption.
Note: These laboratory markers can be used in combination to increase the accuracy of detection, but should be interpreted in conjunction with clinical evaluation and patient history.
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