Laboratory Markers for Detecting Alcoholic Groups

Which laboratory marker is specific to chronic heavy alcohol consumption, but can be affected by other liver diseases?

What is the duration of detectability of Ethyl Glucuronide (EtG) in urine after consumption?

Which of the following laboratory markers is a sensitive indicator of heavy alcohol consumption, but can also be elevated in other liver diseases?

What is the duration of detectability of Phosphatidylethanol (PEth) in whole blood after consumption?

Which of the following laboratory markers is a marker of liver damage, but not specific to alcoholism?

What is the duration of detectability of 5-Hydroxytryptophol (5-HTOL) in urine after consumption?

Detection of an Alcoholic Group: Laboratory Markers

Blood Tests

Mean Corpuscular Volume (MCV): Elevated MCV is a common finding in chronic alcoholics, but not specific to alcoholism.
Gamma-Glutamyl Transferase (GGT): Elevated GGT is a sensitive indicator of heavy alcohol consumption, but can also be elevated in other liver diseases.
Aspartate Transaminase (AST): Elevated AST is a marker of liver damage, but not specific to alcoholism.
Alanine Transaminase (ALT): Elevated ALT is a marker of liver damage, but not specific to alcoholism.
Carbohydrate-Deficient Transferrin (CDT): Elevated CDT is a specific marker of chronic heavy alcohol consumption, but can be affected by other liver diseases.

Urine Tests

Ethanol: Detectable in urine for up to 24 hours after consumption.
Ethyl Glucuronide (EtG): Detectable in urine for up to 80 hours after consumption, and is a specific marker of recent alcohol consumption.
Ethyl Sulfate (EtS): Detectable in urine for up to 24 hours after consumption, and is a specific marker of recent alcohol consumption.

Other Markers

Phosphatidylethanol (PEth): A specific marker of chronic heavy alcohol consumption, detectable in whole blood for up to 28 days after consumption.
5-Hydroxytryptophol (5-HTOL): A marker of recent alcohol consumption, detectable in urine for up to 24 hours after consumption.

Note: These laboratory markers can be used in combination to increase the accuracy of detection, but should be interpreted in conjunction with clinical evaluation and patient history.

This quiz covers the laboratory tests used to detect alcohol consumption, including blood and urine tests, and their specificity and sensitivity in diagnosing alcoholism. It also discusses the importance of combining these tests with clinical evaluation and patient history for accurate detection. The quiz is ideal for medical students, healthcare professionals, and researchers working in the field of addiction and substance abuse.